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Diuretic

Amiloride for Pharmacokinetics

Phase < 1
Waitlist Available
Led By Venkata K Yellepeddi, PhD
Research Sponsored by University of Utah
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 24 hours
Awards & highlights

Study Summary

This trial tests how well a nasal spray containing amiloride is absorbed by the body, in healthy volunteers.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~24 hours
This trial's timeline: 3 weeks for screening, Varies for treatment, and 24 hours for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
amiloride plasma concentration

Trial Design

3Treatment groups
Experimental Treatment
Group I: 0.6 mgExperimental Treatment1 Intervention
Group II: 0.4 mgExperimental Treatment1 Intervention
Group III: 0.2 mgExperimental Treatment1 Intervention
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Amiloride
2013
Completed Phase 4
~920

Find a Location

Who is running the clinical trial?

Center for Addiction and Mental HealthUNKNOWN
1 Previous Clinical Trials
12,500 Total Patients Enrolled
University of UtahLead Sponsor
1,094 Previous Clinical Trials
1,775,502 Total Patients Enrolled
1 Trials studying Pharmacokinetics
12 Patients Enrolled for Pharmacokinetics
Venkata K Yellepeddi, PhDPrincipal InvestigatorUniversity of Utah

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does this research initiative accept elderly volunteers?

"Patients aged between 18 and 30 years old are eligible to be included in this clinical trial."

Answered by AI

Could you please describe any previous experiments involving Amiloride?

"Currently, seven clinical trials are being conducted in relation to Amiloride. Of these studies, two are classified as Phase 3 while the remainder is taking place primarily Salt Lake City with an additional six sites participating globally."

Answered by AI

How many individuals are receiving treatment through this investigation?

"As of 11/1/2022, this particular clinical trial has concluded its recruitment process. The investigation was originally posted on 9/28/2020 and no longer requires participants. However, 39 medical trials concerning pharmacokinetics are currently recruiting patients as well as 7 Amiloride-related studies with open enrollment slots."

Answered by AI

In which medical scenarios is Amiloride prescribed?

"Commonly used to regulate elevated blood pressure, amiloride has also been prescribed as a therapeutic measure for nephrolithiasis, congestive heart failure (CHF), and polyuria."

Answered by AI

Who meets the criteria to participate in this experiment?

"Prospective participants of this study must demonstrate proficiency in pharmacokinetics and be between the ages 18 to 30. The number of people accepted is limited to 15 individuals."

Answered by AI

Is this experiment actively looking for participants right now?

"This clinical trial is now closed. It began recruitment on September 28th 2020 and the last update was posted November 1st 2022. If you are looking for other trials, there are currently 39 different studies searching for participants with pharmacokinetics experience, as well as 7 research studies actively accepting candidates to participate in experiments involving Amiloride."

Answered by AI
Recent research and studies
~3 spots leftby Apr 2025