Arthritis Clinical Trials in Columbus
View 10 new treatments for Arthritis in Columbus, OH. Every day, Power helps hundreds of Arthritis patients connect with leading medical research.Baricitinib vs TNF Inhibitors for Rheumatoid Arthritis
Eli Lilly Clinic, Columbus + 1 more
This post-marketing study is designed to compare the safety of baricitinib versus tumor necrosis factor (TNF) inhibitors with respect to venous thromboembolic events (VTEs) when given to participants with rheumatoid arthritis.Show More
No Placebo Trial
Baricitinib for Rheumatoid Arthritis
Eli Lilly Clinic, Marion + 1 more
This trial compares the safety of two treatments for rheumatoid arthritis, focusing on the risk of blood clots. One treatment is baricitinib, an oral medication used for moderate to severe cases.Show More
No Placebo Trial
Amniotic Suspension Allograft for Knee Osteoarthritis
Organogenesis Clinic, Columbus + 1 more
This trial is testing if injecting ASA into the knee can help people with knee osteoarthritis feel better. The study will check pain levels, knee function, and safety over several months. ASA (Amniotic Suspension Allograft) has been shown to be an effective treatment for knee osteoarthritis in previous studies.Show More
Abatacept Injection for Juvenile Idiopathic Arthritis
Research Clinic, Columbus + 1 more
This is a research study to test whether a once-weekly injection of abatacept will prevent the progression of Juvenile Idiopathic Arthritis (JIA) to a more severe form. To evaluate the effectiveness of a 24-week course of treatment with abatacept plus usual care versus usual care to prevent polyarthritis (≥5 joints), uveitis, or treatment with other systemic medication within 18 months of randomization in children with recent-onset limited JIA.Show More
No Placebo Trial
ZILRETTA for Shoulder Osteoarthritis
Pacira Clinic, Columbus + 1 more
Primary Objective: To assess the efficacy of ZILRETTA on pain following an intra-articular (IA) injection in subjects with glenohumeral osteoarthritis (OA) relative to normal saline placebo Secondary Objective: * To assess the efficacy of ZILRETTA on pain following an IA injection in subjects with glenohumeral OA relative to triamcinolone acetonide injectable suspension, immediate release (TCA-IR) and normal saline placebo * To assess the safety of ZILRETTA in subjects with glenohumeral OA relative to normal saline placebo and TCA-IRShow More
Emapalumab for MAS in Still's Disease or Lupus
Swedish Orphan Biovitrum Clinic, Columbus + 1 more
This trial is testing emapalumab, a medication that helps control an overactive immune system, in children and adults with certain immune conditions who haven't responded to high-dose steroids. The goal is to see if it is safe and effective in reducing excessive inflammation. Emapalumab is a monoclonal antibody that targets interferon-γ and was first approved for treating primary hemophagocytic lymphohistiocytosis (HLH) in patients with refractory, recurrent, or progressive disease.Show More
No Placebo Trial
MFat vs Corticosteroid Injection for Knee Osteoarthritis
Lipogems Clinic, Columbus + 1 more
This trial is testing a new treatment where a patient's own fat is processed and injected into their knee to help with pain and function in people with moderate knee osteoarthritis. The goal is to see if this method works better by reducing inflammation and promoting healing. This approach has shown promising results in reducing pain and improving function.Show More
No Placebo Trial
TTAX03 Injection for Knee Osteoarthritis
Tissue Tech Clinic, Columbus + 1 more
This trial tests if a single injection of TTAX03 in saltwater can improve knee conditions better than just saltwater. It targets patients needing knee injections and checks their response over a few months.Show More
Metformin for Osteoarthritis After ACL Surgery
Research Clinic, Columbus + 1 more
This study is being done to find out if metformin is effective at reducing pain by delaying the onset of post-traumatic osteoarthritis (PTOA) after anterior cruciate ligament (ACL) reconstruction. This research study will compare metformin to placebo. The placebo tablet looks exactly like metformin, but contains no metformin. Placebos are used in research studies to see if the results are due to the study drug or due to other reasons. Metformin is approved by the U.S. Food and Drug Administration (FDA) to treat type II diabetes. Notably, it also has anti-inflammatory effects, suggesting it could benefit people who have an ACL injury and are undergoing ACL reconstruction.Show More
CartiLife® for Osteoarthritis and Articular Cartilage Injury
Biosolution Clinic, Columbus + 1 more
This trial is testing a new treatment that uses small pellets made from a patient's own cartilage cells to repair knee damage. It targets adults with knee cartilage defects caused by injury or wear and tear. The treatment aims to reduce pain and improve knee function by helping the damaged cartilage heal and regrow.Show More
No Placebo Trial
Frequently Asked Questions
How much do arthritis clinical trials pay?
Each trial will compensate patients a different amount, but $50-100 for each visit is a fairly common range. Further, most trials will cover the costs of an Uber to-and-from the clinic. Factors that can affect compensation include the phase of the trial, the length of the trial, the frequency of visits, and the specific condition being studied.
Do I need to be insured to participate in a medical study?
Clinical trials are almost always free to participants, and so do not require insurance. The only exception here are trials focused on Cancer, because only a small part of the typical treatment plan is actually experimental. For these cancer trials, participants typically need insurance to cover all the non-experimental components.
How do arthritis clinical trials work?
After a researcher reviews your profile, they may choose to invite you in to a screening appointment, where they'll determine if you meet 100% of the eligibility requirements. If you do, you'll typical be sorted into one of the treatment groups, and will receive your study drug. For some trials, there is a chance you'll receive a placebo. Across arthritis trials in Columbus, 42% of clinical trials have a placebo. Typically you'll be required to check-in with the clinic every month or two. The average trial length in this city for arthritis patients is 6 Months.
What does the "phase" of a clinical trial mean?
The phase of a trial reveals what stage the drug is in getting approval for a specific condition. Phase 3 trials are in the final step before approval. The drug already has data showing both safety and effectiveness. Phase 2 trials are those where the drug has some data showing safety in humans, but where effectiveness has typically only been shown in animals and non-human experiments. Phase 1 trials are the trials where we don't have safety data in humans. As a general rule, phase 3 trials are more promising than phase 2, and phase 2 trials are more promising than phase 1.
Where in Columbus is research being conducted for arthritis?
Prominent hospitals in Columbus conducting arthritis clinical trials include Nationwide Children's Hospital and The Ohio State University. Approximately 12 trials are ongoing as of 2024, primarily centered around the university area.
What promising new drugs are being tested?
In Columbus, arthritis research includes treatments like Implants, Prostheses, and Cell Therapy. Notable specific interventions being studied are the Agili-C Implant, Baricitinib, and Abatacept Injection.