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Trial Phase
Trial Status
Paid Participation
64 Menopause Trials Near You
Power is an online platform that helps thousands of Menopause patients discover FDA-reviewed trials every day. Every trial we feature meets safety and ethical standards, giving patients an easy way to discover promising new treatments in the research stage.
Learn More About PowerPre-op Radiation + Abemaciclib + Letrozole for Breast Cancer
Trial Details
Key Eligibility Criteria
15 Participants Needed
Exercise Therapy for Breast Cancer
Trial Details
Key Eligibility Criteria
152 Participants Needed
Mobile App for Hot Flashes
Trial Details
Key Eligibility Criteria
90 Participants Needed
Tocotrienols for Obesity
Trial Details
Key Eligibility Criteria
60 Participants Needed
Why Other Patients Applied
"I was diagnosed with stage 4 pancreatic cancer three months ago, metastatic to my liver, and I have been receiving and responding well to chemotherapy. My blood work revealed that my tumor markers have gone from 2600 in the beginning to 173 as of now, even with the delay in treatment, they are not going up. CT Scans reveal they have been shrinking as well. However, chemo is seriously deteriorating my body. I have 4 more treatments to go in this 12 treatment cycle. I am just interested in learning about my other options, if any are available to me."
"I changed my diet in 2020 and I’ve lost 95 pounds from my highest weight (283). I am 5’3”, female, and now 188. I still have a 33 BMI. I've been doing research on alternative approaches to continue my progress, which brought me here to consider clinical trials."
"I've tried several different SSRIs over the past 23 years with no luck. Some of these new treatments seem interesting... haven't tried anything like them before. I really hope that one could work."
"My orthopedist recommended a half replacement of my right knee. I have had both hips replaced. Currently have arthritis in knee, shoulder, and thumb. I want to avoid surgery, and I'm open-minded about trying a trial before using surgery as a last resort."
"I've been struggling with ADHD and anxiety since I was 9 years old. I'm currently 30. I really don't like how numb the medications make me feel. And especially now, that I've lost my grandma and my aunt 8 days apart, my anxiety has been even worse. So I'm trying to find something new."
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We started Power when my dad was diagnosed with multiple myeloma, and I struggled to help him access the latest immunotherapy. Hopefully Power makes it simpler for you to explore promising new treatments, during what is probably a difficult time.
Frequently Asked Questions
How much do Menopause clinical trials pay?
Each trial will compensate patients a different amount, but $50-100 for each visit is a fairly common range for Phase 2–4 trials (Phase 1 trials often pay substantially more). Further, most trials will cover the costs of a travel to-and-from the clinic.
How do Menopause clinical trials work?
After a researcher reviews your profile, they may choose to invite you in to a screening appointment, where they'll determine if you meet 100% of the eligibility requirements. If you do, you'll be sorted into one of the treatment groups, and receive your study drug. For some trials, there is a chance you'll receive a placebo. Across Menopause trials 30% of clinical trials have a placebo. Typically, you'll be required to check-in with the clinic every month or so. The average trial length for Menopause is 12 months.
How do I participate in a study as a "healthy volunteer"?
Not all studies recruit healthy volunteers: usually, Phase 1 studies do. Participating as a healthy volunteer means you will go to a research facility several times over a few days or weeks to receive a dose of either the test treatment or a "placebo," which is a harmless substance that helps researchers compare results. You will have routine tests during these visits, and you'll be compensated for your time and travel, with the number of appointments and details varying by study.
What does the "phase" of a clinical trial mean?
The phase of a trial reveals what stage the drug is in to get approval for a specific condition. Phase 1 trials are the trials to collect safety data in humans. Phase 2 trials are those where the drug has some data showing safety in humans, but where further human data is needed on drug effectiveness. Phase 3 trials are in the final step before approval. The drug already has data showing both safety and effectiveness. As a general rule, Phase 3 trials are more promising than Phase 2, and Phase 2 trials are more promising than phase 1.
Do I need to be insured to participate in a Menopause medical study?
Clinical trials are almost always free to participants, and so do not require insurance. The only exception here are trials focused on cancer, because only a small part of the typical treatment plan is actually experimental. For these cancer trials, participants typically need insurance to cover all the non-experimental components.
What are the newest Menopause clinical trials?
Most recently, we added Cognitive Behavioral Therapy for Menopause, Hot Water Therapy for Menopause-Related Hot Flashes and PROSOMNIA Sleep Therapy for Chronic Insomnia to the Power online platform.
How to reverse menopause naturally?
Natural menopause—the point when ovaries have run out of viable eggs—is biologically irreversible, so no diet, herb, or supplement can make regular periods and fertility reliably return. What you can do is (a) avoid reaching menopause a bit earlier than necessary by not smoking, maintaining a healthy weight, and eating a mostly plant-based, fish-and-legume-rich diet, and (b) lessen hot flashes, sleep trouble, and mood changes with regular exercise, stress-reduction, and cautiously tested aids such as soy foods or short-term black cohosh—checking with your healthcare provider first for interactions or liver concerns. If symptoms are still disruptive, discuss stronger evidence-based options like hormone therapy or newer non-hormonal medications with a clinician.
What stage of menopause is the hardest?
For most women, the toughest stretch is late perimenopause and the first year or two after the final period, when estrogen and progesterone swing unpredictably and then fall, driving hot flashes, sleep loss, and mood changes. Individual experience varies—sudden surgical menopause, smoking, stress, or other health issues can shift when symptoms feel worst—so the “hardest stage” is personal. Track your own pattern and discuss lifestyle tweaks or hormone/non-hormone treatments with a menopause-savvy clinician to ease whatever phase is giving you the most trouble.
Is 46 too early for menopause?
Menopause at 46 is at the younger end of the normal 45-55-year range, so it isn’t considered “too early” (only menopause before 45 is classed as early and before 40 as premature). Let your clinician know so they can rule out other causes, discuss symptom relief, and check bone and heart health, but in most cases menopause at 46 is simply a normal variation.
Which hormone replacement therapy is best for weight loss?
Hormone replacement is only helpful for weight when it corrects a proven deficiency: estrogen/progestin can trim about 1 kg of the usual mid-life gain, levothyroxine stops further gain in true hypothyroidism, and testosterone adds lean tissue but little fat loss in women who are genuinely low. If your hormone levels are normal, none of these therapies will make you slimmer, so treatment choice should focus on relieving deficiency-related symptoms while weight control relies on diet, activity, and (when appropriate) dedicated anti-obesity drugs like semaglutide, which is not HRT.
What are the signs that you need hormone replacement therapy?
Think of hormone replacement as a tool for clearly defined situations, not a catch-all fix. For women, doctors consider systemic estrogen (with or without progestin) when hot flashes, night sweats, or vaginal dryness are moderate-to-severe or when menopause occurs early (<40 yrs) and is putting bones at risk; benefit is greatest if therapy starts within 10 years of the last period and there are no major heart-, clot-, or cancer-related contraindications. For men, testosterone is only offered when typical symptoms such as low libido, erectile problems, or loss of muscle strength coexist with TWO separate morning blood tests showing testosterone below the normal range—other causes must first be ruled out. If these criteria fit you, ask your clinician to review the pros, cons, and any needed screening (breast/prostate, heart, clot risk) before deciding on treatment.
Do you age faster without estrogen?
Time itself doesn’t speed up, but when estrogen drops after menopause the skin, bones and blood vessels start to thin, weaken and stiffen more quickly, so many women “show” aging sooner than before. Hormone therapy (or other bone- and skin-protective measures like exercise, good diet and sun protection) can slow some of these changes, but because estrogen can also raise the risk of blood clots, stroke or certain cancers, the decision to take it should be made with a doctor after weighing personal risks and goals.
What happens to a woman's body after menopause?
Once your periods have been gone for 12 months, estrogen from the ovaries drops to very low levels; in the near term this can cause hot flashes, poor sleep and vaginal dryness, while over the years it speeds up bone loss, shifts cholesterol and belly fat in ways that raise heart-disease risk, and thins skin, hair and pelvic-floor tissues. The good news is that most symptoms can be eased (for example with targeted hormone or non-hormone therapies) and the major risks can be curbed by weight-bearing exercise, calcium/vitamin D, not smoking, heart-healthy eating, and regular check-ups that include bone-density and cholesterol tests—so think in two buckets: manage bothersome symptoms now and adopt long-term habits and screenings to protect bones, heart and pelvic health.
What burns menopausal belly fat?
You can’t “spot-burn” belly fat, but studies show menopausal women shrink it fastest when they pair a slightly calorie-reduced, Mediterranean- or high-protein style diet with both progressive strength training (2-3 times a week) and moderate-to-vigorous or interval cardio (about 150 minutes weekly). Quality sleep, stress control and—if appropriate—discussing hormone therapy with your doctor help curb the hormonal shifts that push fat toward the waistline. Think of it as a three-legged stool: smart food choices, muscle-building plus heart-pumping movement, and restorative habits working together to whittle the mid-section.
What is the monthly injection for menopause?
The “monthly shot” is a long-acting estrogen called estradiol valerate or estradiol cypionate, sold as Delestrogen or Depo-Estradiol and typically injected into a muscle every 3–4 weeks to ease hot flashes and vaginal dryness. It is reserved for women who cannot use or do not absorb pills, patches, or gels; if you still have a uterus you must also take a progestin to protect the lining, and the usual estrogen safety cautions (blood-clot, stroke, breast-cancer risk) still apply, so the decision should be made with your clinician.
Why is HRT no longer recommended?
HRT wasn’t “banned”—practice simply shifted after large studies showed that, in women starting therapy well past menopause, the small benefits were outweighed by higher rates of breast cancer, blood clots, stroke and heart disease. Today, experts still recommend HRT as the most effective treatment for troublesome hot flushes and bone loss when started before age 60 or within 10 years of menopause, but they weigh each woman’s personal risks and stop or adjust it if those risks rise.