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Fox Chase Cancer Center

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Philadelphia, Pennsylvania 19111

Global Leader in Lung Cancer

Global Leader in Cancer

Conducts research for Pancreatic Cancer

Conducts research for Breast Cancer

Conducts research for Prostate Cancer

1153 reported clinical trials

68 medical researchers

Photo of Fox Chase Cancer Center in PhiladelphiaPhoto of Fox Chase Cancer Center in PhiladelphiaPhoto of Fox Chase Cancer Center in Philadelphia

Summary

Fox Chase Cancer Center is a medical facility located in Philadelphia, Pennsylvania. This center is recognized for care of Lung Cancer, Cancer, Pancreatic Cancer, Breast Cancer, Prostate Cancer and other specialties. Fox Chase Cancer Center is involved with conducting 1,153 clinical trials across 668 conditions. There are 68 research doctors associated with this hospital, such as Anthony J. Olszanski, Jessica Bauman, MD, Margaret von Mehren, MD, and Hossein Borghaei.

Area of expertise

1

Lung Cancer

Global Leader

Fox Chase Cancer Center has run 181 trials for Lung Cancer. Some of their research focus areas include:

Stage IV
Stage III
EGFR positive
2

Cancer

Global Leader

Fox Chase Cancer Center has run 157 trials for Cancer. Some of their research focus areas include:

Stage IV
Stage III
HER2 positive

Top PIs

Clinical Trials running at Fox Chase Cancer Center

Cancer

Lung Cancer

Skin Cancer

Prostate Cancer

Bladder Cancer

Ovarian Cancer

Solid Tumors

Multiple Myeloma

Colorectal Cancer

Breast Cancer

Image of trial facility.

Intensified Post-Surgery Monitoring

for Cancer Surgery Recovery

This is a randomized trial of intensified post-discharge surveillance (Intervention Arm) versus standard post-discharge surveillance (Control Arm).

Recruiting

2 awards

Phase 3

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Pembrolizumab

for Advanced Cancers

The purpose of this study is to evaluate the long-term safety and efficacy of pembrolizumab (MK-3475) in participants from previous Merck pembrolizumab-based parent studies who transition into this extension study. This study will consist of three phases: 1) First Course Phase, 2) Survival Follow-up Phase or 3) Second Course Phase. Each participant will transition to this extension study in one of the following three phases, depending on the study phase they were in at the completion of the parent study. Participants who were in the First Course Phase of study treatment with pembrolizumab or lenvatinib in their parent study will enter the First Course Phase of this study and complete up to 35 doses or more every 3 weeks (Q3W) or 17 doses or more every 6 weeks (Q6W) of study treatment with pembrolizumab or a pembrolizumab-based combination or lenvatinib according to arm assignment. Participants who were in the Follow-up Phase in the parent study (post-treatment or Survival Follow-up Phase) will enter the Survival Follow-up Phase of this study. Participants who were in the Second Course Phase in their parent study will enter Second Course Phase of this study and complete up to 17 doses Q3W or 8 doses Q6W of study treatment with pembrolizumab or a pembrolizumab-based combination according to arm assignment. Any participant originating from a parent trial where crossover to pembrolizumab was permitted upon disease progression may be eligible for 35 doses as Q3W or 17 doses Q6W of pembrolizumab (approximately 2 years), if they progress while on the control arm and pembrolizumab is approved for the indication in the country where the potential eligible crossover participant is being evaluated.

Recruiting

2 awards

Phase 3

4 criteria

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Immunotherapy + Chemotherapy

for Sarcoma

This phase III trial compares the effect of immunotherapy (pembrolizumab) plus chemotherapy (doxorubicin) to chemotherapy (doxorubicin) alone in treating patients with dedifferentiated liposarcoma (DDLPS), undifferentiated pleomorphic sarcoma (UPS) or a related poorly differentiated sarcoma that has spread from where it first started (primary site) to other places in the body (metastatic) or that cannot be removed by surgery (unresectable). Doxorubicin is in a class of medications called anthracyclines. Doxorubicin damages the cell's deoxyribonucleic acid (DNA) and may kill tumor cells. It also blocks a certain enzyme needed for cell division and DNA repair. A monoclonal antibody is a type of protein that can bind to certain targets in the body, such as molecules that cause the body to make an immune response (antigens). Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Adding immunotherapy (pembrolizumab) to the standard chemotherapy (doxorubicin) may help patients with metastatic or unresectable DDLPS, UPS or a related poorly differentiated sarcoma live longer without having disease progression.

Recruiting

2 awards

Phase 3

10 criteria

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