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Boston Children's Hospital

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Boston, Massachusetts 02115
Global Leader in Syndrome
Global Leader in Cystic Fibrosis
Conducts research for Fibrosis
Conducts research for Congenital Heart Defects
Conducts research for Heart Disease
1223 reported clinical trials
124 medical researchers
Photo of Boston Children's Hospital in BostonPhoto of Boston Children's Hospital in BostonPhoto of Boston Children's Hospital in Boston

Summary

Boston Children's Hospital is a medical facility located in Boston, Massachusetts. This center is recognized for care of Syndrome, Cystic Fibrosis, Fibrosis, Congenital Heart Defects, Heart Disease and other specialties. Boston Children's Hospital is involved with conducting 1,223 clinical trials across 1,288 conditions. There are 124 research doctors associated with this hospital, such as Susan Chi, MD, Katherine A. Janeway, Dr. David Brown, and Steven G. DuBois, MD, MS.

Area of expertise

1Syndrome
Global Leader
Boston Children's Hospital has run 101 trials for Syndrome. Some of their research focus areas include:
RyR2 positive
FMR1
FMR1 positive
2Cystic Fibrosis
Global Leader
Boston Children's Hospital has run 89 trials for Cystic Fibrosis. Some of their research focus areas include:
CFTR
CFTR positive
F508del

Top PIs

Clinical Trials running at Boston Children's Hospital

Ulcerative Colitis
Crohn's Disease
Inflammatory Bowel Disease
Ulcer
Type 1 Diabetes
Chronic Kidney Disease
Pulmonary Arterial Hypertension
Hypophosphatemic Rickets
Tetralogy of Fallot
Muscular Dystrophy
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Vedolizumab

for Ulcerative Colitis and Crohn's Disease

The study is an extension of two parent studies (MLN0002-3024 [NCT04779307] and MLN0002-3025 [NCT04779320]). Participants must have participated in one of the previous studies. The purpose of this study is to collect the long-term safety of vedolizumab in children with UC or CD.
Recruiting3 awards Phase 3
Image of trial facility.

Mirikizumab

for Pediatric Ulcerative Colitis

The main purpose of this study is to investigate efficacy, pharmacokinetics and safety of the drug in pediatric participants with moderately to severely active ulcerative colitis (UC).
Recruiting2 awards Phase 3
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Upadacitinib

for Ulcerative Colitis

Ulcerative colitis (UC) is a type of inflammatory bowel disease that causes inflammation and bleeding from the lining of the rectum and colon (large intestine). This study will assess how safe and effective Upadacitinib is in treating pediatric participants with UC. Adverse events and change in disease activity will be assessed. Upadacitinib (RINVOQ) is a drug approved in adults for moderate- to severely active UC and is being developed for moderate- to severely active UC in pediatric participants. This study is conducted in 2 periods: Period 1 is comprised of two phases: an 8-week open-label induction phase which means that the study doctor and patients know that participants will receive UPA Dose-A (or the adult equivalent based on body weight) followed by a 44-week double-blind maintenance phase meaning that neither the participants nor the study doctors will know which dose of upadacitinib will be given(UPA Dose B or Dose C). Period 2 is a 260 week open-label extension (OLE) of Period 1. Approximately 110 pediatric participants with moderate to severely active UC will be enrolled at up to 100 sites worldwide. Participants will receive upadacitinib oral tablets once daily or oral solution twice daily at approximately the same time each day, with or without food. Participants will be followed up for 30 days after each phase (i.e. after induction, maintenance, OLE) and only if a participant doesn't continue into the next phase. There may be higher treatment burden for participants in this trial compared to their standard of care. Participants will attend regular visits during the study at a hospital or clinic. The effect of the treatment will be checked by medical assessments, blood tests, checking for side effects and completing questionnaires.
Recruiting2 awards Phase 3

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Frequently asked questions

What kind of research happens at Boston Children's Hospital?
Boston Children's Hospital is a medical facility located in Boston, Massachusetts. This center is recognized for care of Syndrome, Cystic Fibrosis, Fibrosis, Congenital Heart Defects, Heart Disease and other specialties. Boston Children's Hospital is involved with conducting 1,223 clinical trials across 1,288 conditions. There are 124 research doctors associated with this hospital, such as Susan Chi, MD, Katherine A. Janeway, Dr. David Brown, and Steven G. DuBois, MD, MS.
Where is Boston Children's Hospital located?
**Directions to Boston Children's Hospital:** - **By Public Transit:** Take the Green Line "D" train to the Longwood Medical Area stop. - **By Car:** Take the Massachusetts Turnpike (I-90) to Exit 22 at Copley Square/Prudential. Follow signs to Huntington Avenue and then to Longwood Avenue.
Who should I call to ask about financial aid or insurance network?
**Boston Children's Hospital Financial Assistance and Insurance Contact Information:** - **General Inquiries:** For questions related to financial assistance, billing, payment plans, and insurance matters, please call **617-355-3397**. - **Financial Assistance Applications:** For specific questions regarding financial assistance applications, contact the Financial Counseling Unit of the Patient Financial Services Department at **300 Longwood Avenue, Boston, MA, 02115**, or call **(617) 355-7201**.
What insurance does Boston Children's Hospital accept?
Boston Children's Hospital accepts a variety of insurance plans, including but not limited to: 1. Aetna 2. Blue Cross Blue Shield of Massachusetts (all products) 3. BMC Well Sense with Boston Children Hosp ACO 4. Children's Medical Security Plan 5. Allways Health Partners Commercial Plan 6. Blue Benefit's Administrators 7. Cigna 8. Fallon 9. Harvard Pilgrim Healthcare 10. United Healthcare (HMO, PPO, POS & Medicare) 11. UnitedHealthcare – Passport 12. UnitedHealthcare – Choice/Choice Plus 13. United Empire Plan Please verify your insurance coverage directly with the hospital or healthcare provider before receiving medical services.
What awards or recognition has Boston Children's Hospital received?
Boston Children's Hospital, located in Boston, Massachusetts, is the world's largest and most active pediatric research enterprise with $518 million in annual research funding. It boasts over 1,000,000 square feet of state-of-the-art laboratory space. The hospital's distinguished research community includes 13 members of the National Academy of Sciences, 28 members of the National Academy of Medicine, and four Nobel Prize winners.