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We started Power when my dad was diagnosed with multiple myeloma, and I struggled to help him access the latest immunotherapy. Hopefully Power makes it simpler for you to explore promising new treatments, during what is probably a difficult time.

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Bask GillCEO at Power
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      Why We Started Power

      We started Power when my dad was diagnosed with multiple myeloma, and I struggled to help him access the latest immunotherapy. Hopefully Power makes it simpler for you to explore promising new treatments, during what is probably a difficult time.

      Bask
      Bask GillCEO at Power
      Learn More About Trials
      How Do Clinical Trials Work?Are Clinical Trials Safe?What Can I Expect During a Clinical Trial?

      4 Treatment Resistant Depression Trials near Colorado

      Power is an online platform that helps thousands of Treatment Resistant Depression patients discover FDA-reviewed trials every day. Every trial we feature meets safety and ethical standards, giving patients an easy way to discover promising new treatments in the research stage.

      Learn More About Power
      No Placebo
      Highly Paid
      Stay on Current Meds
      Pivotal Trials (Near Approval)
      Breakthrough Medication
      Active on Power

      Psychedelic-Assisted Therapy for Treatment Resistant Depression

      Denver, Colorado
      This study is testing VLS-01, a treatment containing DMT that is placed in the mouth and dissolved, to see if it can quickly help people with depression who haven’t improved with other treatments. Participants will receive either 1 or 3 doses of VLS-01, with support throughout the study, to evaluate its safety and effectiveness.

      Trial Details

      Trial Status:Recruiting
      Trial Phase:Phase 2
      Age:18 - 65

      Key Eligibility Criteria

      Disqualifiers:Psychotic Disorders, Substance Use, Cardiovascular, Others
      Must Be Taking:Antidepressants

      142 Participants Needed

      Psilocybin for Depression

      Aurora, Colorado
      The purpose of this study is to evaluate the efficacy of psilocybin on the symptom of anhedonia in individuals with treatment-resistant major depressive disorder.

      Trial Details

      Trial Status:Recruiting
      Trial Phase:Phase 2
      Age:21 - 75

      Key Eligibility Criteria

      Disqualifiers:Psychotic Disorders, Bipolar, SUDs, Others
      Must Not Be Taking:Antipsychotics, Tricyclics, MAOIs, Others

      40 Participants Needed

      BPL-003 for Treatment Resistant Depression

      Fort Collins, Colorado
      This trial tests a nasal spray drug called BPL-003 along with counseling for people whose depression doesn't get better with usual treatments. The drug aims to quickly improve mood, and counseling helps provide emotional support.
      No Placebo Group

      Trial Details

      Trial Status:Active Not Recruiting
      Trial Phase:Phase 2

      Key Eligibility Criteria

      Disqualifiers:Schizophrenia, Bipolar, Substance Use, Others
      Must Not Be Taking:Antidepressants

      196 Participants Needed

      Cognitive Behavioral Therapy for Depression and Insulin Sensitivity in Adolescents

      Aurora, Colorado
      There has been a rise in type 2 diabetes (T2D) rates in adolescents, disproportionately in girls from disadvantaged racial/ethnic groups. This group of girls also is at heightened risk for depression, and depression and T2D are linked. Depressive symptoms are a risk factor for worsening of insulin sensitivity, one if the major precursors to T2D. In preliminary studies, the investigators found that a brief cognitive-behavioral therapy group decreased depressive symptoms and prevented worsening of insulin sensitivity in adolescent girls at-risk for T2D with moderate depressive symptoms. The aims of this study are: 1) to assess the efficacy of a cognitive-behavioral therapy depression group vs. a health education control group for improving insulin sensitivity and preserving insulin secretion in racially/ethnically diverse adolescent girls at-risk for T2D with moderate depressive symptoms over a 1-year follow-up; 2) to evaluate changes in eating, physical activity, and sleep as explanatory and 3) to test changes in cortisol factors as explanatory.
      No Placebo Group

      Trial Details

      Trial Status:Active Not Recruiting
      Trial Phase:Unphased
      Age:12 - 17
      Sex:Female

      Key Eligibility Criteria

      Disqualifiers:Pregnancy, Type 2 Diabetes, Major Psychiatric Disorders, Others
      Must Not Be Taking:Insulin Sensitizers, Antidepressants, Stimulants

      147 Participants Needed

      Why Other Patients Applied

      "I've heard great things about ketamine for treatment resistant depression and PTSD but haven't been able to try it. I've been struggling to find something to alleviate my symptoms since my son passed away in 2017."

      XB
      Treatment-Resistant Depression PatientAge: 54

      "I've tried 8 or 9 different combinations of antidepressants (SSRI, SNRI, etc) + antipsychotics, mood stabilizers, anxiolytics... I’ve been through on- and off-label treatments, I've had at least 4 serious side effcts in the 10 years I've been on antidepressants. I've done PGx testing for genetic markers, too. My experience finding appropriate treatment has been lonely, exhausting. I'd love to participate in something that helps others like me."

      HZ
      Treatment-Resistant Depression PatientAge: 31

      "I tried Prozac, Lamictal, TMS, a psychotherapy, and mindfulness meditation. These treatments provided limited relief. I hope for a new treatment that will be more effective. Looking for something that lasts long-term so that I can get my life back."

      HY
      Depression PatientAge: 63

      "I'm taking a medication for anxiety and it's not helping/working. I want to try and find something that would help with my anxiety. My research brought me to clinical trials."

      ZD
      Anxiety PatientAge: 36

      "I’ve tried so many drugs and treatments for depression it won’t go away or if it does it just comes back. I want to help others who may have this awful condition while also helping myself. If something new works for me, maybe it'll work for other people too."

      WK
      Depression PatientAge: 56
      Match to a Treatment Resistant Depression Trial

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      Why We Started Power

      We started Power when my dad was diagnosed with multiple myeloma, and I struggled to help him access the latest immunotherapy. Hopefully Power makes it simpler for you to explore promising new treatments, during what is probably a difficult time.

      Bask
      Bask GillCEO at Power
      Learn More About Trials
      How Do Clinical Trials Work?Are Clinical Trials Safe?What Can I Expect During a Clinical Trial?
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      Frequently Asked Questions

      How much do Treatment Resistant Depression clinical trials in Colorado pay?

      Each trial will compensate patients a different amount, but $50-100 for each visit is a fairly common range for Phase 2–4 trials (Phase 1 trials often pay substantially more). Further, most trials will cover the costs of a travel to-and-from the clinic.

      How do Treatment Resistant Depression clinical trials in Colorado work?

      After a researcher reviews your profile, they may choose to invite you in to a screening appointment, where they'll determine if you meet 100% of the eligibility requirements. If you do, you'll be sorted into one of the treatment groups, and receive your study drug. For some trials, there is a chance you'll receive a placebo. Across Treatment Resistant Depression trials in Colorado 30% of clinical trials have a placebo. Typically, you'll be required to check-in with the clinic every month or so. The average trial length in Colorado for Treatment Resistant Depression is 12 months.

      How do I participate in a study as a "healthy volunteer"?

      Not all studies recruit healthy volunteers: usually, Phase 1 studies do. Participating as a healthy volunteer means you will go to a research facility in Colorado several times over a few days or weeks to receive a dose of either the test treatment or a "placebo," which is a harmless substance that helps researchers compare results. You will have routine tests during these visits, and you'll be compensated for your time and travel, with the number of appointments and details varying by study.

      What does the "phase" of a clinical trial mean?

      The phase of a trial reveals what stage the drug is in to get approval for a specific condition. Phase 1 trials are the trials to collect safety data in humans. Phase 2 trials are those where the drug has some data showing safety in humans, but where further human data is needed on drug effectiveness. Phase 3 trials are in the final step before approval. The drug already has data showing both safety and effectiveness. As a general rule, Phase 3 trials are more promising than Phase 2, and Phase 2 trials are more promising than phase 1.

      Do I need to be insured to participate in a Treatment Resistant Depression medical study in Colorado?

      Clinical trials are almost always free to participants, and so do not require insurance. The only exception here are trials focused on cancer, because only a small part of the typical treatment plan is actually experimental. For these cancer trials, participants typically need insurance to cover all the non-experimental components.

      What are the newest Treatment Resistant Depression clinical trials in Colorado?

      Most recently, we added VLS-01 Buccal Film for Depression, Psilocybin for Depression and BPL-003 for Treatment Resistant Depression to the Power online platform.