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Anticoagulant

Normal Saline Group for Cancer

Phase < 1
Waitlist Available
Led By Meredith C Allen, BSN
Research Sponsored by University of Texas Southwestern Medical Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up from day 1 and up to day 7 of enrollment
Awards & highlights

Study Summary

This trial is testing whether using Normal Saline Flushes instead of Heparin Flushes to keep central lines open is just as effective in preventing line occlusion.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~from day 1 and up to day 7 of enrollment
This trial's timeline: 3 weeks for screening, Varies for treatment, and from day 1 and up to day 7 of enrollment for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Patency
Secondary outcome measures
Infection Rate

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Normal Saline GroupExperimental Treatment1 Intervention
Participants will receive only Normal Saline for PICC line maintenance. All lumens of PICC line will be flushed every 24 hours with 10cc Normal Saline. PICC line will be flushed with 10cc Normal Saline after administration of medication, blood products, or blood draws.
Group II: Heparin GroupActive Control1 Intervention
Participants will receive the UTSW standard of of care for PICC line maintenance. All lumens of PICC line will be flushed w/ Heparin Flush every 8 hours. PICC line will be flushed with 10cc Normal Saline followed by 3cc Heparin Flush after administration of medication, blood products, or blood draws.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Normal Saline Group
2020
Completed Early Phase 1
~150

Find a Location

Who is running the clinical trial?

University of Texas Southwestern Medical CenterLead Sponsor
1,047 Previous Clinical Trials
1,053,657 Total Patients Enrolled
Miriam GonzalesStudy ChairUniversity of Texas Southwestern Medical Center
Kavitha NairStudy ChairUniversity of Texas Southwestern Medical Center

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Am I eligible to take part in this medical experiment?

"This medical trial is accepting 175 participants, ranging in age from 18 to 80. Applicants must have a PICC line placed pre-operatively or post-operatively and are admitted to the Bone Marrow Transplant Unit at Clements University Hospital University of Texas Southwestern Medical Center. Additionally, they must be capable of performing flushes without difficulty."

Answered by AI

Could you elaborate on the prior research done using Normal Saline Group?

"Currently, 36 studies are underway to explore Normal Saline Group. Of these trials, 12 have entered Phase 3. While the majority of operations for this treatment occur in Sherbrooke, Quebec, 367 other sites around the globe are also running tests with it."

Answered by AI

What are the therapeutic benefits of Normal Saline Group?

"Normal Saline Group is a medical treatment used for the care of equipment, as well as sprains, atrial fibrillation and unstable angina pectoris."

Answered by AI

Does this medical study permit those over the age of sixty-five to participate?

"For this trial to be accessible, patients must fall between the age parameters of 18 and 80. Alternatively, there are 65 studies for minors (underage) individuals, as well as 465 research opportunities open to seniors (overaged)."

Answered by AI

Has there been any precedent for this research endeavor?

"Presently, 36 live trials of Normal Saline Group exist in 197 locales across 21 countries. In 2006, Ash Access Technology initiated the first clinical trial with 415 volunteers and successfully achieved Phase 3 drug approval status. Since then, 189 more studies have materialised."

Answered by AI

Are there any vacancies available in this research endeavor?

"Per the details listed on clinicaltrials.gov, this experiment is currently accepting participants. The posting was initiated on February 12th 2020 and revised most recently on August 29th 2022."

Answered by AI

What is the scope of involvement in this clinical investigation?

"Yes, according to the information on clinicaltrials.gov, this research is open for enrollment. It was initially announced on February 12th 2020 and its details were last modified on August 29th 2022. The investigators are looking to recruit 175 volunteers from a single site."

Answered by AI
Recent research and studies
clinicaltrials.govStudy
Heparin Versus Normal Saline in Peripherally Inserted Central Catheter Lines
Meredith Allen 2020. "Heparin Versus Normal Saline in Peripherally Inserted Central Catheter Lines". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05029596.
~27 spots leftby Apr 2025
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