Neil Fam - Unity Health Toronto

Dr. Neil Fam, MD

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St. Michael's Hospital

Studies Mitral Regurgitation
Studies Mitral Valve Regurgitation
16 reported clinical trials
19 drugs studied

Affiliated Hospitals

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St. Michael's Hospital
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St Thomas Elgin General Hospital

Clinical Trials Neil Fam, MD is currently running

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Transcatheter Valve Repair

for Mitral Regurgitation

This trial tests a new device called Edwards PASCAL that fixes leaky heart valves without surgery. It is for patients who can't have surgery or haven't improved with other treatments. The device helps the valve close better, stopping blood from leaking backward.
Recruiting1 award N/A9 criteria
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Transcatheter Edge-to-Edge Repair

for Mitral Valve Regurgitation

Mitral regurgitation may be seen in the setting of cardiogenic shock. Transcatheter edge-to-edge repair (TEER) has been shown to improve outcomes in patients with chronic heart failure. Observational studies suggest improvements in clinical outcomes in patients with mitral regurgitation in the setting of cardiogenic shock; however, there remains a lack of randomized clinical data to support the use of TEER in cardiogenic shock. This study will be a multicenter, open-label, randomized-controlled trial with two study arms: medical therapy and TEER. Patients admitted to the Cardiac Intensive Care Unit (CICU), Cardiac Surgery Intensive Care Unit (CSICU) or Intensive Care Units (ICU) at participating centers will be recruited. The study aims to answer the question: "Does TEER in patients with SCAI stage C or D cardiogenic with concomitant moderate or greater mitral regurgitation improve outcomes as compared to medical therapy?" The study hypothesis is that TEER will lead to an overall improvement in the composite outcome as compared to the medical therapy arm.
Recruiting1 award N/A5 criteria

More about Neil Fam, MD

Clinical Trial Related7 years of experience running clinical trials · Led 16 trials as a Principal Investigator · 12 Active Clinical Trials
Treatments Neil Fam, MD has experience with
  • Edwards PASCAL System
  • Tendyne Mitral Valve System
  • MitraClip System
  • Transcatheter Edge-to-edge Repair
  • Medical Therapy
  • Percutaneous Coronary Intervention (PCI)

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