Nancy Y. Lee, MD, FASTRO - MSK ...

Dr. Nancy Lee, MD

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Memorial Sloan Kettering Cancer Center

Studies Head and Neck Cancers
Studies Squamous Cell Carcinoma
14 reported clinical trials
31 drugs studied

Area of expertise

1

Head And Neck Cancers

Nancy Lee, MD has run 5 trials for Head and Neck Cancers.

2

Squamous Cell Carcinoma

Nancy Lee, MD has run 4 trials for Squamous Cell Carcinoma. Some of their research focus areas include:

Stage III
Stage IV
p16 negative

Affiliated Hospitals

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Memorial Sloan Kettering Cancer Center

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Memorial Sloan Kettering Cancer Center (All Protocol Activities)

Clinical Trials Nancy Lee, MD is currently running

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Chemotherapy + Radiation Therapy

for Head and Neck Cancer

This phase II/III trial studies how well radiation therapy works when given together with cisplatin, docetaxel, cetuximab, and/or atezolizumab after surgery in treating patients with high-risk stage III-IV head and neck cancer the begins in the thin, flat cells (squamous cell). Specialized radiation therapy that delivers a high dose of radiation directly to the tumor may kill more tumor cells and cause less damage to normal tissue. Drugs used in chemotherapy, such as cisplatin and docetaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Cetuximab is a monoclonal antibody that may interfere with the ability of tumor cells to grow and spread. Immunotherapy with monoclonal antibodies, such as atezolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. The purpose of this study is to compare the usual treatment (radiation therapy with cisplatin chemotherapy) to using radiation therapy with docetaxel and cetuximab chemotherapy, and using the usual treatment plus an immunotherapy drug, atezolizumab.

Recruiting

1 award

Phase 2 & 3

21 criteria

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Personalized Radiation Therapy

for Throat Cancer

The researchers are doing this study to find out if a personalized approach to chemoradiation therapy (which may include a lower dose of radiation) is as effective as the standard chemoradiation therapy in people with HPV-positive throat cancer. Other purposes of this study include looking at the following: * Whether a lower dose of radiation in combination with standard chemotherapy causes fewer side effects than the standard dose of radiation therapy in combination with standard chemotherapy * How the study approaches (lower dose of radiation therapy + standard chemotherapy and standard dose of radiation therapy + standard chemotherapy) affect participants' quality of life. The researchers will measure quality of life by having participants fill out questionnaires.

Recruiting

2 awards

Phase 3

5 criteria

More about Nancy Lee, MD

Clinical Trial Related

2 years of experience running clinical trials · Led 14 trials as a Principal Investigator · 4 Active Clinical Trials

Treatments Nancy Lee, MD has experience with

  • Cisplatin
  • Intensity-Modulated Radiation Therapy
  • Carboplatin
  • Proton Therapy
  • Telemedicine Surveillance (tele-surveillance)
  • Questionnaires

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