Schizophrenia Clinical Trials in Austin

View 14 new treatments for Schizophrenia in Austin, TX, and nearby areas, such as Round Rock. Every day, Power helps hundreds of schiz patients connect with leading medical research.
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KarXT for Schizophrenia

Karuna Clinic, Austin + 1 more

This trial tests KarXT, a combination of two drugs, for people who haven't improved with their current treatment. KarXT aims to balance brain functions and reduce side effects. The study will look at improvements in health and daily life. KarXT has shown positive results in earlier tests.Show More
Recruiting
Phase 3
Est. 4 - 6 Weeks
Bruce Kinon, MD
Study Director

Long-term Safety of Iclepertin for Schizophrenia

Boehringer Ingelheim Clinic, Austin + 1 more

This study is open to adults with schizophrenia who took part in a previous CONNEX study (study 1346-0011, 1346-0012, or 1346-0013). The purpose of this study is to find out how well people with schizophrenia can tolerate a medicine called Iclepertin in the long term. Participants take Iclepertin as tablets once a day for 1 year. In addition, all participants take their normal medication for schizophrenia. Participants are in the study for a little more than 1 year. During this time, they visit the study site about 13 times and get about 9 phone calls from the study team. The doctors collect information on any health problems of the participants. Doctors also regularly check the participants' symptoms of schizophrenia.Show More
Recruiting

No Placebo Trial

Phase 3
Est. 5 - 8 Weeks
Unregistered Study Lead
Research Team

Brilaroxazine for Schizophrenia

Reviva Clinic, Austin + 1 more

This trial tests Brilaroxazine, a daily pill, in patients with severe mental health issues. It aims to improve mood and reduce symptoms. The study lasts for more than a year.Show More
Recruiting
Phase 3
Est. 4 - 6 Weeks
Medical Director
Study Director

KarXT for Schizophrenia

Karuna Clinic, Austin + 3 more

This trial tests the safety and tolerability of KarXT, a combination of two drugs, in schizophrenia patients who haven't responded well to their current treatments. KarXT aims to improve symptoms and manage side effects better than existing medications. KarXT (xanomeline plus trospium) is an emerging treatment for schizophrenia, showing promise in managing total, positive, and negative symptoms.Show More
Recruiting

No Placebo Trial

Phase 3
Est. 5 - 8 Weeks
Bristol-Myers Squibb
Study Director

Iclepertin for Schizophrenia

Boehringer Ingelheim Clinic, Austin + 1 more

This trial tests if a medicine called Iclepertin can help improve memory and learning in adults with schizophrenia. Participants take Iclepertin daily while continuing their usual medication. Doctors regularly check their mental abilities and health throughout the study. Iclepertin is being studied for its potential to improve cognitive functions in schizophrenia.Show More
Recruiting
Phase 3
Est. 3 - 6 Weeks
Unregistered Study Lead
Research Team

Valbenazine for Schizophrenia

Neurocrine Clinic, Austin + 1 more

The primary objective for this study is to evaluate the effect of adjunctive valbenazine versus placebo on symptoms of schizophrenia in participants who have inadequate response to antipsychotic treatment.Show More
Recruiting
Phase 3
Est. 6 - 12 Weeks
Clinical Development Lead
Study Director

Cariprazine for Pediatric Schizophrenia

AbbVie Clinic, Austin + 1 more

This trial is testing the safety and effectiveness of cariprazine in children and teens with schizophrenia, bipolar I disorder, or autism. The goal is to see if the medication is safe and beneficial for use in these young patients.Show More
Recruiting

No Placebo Trial

Phase 3
Est. 3 - 12 Weeks
ABBVIE INC.
Study Director

MK-8189 for Schizophrenia

Merck Sharp & Dohme Clinic, Austin + 1 more

This trial tests the effectiveness and safety of a medication called MK-8189 in adults with acute schizophrenia. The study compares different doses of the medication to see if it can better reduce symptoms. The goal is to find out if MK-8189 can help improve the condition of these patients.Show More
Recruiting
Phase 2
Est. 6 - 12 Weeks
Medical Director
Study Director

Emraclidine for Schizophrenia

Cerevel Clinic, Austin + 1 more

This trial aims to evaluate the safety and tolerability of a medication called emraclidine, taken by mouth, in adults with schizophrenia.
Recruiting

No Placebo Trial

Phase 2
Est. 3 - 6 Weeks
Erica Koenig, PhD
Study Director

Emraclidine for Schizophrenia

Cerevel Clinic, Austin + 1 more

This trial is testing a new medication called Emraclidine, given in two different doses daily. It aims to help people with schizophrenia who are having severe symptom flare-ups. The medication works by targeting specific parts of the brain to reduce symptoms like hallucinations and delusions.Show More
Waitlist
Phase 2
Est. 3 - 6 Weeks
Erica Koenig, PhD
Study Director
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Frequently Asked Questions

How much do schizophrenia clinical trials pay?

Each trial will compensate patients a different amount, but $50-100 for each visit is a fairly common range. Further, most trials will cover the costs of an Uber to-and-from the clinic. Factors that can affect compensation include the phase of the trial, the length of the trial, the frequency of visits, and the specific condition being studied.

Do I need to be insured to participate in a medical study?

Clinical trials are almost always free to participants, and so do not require insurance. The only exception here are trials focused on Cancer, because only a small part of the typical treatment plan is actually experimental. For these cancer trials, participants typically need insurance to cover all the non-experimental components.

How do schizophrenia clinical trials work?

After a researcher reviews your profile, they may choose to invite you in to a screening appointment, where they'll determine if you meet 100% of the eligibility requirements. If you do, you'll typical be sorted into one of the treatment groups, and will receive your study drug. For some trials, there is a chance you'll receive a placebo. Across schizophrenia trials in Austin, 42% of clinical trials have a placebo. Typically you'll be required to check-in with the clinic every month or two. The average trial length in this city for schizophrenia patients is 6 Months.

What does the "phase" of a clinical trial mean?

The phase of a trial reveals what stage the drug is in getting approval for a specific condition. Phase 3 trials are in the final step before approval. The drug already has data showing both safety and effectiveness. Phase 2 trials are those where the drug has some data showing safety in humans, but where effectiveness has typically only been shown in animals and non-human experiments. Phase 1 trials are the trials where we don't have safety data in humans. As a general rule, phase 3 trials are more promising than phase 2, and phase 2 trials are more promising than phase 1.

Where in Austin is research being conducted for schizophrenia?

Clinical trials for schizophrenia in Austin are being conducted by Community Clinical Research, Inc., with approximately 4 trials ongoing. These trials are concentrated in the northern part of the city as of 2024.

What promising new drugs are being tested?

In Austin, schizophrenia research is exploring treatments like Serotonin-Dopamine Activity Modulators and NMDA receptor antagonists. Notable drugs being studied include Brilaroxazine, Cariprazine, and Xanomeline with Trospium Chloride.