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6 Crovalimab Trials Near You
Power is an online platform that helps thousands of patients discover FDA-reviewed trials every day. Every trial we feature meets safety and ethical standards, giving patients an easy way to discover promising new treatments in the research stage.
Learn More About PowerCrovalimab for Atypical Hemolytic Uremic Syndrome
Columbus, Ohio
This trial aims to test the effectiveness and safety of crovalimab in adults and adolescents with aHUS. Crovalimab helps by calming an overactive immune system that can harm blood vessels and kidneys.
No Placebo Group
Pivotal Trial (Near Approval)
Trial Details
Trial Status:Active Not Recruiting
Trial Phase:Phase 3
Age:12+
Sex:All
Key Eligibility Criteria
Disqualifiers:Non-aHUS Renal Disease, HIV, Others
Must Be Taking:C5 Inhibitors
83 Participants Needed
This trial is testing the safety of crovalimab and eculizumab in patients with PNH who are already on medications. Both drugs work by stopping the immune system from destroying red blood cells. Eculizumab, a medication that was first approved for PNH in 2007, has revolutionized the treatment of this disease.
No Placebo Group
Pivotal Trial (Near Approval)
Trial Details
Trial Status:Active Not Recruiting
Trial Phase:Phase 3
Age:2+
Sex:All
Key Eligibility Criteria
Disqualifiers:Bone Marrow Transplant, Myelodysplastic Syndrome, Hepatitis B/C, Others
Must Be Taking:Complement Inhibitors
190 Participants Needed
Crovalimab for Atypical Hemolytic Uremic Syndrome
Cincinnati, Ohio
This trial is testing crovalimab, a medication that helps control the immune system, in children with a rare disease called aHUS. The goal is to see if it is safe and effective for these patients. Crovalimab works by calming down an overactive part of the immune system to prevent damage to the body. Another similar medication, eculizumab, has been used effectively to treat aHUS by inhibiting the complement system.
No Placebo Group
Pivotal Trial (Near Approval)
Trial Details
Trial Status:Active Not Recruiting
Trial Phase:Phase 3
Age:28 - 17
Sex:All
Key Eligibility Criteria
Disqualifiers:HIV, Hepatitis B/C, Malignancy, Others
Must Be Taking:C5 Inhibitors
41 Participants Needed
Crovalimab for Sickle Cell Disease
Detroit, Michigan
This trial is testing crovalimab to see if it can safely and effectively prevent painful episodes in people with Sickle Cell Disease by stopping the immune system from causing blood vessel blockages.
Trial Details
Trial Status:Active Not Recruiting
Trial Phase:Phase 2
Age:12 - 55
Sex:All
Key Eligibility Criteria
Disqualifiers:Stem Cell Transplant, Chronic Transfusion, HIV, Others
90 Participants Needed
Crovalimab for Sickle Cell Disease
Detroit, Michigan
This trial is testing crovalimab, a medication, to see if it can help treat severe pain crises in people with sickle cell disease. The study focuses on adults and adolescents who need hospital care for their pain. Researchers will check how the body handles crovalimab and its effects to ensure it is safe and effective.
Trial Details
Trial Status:Active Not Recruiting
Trial Phase:Phase 1
Age:12 - 55
Sex:All
Key Eligibility Criteria
Disqualifiers:Frequent VOEs, Severe Infection, HIV, Others
30 Participants Needed
Crovalimab vs Eculizumab for Paroxysmal Nocturnal Hemoglobinuria
Charlotte, North Carolina
This trial is testing if crovalimab is as effective as eculizumab in treating people with PNH who haven't received similar treatments before. Both medications help prevent the immune system from attacking red blood cells. Eculizumab is a treatment for paroxysmal nocturnal hemoglobinuria (PNH) that decreases intravascular hemolysis and thrombosis and improves survival.
No Placebo Group
Pivotal Trial (Near Approval)
Trial Details
Trial Status:Active Not Recruiting
Trial Phase:Phase 3
Age:2+
Sex:All
Key Eligibility Criteria
Disqualifiers:Bone Marrow Transplant, Myelodysplastic Syndrome, Pregnancy, Hepatitis B/C, Others
Must Not Be Taking:Complement Inhibitors
204 Participants Needed
Learn More About Power
We started Power when my dad was diagnosed with multiple myeloma, and I struggled to help him access the latest immunotherapy. Hopefully Power makes it simpler for you to explore promising new treatments, during what is probably a difficult time.
Bask GillCEO at Power
Frequently Asked Questions
How much do clinical trials pay?
Each trial will compensate patients a different amount, but $50-100 for each visit is a fairly common range for Phase 2–4 trials (Phase 1 trials often pay substantially more). Further, most trials will cover the costs of a travel to-and-from the clinic.How do clinical trials work?
After a researcher reviews your profile, they may choose to invite you in to a screening appointment, where they'll determine if you meet 100% of the eligibility requirements. If you do, you'll be sorted into one of the treatment groups, and receive your study drug. For some trials, there is a chance you'll receive a placebo. Across trials 30% of clinical trials have a placebo. Typically, you'll be required to check-in with the clinic every month or so. The average trial length is 12 months.How do I participate in a study as a "healthy volunteer"?
Not all studies recruit healthy volunteers: usually, Phase 1 studies do. Participating as a healthy volunteer means you will go to a research facility several times over a few days or weeks to receive a dose of either the test treatment or a "placebo," which is a harmless substance that helps researchers compare results. You will have routine tests during these visits, and you'll be compensated for your time and travel, with the number of appointments and details varying by study.What does the "phase" of a clinical trial mean?
The phase of a trial reveals what stage the drug is in to get approval for a specific condition. Phase 1 trials are the trials to collect safety data in humans. Phase 2 trials are those where the drug has some data showing safety in humans, but where further human data is needed on drug effectiveness. Phase 3 trials are in the final step before approval. The drug already has data showing both safety and effectiveness. As a general rule, Phase 3 trials are more promising than Phase 2, and Phase 2 trials are more promising than phase 1.Do I need to be insured to participate in a medical study ?
Clinical trials are almost always free to participants, and so do not require insurance. The only exception here are trials focused on cancer, because only a small part of the typical treatment plan is actually experimental. For these cancer trials, participants typically need insurance to cover all the non-experimental components.What are the newest clinical trials ?
Most recently, we added Crovalimab for Sickle Cell Disease, Crovalimab for Sickle Cell Disease and Crovalimab for Atypical Hemolytic Uremic Syndrome to the Power online platform.Popular Searches
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