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MRI for Normal Physiology

Phase < 1
Waitlist Available
Led By Dardo G Tomasi, Ph.D.
Research Sponsored by National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up end of study
Awards & highlights

Study Summary

This trial is testing whether MRI can accurately show patterns of brain function. It will compare MRI methods performed on the same day and brain function using PET scans. Eligible participants must be healthy volunteers at least 18 years old.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~end of study
This trial's timeline: 3 weeks for screening, Varies for treatment, and end of study for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
The overarching goal of this study is to quantify the reproducibility of multiple measures of brain functional connectivity (FC) during resting conditions and during task performance.
Secondary outcome measures
The association between IFCD and the underlying structural connectivity and its contribution to between- subjects FC-variability during RS.
The correlation between glucose metabolism, CBF, lFCD, C, L and S and its contribution to between- subjects FC-variability during RS.
The correlation between physiologic noise and FC measures (lFCD, C, L and S) and its contribution to within- subjects FC-variability during RS and TS conditions.
+1 more

Trial Design

1Treatment groups
Experimental Treatment
Group I: PET FDG &amp; MRI ScansExperimental Treatment2 Interventions
The test-retest reproducibility of the gender and aging effects on FC measures (lFCD, C, L and S) acquired in RS and TS conditions.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
F-18FDG
2015
Completed Early Phase 1
~120
MRI
2009
Completed Phase 2
~1370

Find a Location

Who is running the clinical trial?

National Institute on Alcohol Abuse and Alcoholism (NIAAA)Lead Sponsor
801 Previous Clinical Trials
1,365,173 Total Patients Enrolled
5 Trials studying Normal Physiology
1,939 Patients Enrolled for Normal Physiology
Dardo G Tomasi, Ph.D.Principal InvestigatorNational Institute on Alcohol Abuse and Alcoholism (NIAAA)
2 Previous Clinical Trials
217 Total Patients Enrolled
2 Trials studying Normal Physiology
217 Patients Enrolled for Normal Physiology

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is enrollment in this research endeavor still available to participants?

"Indeed, the evidence on clinicaltrials.gov suggests that this trial is still enrolling participants. It was initially posted to the website on June 8th 2015 and has been recently updated November 19th of 2022. 180 individuals will be accepted from two different medical centres for this study."

Answered by AI

How many participants have signed up for the research project thus far?

"Affirmative, clinicaltrials.gov states that this experiment is currently seeking out eligible individuals. It was originally posted on June 8th 2015 and the most recent update happened on November 19th 2022. The trial needs to recruit 180 participants from two different sites."

Answered by AI
Recent research and studies
clinicaltrials.govStudy
Reliability of the Human Brain Connectome
2015. "Reliability of the Human Brain Connectome". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT02193425.
~11 spots leftby Apr 2025
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