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Preservative free Chloroprocaine Group 1 for Cesarean Section (CLOR-PRO Trial)

Phase < 1
Waitlist Available
Led By Brandon M Togioka, MD
Research Sponsored by Oregon Health and Science University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 1 minute after intraperitoneal chloroprocaine administration
Awards & highlights

CLOR-PRO Trial Summary

This trial is testing whether chloroprocaine can be used as an alternative to general anesthesia during cesarean delivery, to reduce mother's discomfort from surgical pain and improve the birth experience.

CLOR-PRO Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~1 minute after intraperitoneal chloroprocaine administration
This trial's timeline: 3 weeks for screening, Varies for treatment, and 1 minute after intraperitoneal chloroprocaine administration for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Chloroprocaine plasma concentration at 1 minute
Chloroprocaine plasma concentration at 10 minutes
Chloroprocaine plasma concentration at 20 minutes
+2 more
Secondary outcome measures
Adverse Events

CLOR-PRO Trial Design

3Treatment groups
Active Control
Group I: Preservative free Chloroprocaine Group 1Active Control1 Intervention
40 ml of preservative-free 1% chloroprocaine
Group II: Preservative free Chloroprocaine Group 2Active Control1 Intervention
40 ml of preservative-free 2% chloroprocaine
Group III: Preservative free Chloroprocaine Group 3Active Control1 Intervention
40 ml of preservative-free 3% chloroprocaine

Find a Location

Who is running the clinical trial?

Oregon Health and Science UniversityLead Sponsor
973 Previous Clinical Trials
7,385,797 Total Patients Enrolled
Brandon M Togioka, MDPrincipal InvestigatorOregon Health and Science University
7 Previous Clinical Trials
1,037 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is this a new or existing study?

"Research into Preservative free Chloroprocaine Group 1 began in 2019 with the first clinical trial being sponsored by Sintetica SA. This initial study had 174 participants and was followed by Phase 2 drug approval. Now, there are 3 ongoing trials across 6 international locations."

Answered by AI

If a person is over the age of 20, can they participate in this research?

"This particular clinical trial is only eligible for people aged 18-50. There are 1 other trials for those under the age of 18 and 7 for seniors above 65."

Answered by AI

Does this trial have specific entry requirements in terms of age or health condition?

"The eligibility requirements for this research study include being between 18-50 years of age and having a cesarean section. Only 15 participants will be accepted in total."

Answered by AI

What medical ailment does Preservative free Chloroprocaine Group 1 commonly address?

"Chloroprocaine Group 1, which does not contain preservatives, can be used to numb an area for surgery or other medical procedures. This medication can also effectively treat conditions like infiltration and caudal epidural block therapy."

Answered by AI

Are there any other scientific papers that have investigated Preservative free Chloroprocaine Group 1?

"Chloroprocaine Group 1 has 0 trials in its final stage of development, but there are 3 clinical studies underway. Most of these research projects are based out of Rome, Italy; however, there are 9 total locations running Preservative free Chloroprocaine Group 1 clinical trials."

Answered by AI

Are we still able to enroll patients in this research program?

"This study is not recruiting patients at the moment, according to clinicaltrials.gov. The study was originally posted on 9/30/2019, and was last edited on 4/20/2022. Although this specific trial isn't looking for participants right now, there are 20 other studies that are actively recruiting patients."

Answered by AI

How many people are eligible to participate in this clinical trial?

"Unfortunately, this trial is not currently enrolling patients. It was initially posted on September 30th, 2019 but the most recent update occurred on April 20th, 2022. For individuals who are seeking other studies, there are 17 trials related to cesarean section and 3 Preservative free Chloroprocaine Group 1 that are still looking for participants."

Answered by AI
~3 spots leftby Apr 2025