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FET PET/MRI Imaging for Pediatric Brain Cancer
Phase < 1
Waitlist Available
Led By Jonathan McConathy, MD, PhD
Research Sponsored by University of Alabama at Birmingham
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be younger than 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 2 years
Awards & highlights
Study Summary
This trial is testing whether adding PET/MRI to standard MRI will change the surgical plan for patients with cancer and whether it can detect residual tumor after surgery.
Who is the study for?
This trial is for children under 18 with a known or suspected primary brain tumor that's planned to be surgically removed. The tumor must show on an MRI and have a certain size. Kids should be expected to live more than 8 weeks, not pregnant, and able to undergo the FET-PET/MRI scan without sedation.Check my eligibility
What is being tested?
The study tests if using FET-PET/MRI imaging changes surgical plans compared to just MRI, and checks if this advanced imaging can detect any leftover tumor after surgery. It also looks at how pre- and post-surgery images might predict the time before the tumor comes back.See study design
What are the potential side effects?
There are no direct side effects mentioned for FET-PET/MRI in this summary; however, general risks may include discomfort from lying still during scans, exposure to radiation from PET scans, and potential allergic reactions to contrast agents used in MRIs.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ 2 years
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~2 years
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Percentage of patients who have residual tumor after surgery detected with FET-PET/MRI
Percentage of patients whose surgical plan change with FET-PET/MRI compared to MRI alone.
Trial Design
1Treatment groups
Experimental Treatment
Group I: FET-PET/MRIExperimental Treatment1 Intervention
O-(2-[F-18]FET)-L-tyrosine (FET) for brain PET/MRI
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Who is running the clinical trial?
University of Alabama at BirminghamLead Sponsor
1,579 Previous Clinical Trials
2,275,958 Total Patients Enrolled
Jonathan McConathy, MD, PhDPrincipal InvestigatorUniversity of Alabama at Birmingham
4 Previous Clinical Trials
168 Total Patients Enrolled
Media Library
Eligibility Criteria:
This trial includes the following eligibility criteria:- The tumor has specific characteristics seen on an MRI scan.You have never had cancer that has spread to your brain.You have a brain tumor that doesn't show up on imaging with contrast dye, and you are planning to have standard surgery to remove it.Your tumor can be measured and is larger than 1 centimeter in two different directions on an MRI scan.You need to be able to have a scan without needing medicine to help you relax.
Research Study Groups:
This trial has the following groups:- Group 1: FET-PET/MRI
Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Does this investigation include geriatric participants?
"This trial mandates that potential participants are between 6 and 18 years old, as indicated by the eligibility requirements."
Answered by AI
Are there any current opportunities for individuals to join this medical experiment?
"Clinicaltrials.gov states that this investigation is not accepting participants at the present moment. Posting first on April 23, 2018 and last edited June 7, 2022 there are no active recruitment efforts for this trial; however, 402 other studies have open enrollment currently available."
Answered by AI
Does my profile meet the criteria for inclusion in this research project?
"This clinical trial seeks out one individual aged 6 to 18 with brain cancer who meets the following criteria: a primary non-enhancing tumor requiring surgery, youthful age at enrollment (18 years old or younger), and 8 weeks of remaining life expectancy."
Answered by AI
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