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Trial Phase
Trial Status
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90 Parkinson Trials Near You
Power is an online platform that helps thousands of Parkinson patients discover FDA-reviewed trials every day. Every trial we feature meets safety and ethical standards, giving patients an easy way to discover promising new treatments in the research stage.
Learn More About PowerVirtual Rehab Cycling for Parkinson's Disease
Trial Details
Key Eligibility Criteria
72 Participants Needed
Adaptive DBS for Parkinson's Disease
Trial Details
Key Eligibility Criteria
85 Participants Needed
Genetic Testing for Parkinson's Disease
Trial Details
Key Eligibility Criteria
1982 Participants Needed
Long-Term Treatment for Parkinson's Disease
Trial Details
Key Eligibility Criteria
220 Participants Needed
Deep Brain Stimulation Adjustments for Parkinson's Disease
Trial Details
Key Eligibility Criteria
15 Participants Needed
Alternating-Frequency DBS for Parkinson's Disease
Trial Details
Key Eligibility Criteria
12 Participants Needed
Lifestyle Interventions for Neurological Disorders
Trial Details
Key Eligibility Criteria
200 Participants Needed
DSP-1083 for Parkinson's Disease
Trial Details
Key Eligibility Criteria
23 Participants Needed
Peripheral Nerve Tissue Implantation for Parkinson's Disease
Trial Details
Key Eligibility Criteria
24 Participants Needed
Nerve Tissue Implantation for Parkinson's Disease
Trial Details
Key Eligibility Criteria
10 Participants Needed
Nerve Grafts + DBS Surgery for Parkinson's Disease
Trial Details
Key Eligibility Criteria
70 Participants Needed
Sural Nerve Graft for Parkinson's Disease
Trial Details
Key Eligibility Criteria
7 Participants Needed
ABBV-951 for Parkinson's Disease
Trial Details
Key Eligibility Criteria
130 Participants Needed
Varenicline for Parkinson's Disease
Trial Details
Key Eligibility Criteria
102 Participants Needed
Carbidopa + Levodopa for Parkinsonism
Trial Details
Key Eligibility Criteria
6 Participants Needed
Citalopram for Parkinson's Disease
Trial Details
Key Eligibility Criteria
58 Participants Needed
TB006 for Parkinson's Disease
Trial Details
Key Eligibility Criteria
62 Participants Needed
Gene Therapy for Parkinson's Disease
Trial Details
14 Participants Needed
rTMS for Impulse Control Disorders in Parkinson's Disease
Trial Details
Key Eligibility Criteria
20 Participants Needed
Vibro-Acoustic Therapy for Parkinson's Disease
Trial Details
Key Eligibility Criteria
1 Participants Needed
Why Other Patients Applied
"I changed my diet in 2020 and I’ve lost 95 pounds from my highest weight (283). I am 5’3”, female, and now 188. I still have a 33 BMI. I've been doing research on alternative approaches to continue my progress, which brought me here to consider clinical trials."
"I have dealt with voice and vocal fold issues related to paralysis for over 12 years. This problem has negatively impacted virtually every facet of my life. I am an otherwise healthy 48 year old married father of 3 living. My youngest daughter is 12 and has never heard my real voice. I am now having breathing issues related to the paralysis as well as trouble swallowing some liquids. In my research I have seen some recent trials focused on helping people like me."
"I've tried several different SSRIs over the past 23 years with no luck. Some of these new treatments seem interesting... haven't tried anything like them before. I really hope that one could work."
"My orthopedist recommended a half replacement of my right knee. I have had both hips replaced. Currently have arthritis in knee, shoulder, and thumb. I want to avoid surgery, and I'm open-minded about trying a trial before using surgery as a last resort."
"I've been struggling with ADHD and anxiety since I was 9 years old. I'm currently 30. I really don't like how numb the medications make me feel. And especially now, that I've lost my grandma and my aunt 8 days apart, my anxiety has been even worse. So I'm trying to find something new."
Accelerated Brain Stimulation for Parkinson's Disease
Trial Details
Key Eligibility Criteria
20 Participants Needed
Inner Ear Stimulation for Parkinson's Disease
Trial Details
Key Eligibility Criteria
64 Participants Needed
Burst-Type Deep Brain Stimulation for Parkinson's Disease
Trial Details
Key Eligibility Criteria
5 Participants Needed
CranioSacral Therapy for Parkinson's Disease
Trial Details
Key Eligibility Criteria
5 Participants Needed
Exercise + Ketone Supplement for Parkinson's Disease
Trial Details
Key Eligibility Criteria
24 Participants Needed
Gene Transfer for Pompe Disease
Trial Details
Key Eligibility Criteria
4 Participants Needed
Robotic Gait Training for Parkinson's Disease
Trial Details
Key Eligibility Criteria
30 Participants Needed
Stem Cell Injections for Amputation Complications
Trial Details
Key Eligibility Criteria
81 Participants Needed
Bemdaneprocel for Parkinson's Disease
Trial Details
Key Eligibility Criteria
102 Participants Needed
BHV-8000 for Parkinson's Disease
Trial Details
Key Eligibility Criteria
550 Participants Needed
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Frequently Asked Questions
How much do Parkinson clinical trials pay?
Each trial will compensate patients a different amount, but $50-100 for each visit is a fairly common range for Phase 2–4 trials (Phase 1 trials often pay substantially more). Further, most trials will cover the costs of a travel to-and-from the clinic.
How do Parkinson clinical trials work?
After a researcher reviews your profile, they may choose to invite you in to a screening appointment, where they'll determine if you meet 100% of the eligibility requirements. If you do, you'll be sorted into one of the treatment groups, and receive your study drug. For some trials, there is a chance you'll receive a placebo. Across Parkinson trials 30% of clinical trials have a placebo. Typically, you'll be required to check-in with the clinic every month or so. The average trial length for Parkinson is 12 months.
How do I participate in a study as a "healthy volunteer"?
Not all studies recruit healthy volunteers: usually, Phase 1 studies do. Participating as a healthy volunteer means you will go to a research facility several times over a few days or weeks to receive a dose of either the test treatment or a "placebo," which is a harmless substance that helps researchers compare results. You will have routine tests during these visits, and you'll be compensated for your time and travel, with the number of appointments and details varying by study.
What does the "phase" of a clinical trial mean?
The phase of a trial reveals what stage the drug is in to get approval for a specific condition. Phase 1 trials are the trials to collect safety data in humans. Phase 2 trials are those where the drug has some data showing safety in humans, but where further human data is needed on drug effectiveness. Phase 3 trials are in the final step before approval. The drug already has data showing both safety and effectiveness. As a general rule, Phase 3 trials are more promising than Phase 2, and Phase 2 trials are more promising than phase 1.
Do I need to be insured to participate in a Parkinson medical study?
Clinical trials are almost always free to participants, and so do not require insurance. The only exception here are trials focused on cancer, because only a small part of the typical treatment plan is actually experimental. For these cancer trials, participants typically need insurance to cover all the non-experimental components.
What are the newest Parkinson clinical trials?
Most recently, we added Accelerated Brain Stimulation for Parkinson's Disease, Exercise Program for Parkinson's Disease and Peripheral Nerve Tissue Implantation for Parkinson's Disease to the Power online platform.
What is the best treatment for Parkinson's disease available currently?
There is no single “best” treatment for Parkinson’s; doctors tailor a plan that usually starts with carbidopa/levodopa (the most effective pill for stiffness and slowness) and may add other drugs, regular exercise/physical therapy, and lifestyle measures. When pills no longer give steady relief, advanced options such as deep-brain stimulation or continuous medication pumps can dramatically smooth movement. Because the right mix depends on your age, symptoms, and other health issues, seeing a movement-disorder specialist is the quickest way to find the combination that’s best for you.
What are two new early signs of Parkinson's?
Two early warning clues doctors now watch for are: (1) a fading or lost sense of smell—foods taste bland and familiar odors like coffee or perfume are hard to detect—and (2) “acting out” dreams during sleep (REM-sleep behaviour disorder) where a person kicks, punches, or shouts while dreaming instead of lying still. These changes can appear 5–10 years before the typical shaking or slowness of Parkinson’s; if either symptom shows up without a clear cause, mention it to your doctor because many other issues (allergies, medications, sleep apnea, etc.) can also trigger them.
What not to eat with Parkinson's?
To keep your medicines working their best, take levodopa on an empty stomach or at least 30–60 min before meals and save most of the day’s protein (meat, eggs, beans, protein shakes) for evening; large protein, iron, or calcium doses given with the pill can block its absorption. If you use an MAO-B inhibitor such as rasagiline or selegiline, limit aged cheeses, cured meats, soy sauce, or other “tyramine-rich” foods because they can spike blood pressure. Beyond these drug-specific issues, a diet built around vegetables, fruit, whole grains, and fish—while going easy on ultra-processed snacks, excess red meat, and large amounts of dairy—has been linked to slower symptom progression, so tailor changes with your doctor or a dietitian.
What is the root cause of Parkinson's disease?
Scientists have not found one “root” trigger; Parkinson’s usually arises when several things converge. Inherited gene changes (such as in SNCA or LRRK2), long-term exposure to toxins like certain pesticides/solvents, and the natural aging of brain cells can each promote misfolded α-synuclein, malfunctioning mitochondria, and oxidative stress—processes that gradually destroy the dopamine-making neurons. In short, dopamine loss is the final outcome of a complex mix of genetic, environmental, and age-related factors rather than the starting cause.
What is the 5:2:1 rule for Parkinson's?
Doctors use the “5-2-1” rule as a fast way to spot people whose Parkinson’s may no longer be well-controlled by standard tablets: if you need levodopa five or more times a day, still spend two or more waking hours in an “OFF” state (when the medicine has worn off and stiffness, slowness or tremor return), and experience at least one hour of bothersome involuntary movements (“dyskinesia”) daily. Meeting all three points flags “advanced” Parkinson’s and should prompt a conversation with a movement-disorder specialist about options such as adjusting medication, infusion pumps, or deep-brain stimulation.
How long does it take to go from stage 1 to stage 4 Parkinson's?
In large long-term studies, people who do reach Hoehn & Yahr stage 4 usually take about 8–15 years to get there from stage 1, but extremes of only a few years or more than two decades are documented, and roughly one-third never progress that far at all. How quickly someone moves through the stages depends on things like age at diagnosis, the type of symptoms they start with, their response to medication or deep-brain stimulation, and lifestyle factors such as regular exercise.
How do you make someone with Parkinson's happy?
Ask the person what still brings them joy and what is hardest right now, then focus on two things science shows lift quality of life in Parkinson’s: removing distress (on-time medication, treating depression or poor sleep, making the home and tasks easier so they stay independent) and adding pleasure (regular exercise or dance, music, hobbies, and time with friends or support groups). By pairing practical help with activities that move the body and keep social ties strong, you create the conditions where feeling happier is much more likely.
What happens if you take carbidopa levodopa and you don't have Parkinson's?
Carbidopa-levodopa is meant to replace missing dopamine in Parkinson’s disease; in someone without that deficiency it provides no upside and may cause typical drug reactions such as nausea, dizziness from low blood pressure, palpitations, restless or jerky movements, and mood or sleep disturbances. Because these effects can appear after even a few doses and the medicine could complicate the evaluation of other neurologic problems, it should only be taken under a doctor’s direction—not as a trial on your own.
What is the finger test for Parkinson's?
Doctors ask the patient to rapidly tap the tip of the index finger against the thumb for about 10 seconds on each hand; they look not just at speed but at whether the taps quickly get smaller, slower, or irregular. A normal tap remains quick and wide; taps that lose size or rhythm, hesitate, or differ from one side to the other signal the bradykinesia that helps diagnose and monitor Parkinson’s disease.