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MR-PET vs PET-CT Scanning for Gynecological Cancers

Q: Are there any current openings for participation in this clinical experiment?

<p>According to the clinicaltrials.gov listing, this research project is not presently seeking volunteers. The trial was originally posted in March 2013 and last edited on January 28th of that same year. Nevertheless, 837 other medical trials are currently accepting applicants at this time.</p>

Phase < 1

Waitlist Available

Led By Michael Birrer, MD, PhD

Research Sponsored by Massachusetts General Hospital

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Able to undergo extra-peritoneal or laparoscopic lymph node sampling

Histologically confirmed cervical, endometrial or ovarian cancer

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 2 years

Awards & highlights

Study Summary

This trial will enroll up to 50 participants with various types of cancer. The investigators hope that the use of this new scanner will help doctors better detect, diagnose, and stage various types of cancer.

Who is the study for?

This trial is for individuals with confirmed cervical, endometrial, or ovarian cancer who are suitable for surgery and can undergo lymph node sampling. It's not for those with kidney issues, electrical or ferromagnetic implants, prior pelvic radiation therapy, pregnancy/breastfeeding, certain medical conditions including claustrophobia or high cardiac arrest risk.Check my eligibility

What is being tested?

The study compares two imaging methods: MR-PET (a new combined MRI and PET scan) versus the standard PET-CT scan to see which provides better tumor images in gynecological cancers. The MR-PET scanner is FDA-approved but uses some experimental software.See study design

What are the potential side effects?

Potential side effects may include discomfort from lying still during scans and reactions to contrast dyes used in imaging. There's also a small exposure to radiation similar to x-rays during PET scans.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I can have a minor surgery to check my lymph nodes.

Select...

My cancer is confirmed in the cervix, endometrium, or ovaries.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 2 years

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~2 years

This trial's timeline: 3 weeks for screening, Varies for treatment, and 2 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Evaluate Diagnostic Sensitivity and Specificity of Preoperative MR/PET vs. FDG-PET/CT

Evaluate Diagnostic Sensitivity and Specificity of Preoperative MR/PET vs. PET/CT

Secondary outcome measures

Determine Percentage of Participants in Whom MR/PET (relative to PET/CT) Detects Biopsy Proven Disease

Evaluate Additive Diagnostic Value of MRI Fusion

Trial Design

1Treatment groups

Experimental Treatment

Group I: Experimental ArmExperimental Treatment2 Interventions

PET/CT Scan MR-PET Scan

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

MR-PET

2015

N/A

~10

PET-CT

2014

N/A

~570

0 / 2Eligibility criteria met

Find a Location

Who is running the clinical trial?

Massachusetts General HospitalLead Sponsor

2,928 Previous Clinical Trials

13,198,255 Total Patients Enrolled

Michael Birrer, MD, PhDPrincipal InvestigatorMassachusetts General Hospital

1 Previous Clinical Trials

10,000 Total Patients Enrolled

Media Library

MR-PET Clinical Trial Eligibility Overview. Trial Name: NCT01779128 — Phase < 1

Cervical Cancer Research Study Groups: Experimental Arm

Cervical Cancer Clinical Trial 2023: MR-PET Highlights & Side Effects. Trial Name: NCT01779128 — Phase < 1

MR-PET 2023 Treatment Timeline for Medical Study. Trial Name: NCT01779128 — Phase < 1

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there any current openings for participation in this clinical experiment?

"According to the clinicaltrials.gov listing, this research project is not presently seeking volunteers. The trial was originally posted in March 2013 and last edited on January 28th of that same year. Nevertheless, 837 other medical trials are currently accepting applicants at this time."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

PET-CT vs. Integrated MR-PET Scanning of GYN Cancers

Michael J. Birrer,M.D.,Ph.D. 2013. "PET-CT vs. Integrated MR-PET Scanning of GYN Cancers". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT01779128.

All > Cervical Cancer