Study Summary
This trial will compare the effects of a daily dose of pregnenolone (PREG) to a placebo (PLA) in individuals with cocaine use disorder (CUD).
Treatment Effectiveness
Effectiveness Progress
Study Objectives
10 Primary · 2 Secondary · Reporting Duration: at week 8
Trial Safety
Safety Progress
Trial Design
2 Treatment Groups
patients receiving PREG
1 of 2
patients receiving placebo
1 of 2
Experimental Treatment
Non-Treatment Group
60 Total Participants · 2 Treatment Groups
Primary Treatment: PREG 300/500 mg · Has Placebo Group · Phase < 1
Trial Logistics
Trial Timeline
Who is running the clinical trial?
Eligibility Criteria
Age 18 - 60 · All Participants · 4 Total Inclusion Criteria
Mark “Yes” if the following statements are true for you:Who else is applying?
What state do they live in?
| Tennessee | 50.0% |
| New York | 50.0% |
How old are they?
| 18 - 65 | 100.0% |
What site did they apply to?
| Yale Stress Center | 100.0% |
What portion of applicants met pre-screening criteria?
| Did not meet criteria | 50.0% |
| Met criteria | 50.0% |
How responsive is this trial?
Typically responds via
| 100.0% | |
Frequently Asked Questions
Is this research project accepting participants who are over 35 years of age?
"This study is open to those who meet the age requisites of being 18 years or older and younger than 60." - Anonymous Online Contributor
Who is eligible to engage in this examination?
"This research project is accepting aproximately 60 participants that have cocaine addiction, and are aged between 18 to 60 years old." - Anonymous Online Contributor
What is the current enrollment size of this experiment?
"Affirmative. Evidenced by clinicaltrials.gov, this investigation is currently recruiting participants; the original post was published on March 12th 2019 and edited most recently on March 9th 2022. This trial requires 60 patients to be registered at one medical site." - Anonymous Online Contributor
Are volunteers sought for this research project?
"Per the information on clinicaltrials.gov, this study is actively seeking out participants having initially been posted on March 12th 2019 and being most recently updated on March 9th 2022." - Anonymous Online Contributor