Normal Saline for Hypoxia

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
University of Missouri-Columbia, Columbia, MOHypoxia+1 MoreNormal Saline - Drug
Eligibility
18 - 45
All Sexes
What conditions do you have?
Select

Study Summary

This trial will investigate how different sexes respond to hypoxia, or low oxygen levels.

Eligible Conditions
  • Hypoxia
  • Vasodilation

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

1 Primary · 0 Secondary · Reporting Duration: Change from baseline to 10 minutes

Change from baseline to 10 minutes
Forearm Blood Flow

Trial Safety

Safety Progress

1 of 3

Trial Design

1 Treatment Group

Hypoxia Exposure
1 of 1

Experimental Treatment

35 Total Participants · 1 Treatment Group

Primary Treatment: Normal Saline · Has Placebo Group · Phase < 1

Hypoxia ExposureExperimental Group · 3 Interventions: Placebo, Propranolol Hydrochloride, Normal Saline · Intervention Types: Drug, Drug, Drug
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Placebo
1995
Completed Phase 3
~2640
Propranolol Hydrochloride
2021
Completed Phase 3
~290
Normal Saline
2019
Completed Phase 4
~1790

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: change from baseline to 10 minutes

Who is running the clinical trial?

University of Missouri-ColumbiaLead Sponsor
332 Previous Clinical Trials
600,747 Total Patients Enrolled
3 Trials studying Hypoxia
154 Patients Enrolled for Hypoxia
American Heart AssociationOTHER
286 Previous Clinical Trials
5,824,203 Total Patients Enrolled
2 Trials studying Hypoxia
60 Patients Enrolled for Hypoxia
Jacqueline K Limberg, Ph.D.Principal InvestigatorUniversity of Missouri-Columbia
3 Previous Clinical Trials
111 Total Patients Enrolled
1 Trials studying Hypoxia
54 Patients Enrolled for Hypoxia

Eligibility Criteria

Age 18 - 45 · All Participants · 5 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
Men and women who are generally in good health.
You have a body mass index (BMI) between 18 and 30, which means you are not underweight or overweight.
You do not use nicotine.

Frequently Asked Questions

Are individuals aged 65 or older eligible for enrollment in this trial?

"To comply with the stipulated requirements of this study, eligible participants must be aged 18 to 45." - Anonymous Online Contributor

Unverified Answer

Are any participants still needed for this research experiment?

"Affirmative. Clinicaltrials.gov exhibits that this experiment, initially posted on February 1st 2023 and most recently updated 11/11/2022, is actively seeking participants. 35 individuals are being sought after at a single medical site." - Anonymous Online Contributor

Unverified Answer

Who meets the criteria to be eligible for enrollment in this medical experiment?

"Qualified participants must express vasodilation and be between 18-45 years old. This research study is expected to recruit up to 35 patients." - Anonymous Online Contributor

Unverified Answer

To what extent is the scope of this clinical trial limited by a participant quota?

"Affirmative. Clinicaltrials.gov indicates that this research is in the process of enrolling participants, with an initial posting date of February 1st 2023 and a latest update on November 11th 2022. The investigation is attempting to recruit 35 individuals from one medical centre." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.