UH Seidman Cancer Center at Southwest General Hospital

Summary

UH Seidman Cancer Center at Southwest General Hospital is a medical facility located in Cleveland, Ohio. This center is recognized for care of Lung Cancer, Breast Cancer, Breast cancer, Non-Small Cell Lung Cancer, Prostate Cancer and other specialties. UH Seidman Cancer Center at Southwest General Hospital is involved with conducting 101 clinical trials across 158 conditions. There are 28 research doctors associated with this hospital, such as Amy Armstrong, MD, Afshin Dowlati, MD, Lauren Henke, MD, and Richard T. Lee.

Top PIs

Clinical Trials running at UH Seidman Cancer Center at Southwest General Hospital

Breast Cancer

Lung Cancer

Esophageal Carcinoma

Ovarian Cancer

Breast cancer

Small Cell Lung Cancer

Gastroesophageal Junction Adenocarcinoma

Esophageal cancer

Oropharyngeal Carcinoma

Cancer

Omitting Radiation Therapy

for Breast Cancer

The purpose of this study is to compare the effects on low risk breast cancer receiving usual care that includes regional radiation therapy, with receiving no regional radiation therapy. Researchers want to see if not giving this type of radiation treatment works as well at preventing breast cancer from coming back.

Recruiting

2 awards

Phase 3

19 criteria

Carvedilol

for Preventing Heart Problems in HER2 Positive Breast Cancer

This trial has two cohorts of patients with human epidermal growth factor receptor (HER)-2-positive breast cancer that has spread to other places in the body. All patients must be receiving trastuzumab-based treatment. Both cohorts are being observed for cardiac toxicity. The largest cohort (currently open to accrual) is observational, and contains patients who are taking a beta blocker, ACE inhibitor, or ARB as well as their trastuzumab-based treatment. The goal is to understand how common cardiac problems are in this group of patients at high risk. The smaller cohort (currently closed to accrual) is randomized. Patients in this second cohort are randomized to either carvedilol or no treatment, with the goal of seeing whether carvedilol (used to treat heart failure and high blood pressure) may prevent the heart from side effects of chemotherapy.

Recruiting

2 awards

Phase 3

23 criteria

Hormone Therapy with or without Radiation

for Breast Cancer

This Phase III Trial evaluates whether breast conservation surgery and endocrine therapy results in a non-inferior rate of invasive or non-invasive ipsilateral breast tumor recurrence (IBTR) compared to breast conservation with breast radiation and endocrine therapy.

Recruiting

2 awards

Phase 3

13 criteria