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Fine-Needle Aspiration for Esophagus

Phase < 1
Waitlist Available
Led By Ji-Bin Liu, MD
Research Sponsored by Sidney Kimmel Cancer Center at Thomas Jefferson University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 2 years
Awards & highlights

Study Summary

This trial is testing how well an ultrasound with a contrast agent can find sentinel lymph nodes in people with esophageal cancer.

Eligible Conditions
  • Esophagus

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 2 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 2 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Accuracy rate of traditional endoscopic ultrasonography (EUS) with suspicious node biopsy and lymphosonography for sentinel node identification
Secondary outcome measures
Number of nodes identified

Trial Design

1Treatment groups
Experimental Treatment
Group I: Diagnostic (EUS, FNA, perflubutane microbubble)Experimental Treatment4 Interventions
Participants undergo standard of care unenhanced endoscopic ultrasound (EUS) and fine needle aspiration (FNA) of identified lymph nodes. Participants then receive perflubutane microbubble peri- or intratumorally and undergo contrast-enhanced EUS followed by FNA of identified lymph nodes.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Fine-Needle Aspiration
2018
Completed Early Phase 1
~40
Sonazoid (Perflubutane)
2018
Completed Early Phase 1
~40
Endoscopic Ultrasound-Guided Fine-Needle Aspiration (EUS-FNA)
2018
Completed Early Phase 1
~40
Contrast-Enhanced Ultrasound
2018
Completed Early Phase 1
~50

Find a Location

Who is running the clinical trial?

Sidney Kimmel Cancer Center at Thomas Jefferson UniversityLead Sponsor
162 Previous Clinical Trials
10,876 Total Patients Enrolled
National Cancer Institute (NCI)NIH
13,658 Previous Clinical Trials
40,924,454 Total Patients Enrolled
Ji-Bin Liu, MDPrincipal InvestigatorSidney Kimmel Cancer Center at Thomas Jefferson University

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Contrast-Enhanced Ultrasound Identification of Sentinel Nodes in Esophageal Cancer
2018. "Contrast-Enhanced Ultrasound Identification of Sentinel Nodes in Esophageal Cancer". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03578224.
~5 spots leftby Apr 2025
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