Thallous Chloride Tl 201

Planar Scintigraphy, Single photon emission computerised tomography, Parathyroid gland + 4 more
Treatment
8 FDA approvals
20 Active Studies for Thallous Chloride Tl 201

What is Thallous Chloride Tl 201

Thallous chlorideThe Generic name of this drug
Treatment SummaryThallous chloride (also known as thallium(I) chloride) is a colorless powder used to isolate thallium from its ores. This powder is made by mixing thallium(I) sulfate with hydrochloric acid. It is used as a diagnostic radiopharmaceutical to diagnose heart and parathyroid problems. Side effects may include blurred vision, chest pain, chills, confusion, coughing, difficulty breathing or swallowing, and dizziness.
Thallous Chloride Tl 201is the brand name
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Thallous Chloride Tl 201 Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Thallous Chloride Tl 201
Thallous chloride
1977
5

Approved as Treatment by the FDA

Thallous chloride, commonly known as Thallous Chloride Tl 201, is approved by the FDA for 8 uses which include Single photon emission computerised tomography and Myocardial Ischemia .
Single photon emission computerised tomography
Myocardial Ischemia
Exercise electrocardiogram
Ischemic Heart Disease
Heart Attack
Coronary Artery Disease
Parathyroid gland
Planar Scintigraphy

Effectiveness

How Thallous Chloride Tl 201 Affects PatientsNo information available.
How Thallous Chloride Tl 201 works in the bodyThallous Chloride TI201 is a substance that collects in the heart like potassium does. When this substance is used during imaging tests, it can show areas of damage or blockage in the heart. It can also show areas where not enough blood is flowing to the heart. Sometimes, the right coronary artery may be hard to spot due to its shape.

When to interrupt dosage

The proposed dosage of Thallous Chloride Tl 201 is contingent upon the diagnosed condition, such as Single photon emission computerised tomography, Ischemic Heart Disease and Planar Scintigraphy. The quantity of dosage is dependent on the approach of delivery (e.g. Injection, powder, lyophilized, for solution or Injection, solution - Intravenous) stated in the following table.
Condition
Dosage
Administration
Parathyroid gland
1.0 mCi/mL, , 2.0 mCi/mL
, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous
Planar Scintigraphy
1.0 mCi/mL, , 2.0 mCi/mL
, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous
Exercise electrocardiogram
1.0 mCi/mL, , 2.0 mCi/mL
, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous
Single photon emission computerised tomography
1.0 mCi/mL, , 2.0 mCi/mL
, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous
Heart Attack
1.0 mCi/mL, , 2.0 mCi/mL
, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous
Myocardial Ischemia
1.0 mCi/mL, , 2.0 mCi/mL
, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous
Coronary Artery Disease
1.0 mCi/mL, , 2.0 mCi/mL
, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous

Warnings

Common Thallous Chloride Tl 201 Drug Interactions
Drug Name
Risk Level
Description
Thallous Chloride Tl 201 Toxicity & Overdose RiskThe lethal dose of thallium for a mouse is 24mg per kilogram, and for a human is 8mg per kilogram. Unknown biochemical damage is caused by thallium, but it is known to lead to paralysis and cardiovascular problems. Death typically occurs due to respiratory failure or cardiac arrest.
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Thallous Chloride Tl 201 Novel Uses: Which Conditions Have a Clinical Trial Featuring Thallous Chloride Tl 201?

145 active clinical trials are being conducted to investigate the potential of Thallous Chloride Tl 201 to ameliorate Ischemic Heart Disease, Parathyroid gland Dysfunction and Myocardial Ischemia.
Condition
Clinical Trials
Trial Phases
Myocardial Ischemia
4 Actively Recruiting
Not Applicable, Phase 1
Single photon emission computerised tomography
0 Actively Recruiting
Planar Scintigraphy
0 Actively Recruiting
Parathyroid gland
0 Actively Recruiting
Coronary Artery Disease
2 Actively Recruiting
Phase 1, Phase 4
Exercise electrocardiogram
0 Actively Recruiting
Heart Attack
23 Actively Recruiting
Not Applicable, Phase 1, Phase 4, Phase 2, Early Phase 1, Phase 3

Thallous Chloride Tl 201 Reviews: What are patients saying about Thallous Chloride Tl 201?

4Patient Review
10/18/2010
Thallous Chloride Tl 201 for Medication to Aid Study of the Blood Flow in the Heart
I was originally having chest pain, which led to an abnormal EKG. As a result, my doctor ordered a treadmill stress test.
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Patient Q&A Section about thallous chloride tl 201

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is Thallous chloride used for?

"Thallous chloride Tl 201 injection is a radioactive medicine that helps doctors diagnose heart disease in adults. The injection is given during a procedure called planar scintigraphy or single-photon emission computed tomography (SPECT)."

Answered by AI

What are the dangers of thallium-201?

"Other reported events from taking this medication include itching, nausea/vomiting, mild diarrhea, tremor, shortness of breath, chills, fever, conjunctivitis, sweating, and blurred vision."

Answered by AI

Where does thallium-201 come from?

"Thallium-201 is a radiopharmaceutical used for scintigraphy, primarily of the myocardium. Thallium is treated by the body as an analog of potassium. It is produced in a cyclotron by bombarding thallium-203 with protons."

Answered by AI

Why is thallium-201 used?

"A thallium-201 scan is a radiopharmaceutical agent used to diagnose coronary artery disease and parathyroid hyperactivity. Other potential uses for a thallium-201 scan, such as tumor diagnosis and olfacto-scintigraphy, are being researched and have shown promising results in various studies."

Answered by AI

Clinical Trials for Thallous Chloride Tl 201

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Remote Home Monitoring for Heart Attack

18+
All Sexes
Winnipeg, Canada
Heart attacks are one of the top causes of death in Canada, with over 2,100 cases treated each year in Manitoba. Even though hospital care has improved, the period after going home is still risky. Many patients feel anxious and unsure about their recovery, and without enough support, they often end up back in the emergency department (ED). This is an even bigger challenge for people in rural areas, where getting follow-up care can be much harder. Filling these gaps is important to help patients get better and to reduce stress on the healthcare system. In a previous study, the investigators found that extra support made a big difference: only 8% of participants using a digital health tool returned to the ED within 30 days, compared to 22% of participants without it. Now, the investigators want to expand this study across Manitoba to see if digital health tools can help more people recover safely at home. The investigators will compare two types of follow-up care: education only versus education with extra support (like symptom tracking and virtual appointments). The investigators will look at how this affects hospital visits, mental well-being, and healthcare costs. The goal is to create a better support system for people after a heart attack, leading to healthier recoveries, less strain on hospitals, and better care for Manitobans - no matter where they live.
Waitlist Available
Has No Placebo
St Boniface Hospital
Image of Baystate Medical Center in Springfield, United States.

Consent Approaches for Heart Disease Rehabilitation

18+
All Sexes
Springfield, MA
Cardiac Rehabilitation is a lifestyle and exercise program for patients with heart disease. Cardiac Rehabilitation is strongly recommended in guidelines, but only 30% of eligible patients attend. New strategies are needed to help more patients attend cardiac rehabilitation. In this study, the investigators will see if using an $50 incentive, case management, text messages, and physical activity coaching combined into a single intervention will help more patients attend cardiac rehabilitation. In preparation for a larger trial, patients will also be randomly assigned to four different ways of seeking their permission to be in a research study. The investigators will see if these approaches affect how many people participate in the research project. The two main goals of this study is to understand: 1. If the consent approach type impacts participation rates in the research study 2. If the multi-component intervention (case management, financial incentives, text messages, and physical activity coaching) improves cardiac rehabilitation participation within 3 months.
Recruiting
Has No Placebo
Baystate Medical CenterQuinn R Pack, MD, MSc
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Carbetocin for C-section

18+
Female
Kingston, Canada
The goal of this project is to examine the cardiac symptoms and physiologic changes after administration of a reduced dose of carbetocin in participants undergoing elective cesarian section. * Does reduced dose carbetocin (50mcg) have fewer cardiac side effects than usual dose carbetocin (100mcg) when comparing patient reported symptoms, ECG changes and troponin increases? * Is there a relationship between patient reported cardiac symptoms after carbetocin administration and subjective measures of cardiac ischemia (ECG changes and troponin increases? Researchers will compare 50mcg of carbetocin to the control group of 100mcg of carbetocin in patients undergoing elective cesarian section. Participants will: * Be given 50mcg or 100mcg of carbetocin during cesarian section * Asked to report cardiac symptoms * Be assessed for ECG changes and blood loss using standard of practice monitoring * Have a troponin I blood test completed after delivery
Phase 4
Waitlist Available
Kingston Health Sciences CentreJordan Leitch, MD
Have you considered Thallous Chloride Tl 201 clinical trials? We made a collection of clinical trials featuring Thallous Chloride Tl 201, we think they might fit your search criteria.Go to Trials
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Orticumab for Heart Attack

18+
All Sexes
Los Angeles, CA
The goal of this clinical trial is to determine the clinical effect of orticumab treatment on inflammation in study participants with prior myocardial infarction who have elevated coronary inflammation based on CCTA. The main question it aims to answer is: Clinical effects of orticumab treatment on inflammation of the coronary artery parameters measured with CCTA Researchers will compare the effects with placebo group after 6 months of treatment Participants will Keep the planned study visit appointments Provide complete information about medical and medical history Speak to the study doctor before changing any of non-study treatments, including starting new medications, receiving any vaccinations, or setting out to join any other clinical studies
Phase 2
Recruiting
Abcentra Investigational Site (+6 Sites)Abcentra
Image of The Ohio State University Wexner Medical Center in Columbus, United States.

Health Coaching for Cardiovascular Disease

18+
All Sexes
Columbus, OH
For patients discharged with a diagnosis of cardiovascular disease coronary artery disease resulting in myocardial infarction and/or congestive heart failure, this study will evaluate if the addition of 12 virtual health coaching sessions over the course of 16 weeks will improve physiological, psychological, and social health outcomes, prove acceptable and satisfactory for these patients with CVD, decrease CVD-related questions and concerns sent to the provider via MyChart, and reduce hospital readmission rates over a 90-day period as compared to patients discharged with the same diagnosis who receive standard post-discharge care. The study will also evaluate the perceptions of physician and advanced practice providers related to the health coach as part of the interprofessional team and the amount of time spent addressing CVD-related patient questions and concerns via MyChart messages.
Waitlist Available
Has No Placebo
The Ohio State University Wexner Medical CenterBeth Steinberg, PhD, RN
Have you considered Thallous Chloride Tl 201 clinical trials? We made a collection of clinical trials featuring Thallous Chloride Tl 201, we think they might fit your search criteria.Go to Trials
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Coronary Dilatation Catheter for Heart Disease

18+
All Sexes
Miami, FL
A prospective, open label, multi-center, single arm, observational study designed to evaluate the acute safety and device performance of the Sapphire 3 0.85, 1.0 and 1.25mm diameter coronary dilatation catheter in predilatation of Chronic Total Occlusion (CTO) lesions during percutaneous coronary intervention. One hundred seventy (170) subjects will be enrolled with a target of one hundred fifty-three (153) evaluable subjects by the angiographic core laboratory at up to 15 clinical sites with the Sapphire 3 0.85, 1.0 and 1.25mm diameter PTCA dilatation catheter to pre-dilate CTO lesions in coronary arteries during their index procedure. All subjects will be screened according to the protocol inclusion and exclusion criteria and will be followed through study completion, which is defined as 24-hours post-procedure or hospital discharge, whichever comes first.
Recruiting
Has No Placebo
University of Miami (+12 Sites)David Kandzari, MDOrbusNeich
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BI 765845 for Heart Attack

18+
All Sexes
Quebec, Canada
This study is open to adults aged 18 and over who have just had a heart attack. The purpose of this study is to find out whether a medicine called BI 765845 helps people who have had a heart attack. The investigators also want to test how well different doses of BI 765845 work and how they are tolerated by people who have had a heart attack. Participants are randomly assigned to receive either BI 765845 or placebo. Placebo treatments look like BI 765845 treatments but do not contain any medicine. Participants are about 3 times as likely to receive BI 765845 than placebo. Participants are in the study for 3 months. During this time, they visit the study site 7 times and get 3 phone calls from the site staff. At the visits, the doctors use clinical tests to check the health of the heart. The results are compared between the BI 765845 and placebo groups to see whether the treatment works. The doctors also regularly check participants' health and take note of any unwanted effects.
Phase 2
Waitlist Available
IUCPQ (Laval University) (+15 Sites)Boehringer Ingelheim
Have you considered Thallous Chloride Tl 201 clinical trials? We made a collection of clinical trials featuring Thallous Chloride Tl 201, we think they might fit your search criteria.Go to Trials