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Antioxidant

Young controls for Aging

Phase < 1
Waitlist Available
Led By R V Sekhar, MD
Research Sponsored by Rajagopal V Sekhar
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up each subject will be studied over 4 months
Awards & highlights

Study Summary

This trial will help determine if elderly humans have diminished synthesis of glutathione in the skeletal muscle, and if this can be improved by supplementing cysteine and glycine in the diet.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~each subject will be studied over 4 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and each subject will be studied over 4 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Muscle glutathione concentration

Trial Design

3Treatment groups
Active Control
Placebo Group
Group I: Young controlsActive Control1 Intervention
Young controls will be studied before and after receiving cysteine and glycine for 2 weeks
Group II: Elderly activeActive Control1 Intervention
Elderly subjects in the active group will receive glycine plus cysteine (as n-acetylcysteine) for 4 months, and be studied at baseline, 2 weeks and 4 months
Group III: Elderly placeboPlacebo Group1 Intervention
Elderly subjects in the placebo group will receive alanine for 4 months, and be studied at baseline, 2 weeks and 4 months

Find a Location

Who is running the clinical trial?

Rajagopal V SekharLead Sponsor
National Institute on Aging (NIA)NIH
1,672 Previous Clinical Trials
28,018,627 Total Patients Enrolled
160 Trials studying Aging
75,971 Patients Enrolled for Aging
R V Sekhar, MDPrincipal InvestigatorBaylor College of Medicine
1 Previous Clinical Trials
10 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Glutathione and Fuel Oxidation in Aging
Rajagopal V Sekhar 2013. "Glutathione and Fuel Oxidation in Aging". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT01870193.
~3 spots leftby Apr 2025
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