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Estrogen

Transdermal Estradiol for Transgender

Phase < 1
Waitlist Available
Led By Jenna Sarvaideo, DO
Research Sponsored by Medical College of Wisconsin
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 8 months
Awards & highlights

Study Summary

This trial is testing which form of estradiol results in the least coagulation system activation in transgender women.

Eligible Conditions
  • Transgender
  • Blood Clotting Disorder

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~8 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and 8 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Coagulation system activation and fibrinolysis due to estradiol administration
Secondary outcome measures
Thrombotic risk due to estradiol administration

Trial Design

3Treatment groups
Active Control
Group I: Transdermal EstradiolActive Control1 Intervention
Transdermal estradiol administered for 8 weeks
Group II: Sublingual EstradiolActive Control1 Intervention
Sublingual estradiol administered for 8 weeks
Group III: Oral EstradiolActive Control1 Intervention
Oral estradiol administered for 8 weeks

Find a Location

Who is running the clinical trial?

Medical College of WisconsinLead Sponsor
609 Previous Clinical Trials
1,162,577 Total Patients Enrolled
1 Trials studying Transgender
90 Patients Enrolled for Transgender
Jenna Sarvaideo, DOPrincipal InvestigatorMedical College of Wisconsin

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there any vacancies available for this clinical test?

"According to the clinicaltrials.gov website, this medical trial is currently recruiting patients for participation. The initial posting took place on December 7th 2021 and the latest edit occured last month on September 29th 2022."

Answered by AI

How many participants are being included in this experiment?

"Affirmative. According to the information on clinicaltrials.gov, this medical study was first published in December 2021 and has recently been updated in September 2022. The trial is actively recruiting 10 participants from 1 location for participation."

Answered by AI

Who else is applying?

What state do they live in?
Arkansas
What portion of applicants met pre-screening criteria?
Did not meet criteria
Met criteria
How many prior treatments have patients received?
0
What site did they apply to?
Froedtert Hospital

Why did patients apply to this trial?

I wish to contribute and help other transgender people.
PatientReceived 2+ prior treatments
Recent research and studies
clinicaltrials.govStudy
Coagulation and Fibrinolysis of Estradiol in Transwomen
Jenna Sarvaideo 2021. "Coagulation and Fibrinolysis of Estradiol in Transwomen". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05387577.
~2 spots leftby Apr 2025
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