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St. Michael's Hospital
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TORONTO, Ontario M5B 1W8
Global Leader in Breast Cancer
Global Leader in Heart Failure
Conducts research for Cardiovascular Disease
Conducts research for Heart Attack
Conducts research for Stroke
630 reported clinical trials
54 medical researchers
Summary
St. Michael's Hospital is a medical facility located in TORONTO, Ontario. This center is recognized for care of Breast Cancer, Heart Failure, Cardiovascular Disease, Heart Attack, Stroke and other specialties. St. Michael's Hospital is involved with conducting 630 clinical trials across 853 conditions. There are 54 research doctors associated with this hospital, such as Neil Fam, MD, Ron Wald, Amit Atrey, MD, and Sakina Rizvi, PhD.
Area of expertise
Breast Cancer
St. Michael's Hospital has run 40 trials for Breast Cancer. Some of their research focus areas include:
Heart Failure
St. Michael's Hospital has run 34 trials for Heart Failure. Some of their research focus areas include:
Top PIs
Neil Fam, MD
St. Michael's Hospital
7 years of reported clinical research
Ron Wald
St. Michael's Hospital
1 year of reported clinical research
Amit Atrey, MD
St. Michael's Hospital
5 years of reported clinical research
Sakina Rizvi, PhD
St. Michael's Hospital
2 years of reported clinical research
Clinical Trials running at St. Michael's Hospital
Heart Failure
Cancer
Cardiovascular Disease
Atrial Fibrillation
Suicide
Depression
Von Willebrand Disease
Respiratory Impairment
Stroke
Mastocytosis
Stopping Heart Medications
for Cancer Survivors
Cancer therapy-related cardiac dysfunction (CTRCD) is when the heart's ability to pump oxygenated blood to the body is compromised. It is a side effect of cancer therapy which can occur as commonly as in 1 in 5 patients. When this occurs, heart failure medications are started to protect the heart from progressing to heart failure. With early detection and treatment, heart function recovers to normal in \>80% of patients. Unfortunately, heart failure medications are associated with an undesirable long-term pill burden, financial costs, and side-effects (e.g., dizziness and fatigue). As a result, cancer survivors frequently ask if they can safely stop their heart failure medications once their heart function has returned to normal. Currently there is no scientific evidence in this area of Cardio-Oncology. To address this knowledge gap, the investigators have designed a randomized control trial to assess the safety of stopping heart failure medication in patients with CTRCD and recovered heart function. The investigators will enrol patients who have completed their cancer therapy and are on heart medications for their CTRCD, which has now normalized. The investigators will randomize patients with no other reasons to continue heart failure medications (e.g., kidney disease) to continuing or stopping their heart medications safely. All patients will undergo a cardiac MRI at baseline, 1 and 5 years with safety assessments at 6-8 weeks, 6 months and 3 and 5 years. The investigators will determine if stopping medications is non-inferior to continuing medications by counting the numbers of patients who develop heart dysfunction by 1 year in each group.
Recruiting
3 awards
Phase 4
Omecamtiv Mecarbil
for Heart Failure
The purpose of this study is to find out if the investigational drug called omecamtiv mecarbil can reduce the risk of the effects of heart failure, like hospitalization, transplantation, or death in patients with heart failure and severely reduced ejection fraction.
Recruiting
1 award
Phase 3
10 criteria
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Frequently asked questions
What kind of research happens at St. Michael's Hospital?
St. Michael's Hospital is a medical facility located in TORONTO, Ontario. This center is recognized for care of Breast Cancer, Heart Failure, Cardiovascular Disease, Heart Attack, Stroke and other specialties. St. Michael's Hospital is involved with conducting 630 clinical trials across 853 conditions. There are 54 research doctors associated with this hospital, such as Neil Fam, MD, Ron Wald, Amit Atrey, MD, and Sakina Rizvi, PhD.
Where is St. Michael's Hospital located?
**Directions to St. Michael's Hospital, Toronto, Ontario:** - From the Gardiner Expressway: Exit at Yonge Street, head north, turn right onto Elm Street, and then left onto Bond Street. - From the Don Valley Parkway (DVP): Exit at Richmond Street, head west to Church Street, then south to Bond Street.
Who should I call to ask about financial aid or insurance network?
St. Michael's Hospital Avera offers financial assistance to low-income uninsured patients, covering full or partial charity adjustments, Medicaid, and other assistance programs. Eligibility and discount levels are determined with consideration for extenuating circumstances. To apply, contact the business office at 605-589-2145 or visit the hospital's website for application materials; documentation of income is required.
What insurance does St. Michael's Hospital accept?
St. Michael's Hospital accepts all private insurance plans but is not a participating provider with health benefit plans. It is included in a variety of health insurance plans including Managed Medicaid, Amerigroup, Community Health Plan of Washington, Coordinated Care, Molina, and United Healthcare. For current plan coverage and inquiries, contact your insurance company or call the member services number on your insurance card.
What awards or recognition has St. Michael's Hospital received?
St. Michael's Hospital, located in Toronto, Ontario, is renowned for its comprehensive care and research in areas such as inner city health, critical care and trauma, heart disease, neurosurgery, cancer care, care for the homeless, and global health. It has earned international recognition for its research, including prestigious Canada Research Chairs. The hospital's Research Training Centre is dedicated to fostering the development of future biomedical and health researchers.
Unbiased Results
We believe in providing patients with all the options.
Your Data Stays Your Data
We only share your information with the clinical trials you're trying to access.
Verified Trials Only
All of our trials are run by licensed doctors, researchers, and healthcare companies.
Unbiased Results
We believe in providing patients with all the options.
Your Data Stays Your Data
We only share your information with the clinical trials you're trying to access.
Verified Trials Only
All of our trials are run by licensed doctors, researchers, and healthcare companies.