Bipolar Disorder Clinical Trials
Here are the 6 most popular medical studies for bipolar disorder
Behavioral Intervention
ITAP + SAFE for Bipolar and Substance Use Disorders
This trial is testing a new way to help people with bipolar disorder and addiction. Half the group will get a new program to help them, while the other half will just get closer monitoring.
Popular filter options for bipolar disorder trials
BD Clinical Trials
View 81 BD medical studies.
Behavioral Intervention
Contingency Management for Alcoholism in Severe Mental Illness
This trial will study whether two different approaches to contingency management (CM) can help reduce heavy drinking among people with serious mental illness and alcohol dependence who are seen at community mental health centers.
Behavioural Intervention
High-Touch, High-Tech Care for Chronic Conditions
This trial will enroll 1,927 adults with multiple chronic conditions who are at risk for repeated hospitalizations. The investigators will assess the impact of three payer-led options (e.g. High-Touch, High-Tech, Usual Care) on patient-centered outcomes, namely patient activation in health care, health status, and subsequent re-hospitalization.
Major Depressive Disorder Clinical Trials
View 32 Major Depressive Disorder medical studies.
Behavioral Intervention
Contingency Management for Alcoholism in Severe Mental Illness
This trial will study whether two different approaches to contingency management (CM) can help reduce heavy drinking among people with serious mental illness and alcohol dependence who are seen at community mental health centers.
Behavioural Intervention
High-Touch, High-Tech Care for Chronic Conditions
This trial will enroll 1,927 adults with multiple chronic conditions who are at risk for repeated hospitalizations. The investigators will assess the impact of three payer-led options (e.g. High-Touch, High-Tech, Usual Care) on patient-centered outcomes, namely patient activation in health care, health status, and subsequent re-hospitalization.
Phase 3 Bipolar Disorder Clinical Trials
View 97 phase 3 bipolar disorder medical studies.
Lurasidone for Cognitive Improvement in Bipolar Disorder
This trial is testing whether lurasidone can improve cognition in people with bipolar disorder who are in remission from an episode. Participants who show cognitive impairment at the screening visit will be enrolled and randomized to receive either lurasidone or placebo for 6 weeks.
Atypical Antipsychotic
Lumateperone for Bipolar Disorder
This trial is being conducted at multiple locations worldwide and will last for 26 weeks. It aims to evaluate the safety and tolerability of lumateperone in children with schizophrenia or bipolar disorder.
NMDA Antagonist
NRX100 +1 More for Depression, Bipolar Disorder
This trial will test whether NRX-100, a drug that reduces symptoms of depression and suicidal ideation, is better than placebo in treating patients with severe bipolar depression and acute suicidal ideation or behavior.
Bipolar Disorder Clinical Trials With No Placebo
View 97 bipolar disorder medical studies that do not have a placebo group.
Behavioral Intervention
Contingency Management for Alcoholism in Severe Mental Illness
This trial will study whether two different approaches to contingency management (CM) can help reduce heavy drinking among people with serious mental illness and alcohol dependence who are seen at community mental health centers.
Behavioural Intervention
High-Touch, High-Tech Care for Chronic Conditions
This trial will enroll 1,927 adults with multiple chronic conditions who are at risk for repeated hospitalizations. The investigators will assess the impact of three payer-led options (e.g. High-Touch, High-Tech, Usual Care) on patient-centered outcomes, namely patient activation in health care, health status, and subsequent re-hospitalization.
Behavioral Intervention
Mindfulness and CBT for Preventing Severe Mental Illness in Youth
This trial will test a new intervention to prevent severe mental illness in young people who are at high risk. The intervention will target early preceding factors to severe mental illness, which are often impairing and distressing to the individual but can be improved with self-management skills and parent training. The goal is to intervene early enough in the young person's life that severe mental illness can be prevented.
View More Bipolar Disorder Trials
See another 77 medical studies focused on bipolar disorder.
Frequently Asked Questions
Introduction to bipolar disorder
What are the top hospitals conducting bipolar disorder research?
Bipolar disorder, a complex mental health condition characterized by alternating periods of extreme highs and lows, is the focus of groundbreaking clinical trials conducted by top hospitals around the world. In Toronto, the Centre for Addiction and Mental Health leads the way with five active bipolar disorder trials and an impressive track record of eight completed studies since their first recorded trial in 2002. Meanwhile, in Houston, Texas, The University of Texas Health Science Center takes on this challenging condition with four ongoing trials and has made significant progress since embarking on research in 2015. Not far behind is the University of Texas at Austin, also contributing to our understanding of bipolar disorder through their current four clinical trials while pioneering investigations into this illness only began recently in 2019.
Moving across states to Ann Arbor, Michigan, researchers at the esteemed University of Michigan are actively engaged in three bipolar disorder trials as they build upon fifteen previous studies that have shaped our knowledge since initiating their first investigation back in 2009. Finally yet importantly,Toronto Western Hospital joins forces with its counterparts at home boasting three active clinical trials dedicated to better understanding bipolar disorder; these efforts started alongside those initiated by CAMH all those years ago back in2002.
These leading institutions exemplify a commitment to advancing our comprehension and treatment options for individuals living with bipolar disorder - helping countless patients find stability and improve their quality of life. By conducting cutting-edge research and collaborating across borders, these hospitals provide hope not just for those directly affected by this condition but also for future generations seeking effective interventions.
Which are the best cities for bipolar disorder clinical trials?
Toronto, Ontario, Austin (Texas), and Houston (Texas) emerge as the top cities for bipolar disorder clinical trials. Toronto leads with 13 ongoing studies focusing on treatments like Cannabidiol, Ketamine Hydrochloride, and other therapeutic approaches. Following closely behind are Austin and Houston with 10 and 8 active trials respectively investigating interventions such as NRX-101, Alcohol treatment options, and more. These cities offer individuals dealing with bipolar disorder access to cutting-edge research opportunities that may contribute to improved management of this condition.
Which are the top treatments for bipolar disorder being explored in clinical trials?
Promising breakthroughs in bipolar disorder treatment are emerging from ongoing clinical trials. Ketamine, a powerful drug initially listed in 2013, is currently being explored in three active trials for bipolar disorder. With its potential to alleviate symptoms and enhance mood stability, ketamine holds great promise as a novel therapeutic approach. Another exciting avenue of research is continuous Theta Burst Stimulation (cTBS), which made its first appearance on the scene in 2021. Already involved in two active trials focusing on bipolar disorder, cTBS shows potential as a non-invasive treatment option that could revolutionize how we manage this complex condition. As these studies progress, we move closer to finding more effective treatments for individuals living with bipolar disorder.
What are the most recent clinical trials for bipolar disorder?
Exciting strides are being made in the field of bipolar disorder research, with recent clinical trials offering new possibilities for treatment. One promising trial involves a combination of ketamine and perampanel, demonstrating potential benefits for individuals with bipolar disorder. Another study explores the effectiveness of inositol as a therapeutic option across different phases of the disorder. Additionally, ketamine is being evaluated in a Phase 3 trial to further understand its impact on bipolar disorder symptoms. Furthermore, an active treatment involving dexmedetomidine shows promise as it progresses through Phase 4 testing. Lastly, cariprazine holds potential as an intervention for individuals with bipolar disorder based on positive results observed during Phase 4 studies. These advancements offer hope and may pave the way towards improved management and quality of life for those living with this condition.
What bipolar disorder clinical trials were recently completed?
Recent clinical trials focusing on bipolar disorder have yielded significant findings, paving the way for improved treatments. In May 2022, the Medical University of South carolina successfully completed a trial investigating the potential benefits of N-Acetyl cysteine. Additionally, in August 2019, the University of California, San Diego concluded a trial examining Varenicline's efficacy in managing bipolar disorder symptoms. Furthermore, Yale University wrapped up their Ketamine study in November 2018. These pioneering studies underline ongoing efforts to enhance our understanding and treatment options for individuals with bipolar disorder.