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Procedure

Photodynamic Therapy for Photodynamic Therapy

Phase < 1
Waitlist Available
Led By Jeffrey B Travers, MD, PhD
Research Sponsored by Jeffrey B. Travers, MD, PhD
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up day 2
Awards & highlights

Study Summary

This study is evaluating whether a cream containing an antidepressant may help counteract the effects of photodynamic therapy.

Eligible Conditions
  • Photodynamic Therapy
  • Microvesicle Particle

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~day 2
This trial's timeline: 3 weeks for screening, Varies for treatment, and day 2 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Body Weight Changes
Change in Microvesicle Particle Levels From Baseline with Photodynamic Therapy.
Secondary outcome measures
Change in Erythema From Baseline Due to Photodynamic Therapy
Change in Itch From Baseline Due to Photodynamic Therapy
Change in Skin Pain From Baseline Due to Photodynamic Therapy

Side effects data

From 2012 Phase 2 trial • 73 Patients • NCT00217087
32%
Photosensitivity
16%
Dysphagia
5%
heart attack resulting in death
3%
Respitory Failure / Sepsis
3%
Bleeding
3%
Dehydration
3%
Pain
3%
Renal failure - Sepsis
100%
80%
60%
40%
20%
0%
Study treatment Arm
Photodynamic Therapy
Endoscopic Mucosl Resection

Trial Design

2Treatment groups
Experimental Treatment
Group I: 4% Imipramine Cream on Upper Forearm SiteExperimental Treatment3 Interventions
Base cream will be applied to the lower forearm site.
Group II: 4% Imipramine Cream on Lower Forearm SiteExperimental Treatment3 Interventions
Base cream will be applied to the upper forearm site.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Photodynamic Therapy
2014
Completed Phase 4
~460

Find a Location

Who is running the clinical trial?

Jeffrey B. Travers, MD, PhDLead Sponsor
4 Previous Clinical Trials
156 Total Patients Enrolled
Wright State UniversityLead Sponsor
41 Previous Clinical Trials
54,882 Total Patients Enrolled
Jeffrey B Travers, MD, PhDPrincipal InvestigatorWright State Physicians
9 Previous Clinical Trials
260 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Photodynamic Therapy and Microvesicles
Jeffrey B. Travers, MD, PhD 2021. "Photodynamic Therapy and Microvesicles". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03960125.
~0 spots leftby Apr 2025
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