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Dana Farber Cancer Institute

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Boston, Massachusetts 02215
Global Leader in Cancer
Global Leader in Breast Cancer
Conducts research for Solid Tumors
Conducts research for Lung Cancer
Conducts research for Pancreatic Cancer
3428 reported clinical trials
268 medical researchers
Photo of Dana Farber Cancer Institute in BostonPhoto of Dana Farber Cancer Institute in BostonPhoto of Dana Farber Cancer Institute in Boston

Summary

Dana Farber Cancer Institute is a medical facility located in Boston, Massachusetts. This center is recognized for care of Cancer, Breast Cancer, Solid Tumors, Lung Cancer, Pancreatic Cancer and other specialties. Dana Farber Cancer Institute is involved with conducting 3,428 clinical trials across 1,488 conditions. There are 268 research doctors associated with this hospital, such as Susan Chi, MD, Geoffrey I. Shapiro, Haeseong Park, MD, and Ryan Sullivan, MD.

Area of expertise

1Cancer
Global Leader
Dana Farber Cancer Institute has run 564 trials for Cancer. Some of their research focus areas include:
Stage IV
Stage III
HER2 negative
2Breast Cancer
Global Leader
Dana Farber Cancer Institute has run 538 trials for Breast Cancer. Some of their research focus areas include:
Stage IV
Stage III
HER2 negative

Top PIs

Clinical Trials running at Dana Farber Cancer Institute

Breast Cancer
Lung Cancer
Ovarian Cancer
Multiple Myeloma
Prostate Cancer
Cancer
Chronic Lymphocytic Leukemia
Melanoma
Brain Tumor
Testicular cancer
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Avelumab + Palbociclib/Hydroxychloroquine

for Breast Cancer

This clinical trial will assess the safety and early efficacy of Hydroxychloroquine or Avelumab, with or without Palbociclib, in early-stage ER+ breast cancer patients who are found to harbor disseminated tumor cells (DTCs) in the bone marrow after definitive surgery and standard adjuvant therapy.
Recruiting3 awards Phase 212 criteria
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CDK4/6 Inhibitors

for Metastatic Breast Cancer

The purpose of this study is to generate evidence on an alternative dosing strategy for CDK4/6 inhibitors to help more patients with Metastatic Breast Cancer (MBC) (age ≥ 65 years) tolerate side effects and stay on treatment longer, to derive the most clinical benefit from these drugs. The primary objective of the CDK Study is to compare time to treatment discontinuation (TTD) on the approved dosing for palbociclib (125 mg orally daily on days 1-21 of 28-day cycle) or ribociclib (600 mg orally daily on days 1-21 of 28-day cycle) vs. TTD using titrated dosing approach with the same schedule but starting at a lower dose of palbociclib (100 mg or 75 mg) or ribociclib (400 mg or 200 mg) and escalating the dose if well-tolerated in combination with provider/patient choice endocrine therapy (aromatase inhibitor (AI) or fulvestrant) in patients age 65 or older with HR+/HER2- MBC. The secondary and exploratory objectives will generate evidence needed to personalize treatment decisions by comparing patient-centric secondary outcomes and evaluating baseline factors. Together with their treating physician, participants will choose the CDK4/6 inhibitor (palbociclib or ribociclib) and which endocrine therapy (aromatase inhibitor or fulvestrant) of their choice but will be randomized to either Arm 1 (indicated dosing) or Arm 2 (titrated dosing). Note: Telehealth visits are allowed at any time per institutional guidelines. In addition, the study allows for remote consenting per institutional guidelines.
Recruiting2 awards Phase 33 criteria
Image of trial facility.

Giredestrant vs. Fulvestrant

for Advanced Breast Cancer

This trial is testing two drug combinations to treat a specific type of advanced breast cancer that no longer responds to standard hormone treatments. The goal is to see which combination works better by stopping the cancer cells from growing.
Recruiting2 awards Phase 38 criteria

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Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Terms of Service·Privacy Policy·Cookies·Security
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Terms of Service·Privacy Policy·Cookies·Security