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Radiation Therapy

CT angiography for Arteriovenous Malformations

Phase < 1
Waitlist Available
Led By Robert Timmerman, MD
Research Sponsored by University of Texas Southwestern Medical Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Documented AVM with draining vein(s).
Adequate renal function (within 30 days) to undergo contrast CT and interventional cerebral arteriography on the same day, as determined by treating physicians.
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 1 day
Awards & highlights

Study Summary

This trial will compare the accuracy of a treatment plan based on CT angiography to standard cerebral arteriography fused to MRI in identifying the target nidus.

Eligible Conditions
  • Arteriovenous Malformations

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~1 day
This trial's timeline: 3 weeks for screening, Varies for treatment, and 1 day for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
To evaluate whether target(s) based on CT angiogram can accurately and precisely identify the target nidus as well as an interventional cerebral arteriography.
Secondary outcome measures
To analyze and compare dosimetric parameters: planning target volume
To analyze and compare dosimetric parameters: volume of the brain that receives at least 12 Gray of radiaton (V12)
To evaluate the total time it takes to perform the additional CT angiograms and compare it to the duration of the interventional procedure.

Trial Design

1Treatment groups
Experimental Treatment
Group I: Patient with AVM requiring radiotherapyExperimental Treatment1 Intervention
Patients on this protocol will still get treated based on target generated by interventional cerebral arteriography but also receive CT angiography.

Find a Location

Who is running the clinical trial?

University of Texas Southwestern Medical CenterLead Sponsor
1,047 Previous Clinical Trials
1,053,785 Total Patients Enrolled
Robert Timmerman, MDPrincipal InvestigatorUniversity of Texas Southwestern Medical Center
4 Previous Clinical Trials
459 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Treating Arteriovenous Malformation With Stereotactic Radiosurgery Using CT Angiography for Treatment Planning
Robert Timmerman 2019. "Treating Arteriovenous Malformation With Stereotactic Radiosurgery Using CT Angiography for Treatment Planning". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03559556.
All > Sbrt
~2 spots leftby Apr 2025
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