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HAMILTON

Juravinski Cancer Centre

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HAMILTON, Ontario L8V 5C2

Global Leader in Breast Cancer

Global Leader in Prostate Cancer

Conducts research for Cancer

Conducts research for Lung Cancer

Conducts research for Ovarian Cancer

474 reported clinical trials

26 medical researchers

Photo of Juravinski Cancer Centre in HAMILTONPhoto of Juravinski Cancer Centre in HAMILTONPhoto of Juravinski Cancer Centre in HAMILTON

Summary

Juravinski Cancer Centre is a medical facility located in HAMILTON, Ontario. This center is recognized for care of Breast Cancer, Prostate Cancer, Cancer, Lung Cancer, Ovarian Cancer and other specialties. Juravinski Cancer Centre is involved with conducting 474 clinical trials across 379 conditions. There are 26 research doctors associated with this hospital, such as Peter Gross, Jeffrey N. Greenspoon, Timothy J. Whelan, and Som Mukherjee, MD.

Area of expertise

1

Breast Cancer

Global Leader

Juravinski Cancer Centre has run 70 trials for Breast Cancer. Some of their research focus areas include:

Stage IV
HER2 negative
Stage II
2

Prostate Cancer

Global Leader

Juravinski Cancer Centre has run 62 trials for Prostate Cancer. Some of their research focus areas include:

Stage IV
GRPR positive
Stage I

Top PIs

Clinical Trials running at Juravinski Cancer Centre

Cancer

Lung Cancer

Breast Cancer

Multiple Myeloma

Prostate Cancer

Pancreatic Cancer

Melanoma

Acute Myeloid Leukemia

Non-Small Cell Lung Cancer

Brain Tumor

Image of trial facility.

Immunotherapy + Chemotherapy

for Sarcoma

This phase III trial compares the effect of immunotherapy (pembrolizumab) plus chemotherapy (doxorubicin) to chemotherapy (doxorubicin) alone in treating patients with dedifferentiated liposarcoma (DDLPS), undifferentiated pleomorphic sarcoma (UPS) or a related poorly differentiated sarcoma that has spread from where it first started (primary site) to other places in the body (metastatic) or that cannot be removed by surgery (unresectable). Doxorubicin is in a class of medications called anthracyclines. Doxorubicin damages the cell's deoxyribonucleic acid (DNA) and may kill tumor cells. It also blocks a certain enzyme needed for cell division and DNA repair. A monoclonal antibody is a type of protein that can bind to certain targets in the body, such as molecules that cause the body to make an immune response (antigens). Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Adding immunotherapy (pembrolizumab) to the standard chemotherapy (doxorubicin) may help patients with metastatic or unresectable DDLPS, UPS or a related poorly differentiated sarcoma live longer without having disease progression.

Recruiting

2 awards

Phase 3

10 criteria

Image of trial facility.

LY4170156

for Ovarian Cancer

This is a clinical study that has two parts. It is testing a potential new medicine called Sofetabart Mipitecan (LY4170156) for people with certain types of ovarian, peritoneal, and fallopian tube cancers. Part A looks at participants whose cancer no longer responds to platinum-based treatments (a type of chemotherapy). Part B looks at participants whose cancer still responds to platinum-based treatments. The researchers want to find out if Sofetabart Mipitecan works better than the usual treatments that doctors use now and to better understand how safe it is. Each participant's time in the study will depend on how they respond to the treatment.

Recruiting

2 awards

Phase 3

4 criteria

Image of trial facility.

Pembrolizumab

for Advanced Cancers

The purpose of this study is to evaluate the long-term safety and efficacy of pembrolizumab (MK-3475) in participants from previous Merck pembrolizumab-based parent studies who transition into this extension study. This study will consist of three phases: 1) First Course Phase, 2) Survival Follow-up Phase or 3) Second Course Phase. Each participant will transition to this extension study in one of the following three phases, depending on the study phase they were in at the completion of the parent study. Participants who were in the First Course Phase of study treatment with pembrolizumab or lenvatinib in their parent study will enter the First Course Phase of this study and complete up to 35 doses or more every 3 weeks (Q3W) or 17 doses or more every 6 weeks (Q6W) of study treatment with pembrolizumab or a pembrolizumab-based combination or lenvatinib according to arm assignment. Participants who were in the Follow-up Phase in the parent study (post-treatment or Survival Follow-up Phase) will enter the Survival Follow-up Phase of this study. Participants who were in the Second Course Phase in their parent study will enter Second Course Phase of this study and complete up to 17 doses Q3W or 8 doses Q6W of study treatment with pembrolizumab or a pembrolizumab-based combination according to arm assignment. Any participant originating from a parent trial where crossover to pembrolizumab was permitted upon disease progression may be eligible for 35 doses as Q3W or 17 doses Q6W of pembrolizumab (approximately 2 years), if they progress while on the control arm and pembrolizumab is approved for the indication in the country where the potential eligible crossover participant is being evaluated.

Recruiting

2 awards

Phase 3

4 criteria

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