McMaster Children's Hospital at Hamilton Health Sciences

Summary

McMaster Children's Hospital at Hamilton Health Sciences is a medical facility located in HAMILTON, Ontario. This center is recognized for care of Leukemia, Brain Tumor, Cancer, Acute Lymphoblastic Leukemia, Neuroblastoma and other specialties. McMaster Children's Hospital at Hamilton Health Sciences is involved with conducting 235 clinical trials across 470 conditions. There are 11 research doctors associated with this hospital, such as Uma H. Athale, Luis Braga, MD, Jeffrey Pernica, MD, and Michelle Batthish, MD.

Top PIs

Clinical Trials running at McMaster Children's Hospital at Hamilton Health Sciences

Brain Tumor

Testicular cancer

Neuroblastoma

Community-acquired Pneumonia

Ovarian Carcinoma

Ovarian Tumors

Testicular Carcinoma

Ovarian Choriocarcinoma

Cancer

Langerhans Cell Histiocytosis

Selinexor + Radiation

for Brain Cancer

This trial tests the safety and effectiveness of combining selinexor with radiation therapy in children and young adults with aggressive brain tumors. Selinexor is a drug that blocks a protein to stop cancer cells from growing. The study aims to find the best dose and see if this combination can shrink tumors.

Recruiting

1 award

Phase 1 & 2

1 criteria

Lower Radiotherapy Dose

for Brain Tumors

This phase II trial studies how well lower dose radiotherapy after chemotherapy (Carboplatin \& Etoposide) works in treating children with central nervous system (CNS) germinomas. Radiation therapy uses high energy x-rays, particles, or radioactive seeds to kill cancer cells and shrink tumors. Carboplatin is in a class of medications known as platinum-containing compounds. It works in a way similar to the anticancer drug cisplatin, but may be better tolerated than cisplatin. Carboplatin works by killing, stopping or slowing the growth of tumor cells. Etoposide is in a class of medications known as podophyllotoxin derivatives. It blocks a certain enzyme needed for cell division and DNA repair and may kill cancer cells. Researchers want to see if lowering the dose of standard radiotherapy (RT) after chemotherapy can help get rid of CNS germinomas with fewer long-term side effects.

Recruiting

1 award

Phase 2

10 criteria

Health Information Collection

for Childhood Cancer

This study gathers health information for the Project: Every Child for younger patients with cancer. Gathering health information over time from younger patients with cancer may help doctors find better methods of treatment and on-going care.

Recruiting

1 award

N/A

10 criteria