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Princess Margaret Cancer Centre

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TORONTO, Ontario M5G 2M9
Global Leader in Cancer
Global Leader in Lung Cancer
Conducts research for Pancreatic Cancer
Conducts research for Breast Cancer
Conducts research for Prostate Cancer
988 reported clinical trials
71 medical researchers
Photo of Princess Margaret Cancer Centre in TORONTOPhoto of Princess Margaret Cancer Centre in TORONTO

Summary

Princess Margaret Cancer Centre is a medical facility located in TORONTO, Ontario. This center is recognized for care of Cancer, Lung Cancer, Pancreatic Cancer, Breast Cancer, Prostate Cancer and other specialties. Princess Margaret Cancer Centre is involved with conducting 988 clinical trials across 546 conditions. There are 71 research doctors associated with this hospital, such as Amit Oza, MD, Lillian Siu, MD, Marcus Butler, and Philippe Bedard.

Area of expertise

1Cancer
Global Leader
Princess Margaret Cancer Centre has run 206 trials for Cancer. Some of their research focus areas include:
Stage IV
Stage III
HER2 positive
2Lung Cancer
Global Leader
Princess Margaret Cancer Centre has run 146 trials for Lung Cancer. Some of their research focus areas include:
Stage IV
Stage III
HER2 positive

Top PIs

Clinical Trials running at Princess Margaret Cancer Centre

Breast Cancer
Cancer
Multiple Myeloma
Lung Cancer
Lymphoma
Solid Tumors
Prostate Cancer
Colorectal Cancer
Ovarian Cancer
Melanoma
Image of trial facility.

Sacituzumab Tirumotecan + Pembrolizumab

for Breast Cancer

Researchers want to know if sacituzumab tirumotecan given alone or with pembrolizumab can treat triple negative breast cancer (TNBC). The main goal of this study is to learn if people treated with sacituzumab tirumotecan alone or with pembrolizumab live longer overall or without the cancer growing or spreading compared to people treated with chemotherapy.
Recruiting2 awards Phase 33 criteria
Image of trial facility.

Sacituzumab Tirumotecan + Pembrolizumab

for Breast Cancer

The purpose of this study is to compare sacituzumab tirumotecan as a single agent, and in combination with pembrolizumab, versus Treatment of Physician's Choice (TPC) in participants with hormone receptor positive/human epidermal growth factor receptor-2 negative (HR+/HER2-) unresectable locally advanced, or metastatic, breast cancer. The primary hypotheses are that sacituzumab tirumotecan as a single agent and sacituzumab tirumotecan plus pembrolizumab are superior to TPC with respect to progression-free survival (PFS) per Response Evaluation Criteria in Solid Tumors version 1.1 (RECIST 1.1) by blinded independent central review (BICR) in all participants.
Recruiting2 awards Phase 33 criteria
Image of trial facility.

sac-TMT + Pembrolizumab

for Breast Cancer

This is a randomized, open-label study comparing the efficacy and safety of adjuvant sacituzumab tirumotecan (MK-2870) in combination with pembrolizumab compared to treatment of physician's choice (TPC) in participants with triple-negative breast cancer (TNBC) who received neoadjuvant therapy and did not achieve a pathological complete response (pCR) at surgery. The primary objective is to compare sacituzumab tirumotecan plus pembrolizumab to TPC (pembrolizumab or pembrolizumab plus capecitabine) with respect to invasive disease-free survival (iDFS) per investigator assessment. It is hypothesized that sacituzumab tirumotecan plus pembrolizumab is superior to TPC with respect to iDFS per investigator assessment.
Recruiting2 awards Phase 35 criteria

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Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Terms of Service·Privacy Policy·Cookies·Security
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Terms of Service·Privacy Policy·Cookies·Security