Testicular Cancer Clinical Trials 2023

What Are Testicular Cancer Clinical Trials?

Testicular cancer forms when malignant cells start forming in the testicles. These testicles, also known as testes, are covered by a loose bag of skin called the scrotum. Most cases of testicular cancer arise from germ cells in the testicles that clump together to form a mass or tumor.

There are two types of testicular cancer arising from germ cells: seminoma and non-seminoma. Both types of testicular cancer have subtypes that may require different treatment protocols. Non-seminoma testicular cancer primarily affects men in their late teens to early 30s.

Testicular cancer can affect men of any age group but is most commonly found between ages 15 to 44. It is relatively rare and can be treated if diagnosed early. The risk of death with testicular cancer is small as long as the early treatment is. More testicular cancer clinical trials can be used to discover more effective treatment methodologies and diagnostic tools.

Why Is Testicular Cancer Being Studied Through Clinical Trials?

Researchers are looking for more effective ways to care for testicular cancer patients. To discover new treatments, doctors conduct testicular cancer clinical trials that involve volunteers. These trials are used for all stages of testicular cancer. The main focus is finding new treatments for safer and alternative methods. These studies look for new drugs and approaches to radiation therapy.

What Are The Types of Treatments Available For Testicular Cancer?

A team of doctors works to find the most effective treatment plan for patients. The choice of treatment depends on the patient’s health and how far the disease has progressed. Treatment options include surgery, radiation, and chemotherapy.

Surgery is the primary course of action for treating testicular cancer. In some cases, the entire testis may be removed to treat testicular cancer. Patients are regularly monitored to ensure that the cancer does not return. Removal of one testis should not affect testosterone levels.

Surgery may be combined with radiation and chemotherapy to kill cancer cells. Most testicular tumors are highly susceptible to chemotherapy because the cells are close to apoptotic death. Drugs, including Cosmegen, Cisplatin, and Etoposide, are also prescribed for treating testicular cancer.

What Are Some Recent Breakthrough Clinical Trials For Testicular Cancer?

1998: Dose-intensified Chemotherapy - This study of over 218 patients with advanced testicular cancer studied the impact of high-dose chemotherapy on tumors. It concluded that, despite favorable results, the treatment should not be prescribed to patients because of adverse side effects. More controlled clinical trials over the long term should be evaluated to study the impact of dose-intensified chemotherapy.

2018: Effect of HIIT on Testicular Cancer Survivors - This clinical trial examined the effect of high-intensity interval training on the quality of life of patients who have survived testicular cancer. Researchers explored cardiovascular fitness in several patients over the course of 12 weeks to determine the effect of HIIT. It was found that HIIT significantly improved patients’ quality of life in the long run.