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Vitamin

Vitamin A Compound for Non-Small Cell Lung Cancer

Q: Is this research the inaugural study of its type?

There are nine ongoing medical trials for a Vitamin A compound in eleven cities across two nations. The first study was completed in 2015 by Alkeus Pharmaceuticals, Inc. and involved one hundred and forty patients. The study reached its Phase 2 drug approval stage and, since 2015, 63 similar studies have been completed.

Q: What condition does Vitamin A Compound help to alleviate?

Vitamin A Compound is most frequently given to patients that are <a href="https://www.withpower.com/clinical-trials/vitamin-d">vitamin d</a> deficient. However, it can also be used to combat conditions such as disease, deficiency, and vitamin A deficiency with nutritional supplementation.

Q: Is this the first time Vitamin A Compound has been studied?

Currently, there are 9 different ongoing trials researching Vitamin A Compound. Of those 9, 2 are in the critical Phase 3 stage. Most of the trials for Vitamin A Compound are taking place in Somerville, <a href="https://www.withpower.com/clinical-trials/massachusetts">Massachusetts</a>; however, there are a total of 14 locations running these studies.

Phase < 1

Waitlist Available

Led By William J Petty, MD

Research Sponsored by Wake Forest University Health Sciences

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up up to 2 years

Awards & highlights

Study Summary

This trial studies the effects of high doses of Vitamin A on non-small cell lung cancer patients who are candidates for surgery.

Eligible Conditions

Non-Small Cell Lung Cancer
Lung Cancer

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ up to 2 years

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~up to 2 years

This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 2 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Presence or Absence of Germinal Centers in Resected Tissue

Secondary outcome measures

Overall Survival

Presence or Absence of Tumor Necrosis

Proportion of Germinal Centers in Lymph Nodes

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Vitamin A compoundExperimental Treatment1 Intervention

Participants receive vitamin A compound PO for 7 consecutive days in the absence of disease progression or unacceptable toxicity. Within 21 days of completing treatment, participants then undergo surgical resection.

Group II: Therapeutic Conventional SurgeryActive Control1 Intervention

Description Participants undergo surgical resection.

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Wake Forest University Health SciencesLead Sponsor

1,236 Previous Clinical Trials

1,002,904 Total Patients Enrolled

National Cancer Institute (NCI)NIH

13,646 Previous Clinical Trials

40,931,007 Total Patients Enrolled

William J Petty, MDPrincipal InvestigatorWake Forest University Health Sciences

1 Previous Clinical Trials

43 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is this research the inaugural study of its type?

"There are nine ongoing medical trials for a Vitamin A compound in eleven cities across two nations. The first study was completed in 2015 by Alkeus Pharmaceuticals, Inc. and involved one hundred and forty patients. The study reached its Phase 2 drug approval stage and, since 2015, 63 similar studies have been completed."

Answered by AI

What condition does Vitamin A Compound help to alleviate?

"Vitamin A Compound is most frequently given to patients that are vitamin d deficient. However, it can also be used to combat conditions such as disease, deficiency, and vitamin A deficiency with nutritional supplementation."

Answered by AI

Is this the first time Vitamin A Compound has been studied?

"Currently, there are 9 different ongoing trials researching Vitamin A Compound. Of those 9, 2 are in the critical Phase 3 stage. Most of the trials for Vitamin A Compound are taking place in Somerville, Massachusetts; however, there are a total of 14 locations running these studies."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

High Dose Vitamin A Compound in Treating Participants With Resectable Non-Small Cell Lung Cancer

2019. "High Dose Vitamin A Compound in Treating Participants With Resectable Non-Small Cell Lung Cancer". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03870529.