Katherine A. Janeway, MD, MMSc - Dana ...

Dr. Katherine A. Janeway

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Dana-Farber Cancer Institute

Expert in Osteosarcoma
Expert in Bone Cancer
15 reported clinical trials
25 drugs studied

Area of expertise

1

Osteosarcoma

Global Leader

Katherine A. Janeway has run 13 trials for Osteosarcoma. Some of their research focus areas include:

Stage IV
Stage I
Stage II
2

Bone Cancer

Global Leader

Katherine A. Janeway has run 11 trials for Bone Cancer. Some of their research focus areas include:

Stage I
Stage II
MTOR positive

Affiliated Hospitals

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Dana Farber Cancer Institute

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Massachusetts General Hospital Cancer Center

Clinical Trials Katherine A. Janeway is currently running

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Cabozantinib + Chemotherapy

for Bone Cancer

This phase II/III trial tests the safety, side effects, and best dose of the drug cabozantinib in combination with standard chemotherapy, and to compare the effect of adding cabozantinib to standard chemotherapy alone in treating patients with newly diagnosed osteosarcoma. Cabozantinib is in a class of medications called kinase inhibitors which block protein signals affecting new blood vessel formation and the ability to activate growth signaling pathways. This may help slow the growth of tumor cells. The drugs used in standard chemotherapy for this trial are methotrexate, doxorubicin, and cisplatin (MAP). Methotrexate stops cells from making DNA and may kill tumor cells. It is a type of antimetabolite. Doxorubicin is in a class of medications called anthracyclines. It works by slowing or stopping the growth of tumor cells in the body. Cisplatin is in a class of medications known as platinum-containing compounds. It works by killing, stopping or slowing the growth of tumor cells. Adding cabozantinib to standard chemotherapy may work better in treating newly diagnosed osteosarcoma.

Recruiting

1 award

Phase 2 & 3

10 criteria

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Thoracotomy vs Thoracoscopy

for Metastatic Osteosarcoma

This phase III trial compares the effect of open thoracic surgery (thoracotomy) to thoracoscopic surgery (video-assisted thoracoscopic surgery or VATS) in treating patients with osteosarcoma that has spread to the lung (pulmonary metastases). Open thoracic surgery is a type of surgery done through a single larger incision (like a large cut) that goes between the ribs, opens up the chest, and removes the cancer. Thoracoscopy is a type of chest surgery where the doctor makes several small incisions and uses a small camera to help with removing the cancer. This trial is being done evaluate the two different surgery methods for patients with osteosarcoma that has spread to the lung to find out which is better.

Recruiting

2 awards

Phase 3

7 criteria

More about Katherine A. Janeway

Clinical Trial Related

8 years of experience running clinical trials · Led 15 trials as a Principal Investigator · 2 Active Clinical Trials

Treatments Katherine A. Janeway has experience with

  • Olaparib
  • Palbociclib
  • Selpercatinib
  • Tipifarnib
  • Vemurafenib
  • Ceralasertib

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