← Back to Search

Other

Salt Intake for Cardiovascular Disease

Q: Does my health profile qualify me for participation in this medical experiment?

Participants in this medical trial must be between 21 and 65 years of age, possess <a href="https://www.withpower.com/clinical-trials/cardiovascular">cardiovascular</a> disease (CVD), and display the capacity to actively participate in study procedures. In total, 150 individuals are being recruited for enrollment.

Q: How many individuals have the capacity to join this research project?

Affirmative. Per the information on clinicaltrials.gov, this medical study is currently recruiting participants. The trial was initially posted on January 22nd 2021 and updated most recently on September 16th 2022. With 150 patients needed at 1 site, enrollment has begun in earnest.

Q: Are participants currently being enrolled in this research endeavor?

Affirmative. According to the details available on clinicaltrials.gov, this study is actively enrolling participants and has been doing so since its initial posting on January 22nd 2021. It was last updated September 16th 2022 and requires 150 people from a single medical centre for completion.

Q: Are individuals aged 40 or above able to partake in this clinical experiment?

Patients aged 21 to 65 are qualified for this clinical trial, while those below 18 and above 65 should refer to the respective 27 or 378 other studies.

Phase < 1

Waitlist Available

Led By Gary H Gibbons, M.D.

Research Sponsored by National Human Genome Research Institute (NHGRI)

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up two-three years

Awards & highlights

Study Summary

This trial is looking at how African Americans react to salt in their diet to see if there is a difference in how their bodies process it.

Who is the study for?

This trial is for U.S.-born African American adults aged 21-65, who previously participated in GENE-FORECAST and have normal blood pressure. It's not for those with heart disease, stroke, diabetes, liver/kidney diseases, or on certain medications. Pregnant/breastfeeding individuals or those unable to consent are also excluded.Check my eligibility

What is being tested?

The study tests the body's response to increased salt intake through placebo or sodium chloride capsules taken daily over two separate two-week periods. Participants will discuss their diet and physical activity, complete taste tasks, and provide various biological samples.See study design

What are the potential side effects?

While the trial primarily involves dietary intervention (salt capsules), potential side effects may include changes in blood pressure or related cardiovascular responses due to increased sodium intake.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ two-three years

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~two-three years

This trial's timeline: 3 weeks for screening, Varies for treatment, and two-three years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

What effect does increase dietary sodium intake have on vascular function and microbiome?

Trial Design

3Treatment groups

Active Control

Placebo Group

Group I: WASHOUT OUT PERIODActive Control1 Intervention

Participant will have a wash-out period for three-weeks.

Group II: PERIOD 1Placebo Group2 Interventions

Participant will be instructed to take 3 pills per day for a total of 3 grams. Participant will take Sodium Chloride or placebo for a two week period.

Group III: PERIOD 2Placebo Group2 Interventions

Participant will be instructed to take 3 pills per day for a total of 3 grams. Participant will take Sodium Chloride or placebo for a two week period.

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

National Human Genome Research Institute (NHGRI)Lead Sponsor

263 Previous Clinical Trials

284,104 Total Patients Enrolled

Gary H Gibbons, M.D.Principal InvestigatorNational Human Genome Research Institute (NHGRI)

3 Previous Clinical Trials

3,000 Total Patients Enrolled

Amadou Gaye, M.D.Principal InvestigatorNational Human Genome Research Institute (NHGRI)

3 Previous Clinical Trials

3,000 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does my health profile qualify me for participation in this medical experiment?

"Participants in this medical trial must be between 21 and 65 years of age, possess cardiovascular disease (CVD), and display the capacity to actively participate in study procedures. In total, 150 individuals are being recruited for enrollment."

Answered by AI

How many individuals have the capacity to join this research project?

"Affirmative. Per the information on clinicaltrials.gov, this medical study is currently recruiting participants. The trial was initially posted on January 22nd 2021 and updated most recently on September 16th 2022. With 150 patients needed at 1 site, enrollment has begun in earnest."

Answered by AI

Are participants currently being enrolled in this research endeavor?

"Affirmative. According to the details available on clinicaltrials.gov, this study is actively enrolling participants and has been doing so since its initial posting on January 22nd 2021. It was last updated September 16th 2022 and requires 150 people from a single medical centre for completion."

Answered by AI

Are individuals aged 40 or above able to partake in this clinical experiment?

"Patients aged 21 to 65 are qualified for this clinical trial, while those below 18 and above 65 should refer to the respective 27 or 378 other studies."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Genomics, Environmental Factors and Social Determinants of Cardiovascular Disease in African Americans Study (GENE-FORECAST): Sodium Intervention Trial (SIT)

2021. "Genomics, Environmental Factors and Social Determinants of Cardiovascular Disease in African Americans Study (GENE-FORECAST): Sodium Intervention Trial (SIT)". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04717336.