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Exercise Intensity for Cardiorespiratory Fitness (REVISE Trial)

N/A
Recruiting
Led By Robert Ross, PhD
Research Sponsored by Queen's University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up measured at baseline 16 and 32 weeks.
Awards & highlights

REVISE Trial Summary

This trial will investigate whether exercise intensity/amount can improve cardiorespiratory fitness & cardiometabolic risk for adults, & whether those who don't respond will need alternative strategies.

Who is the study for?
This trial is for adults who lead a sedentary lifestyle, exercising no more than once a week, have had a stable weight for the past 6 months, and have a BMI between 20-40. It's not suitable for individuals with diabetes, current smokers, those planning to move soon or anyone with physical impairments that make exercise difficult or unsafe.Check my eligibility
What is being tested?
The study is testing how different amounts and intensities of exercise affect cardiorespiratory fitness and cardiometabolic risk factors. Participants will be assigned to one of three groups: low amount/low intensity exercise, low amount/high intensity exercise, or high amount/high intensity exercise.See study design
What are the potential side effects?
While this trial involves physical activity which typically has minimal side effects compared to drug treatments, participants may experience muscle soreness, fatigue or injury related to the exercises prescribed in the intervention.

REVISE Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~measured at baseline, 16 and 32 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and measured at baseline, 16 and 32 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Cardiorespiratory Fitness
Secondary outcome measures
Change in abdominal fat
Change in blood lipids
Change in body fat
+7 more

REVISE Trial Design

4Treatment groups
Experimental Treatment
Active Control
Group I: Low amount, low intensity exerciseExperimental Treatment1 Intervention
exercise dose (amount and intensity) will be controlled.
Group II: Low amount, high intensity exerciseExperimental Treatment1 Intervention
exercise dose (amount and intensity) will be controlled.
Group III: High amount, high intensity exerciseExperimental Treatment1 Intervention
exercise dose (amount and intensity) will be controlled.
Group IV: ControlActive Control1 Intervention
no exercise intervention

Find a Location

Who is running the clinical trial?

Queen's UniversityLead Sponsor
369 Previous Clinical Trials
121,350 Total Patients Enrolled
Robert Ross, PhDPrincipal InvestigatorQueen's University
4 Previous Clinical Trials
664 Total Patients Enrolled

Media Library

High amount, high intensity exercise Clinical Trial Eligibility Overview. Trial Name: NCT05496751 — N/A
Exercise Research Study Groups: High amount, high intensity exercise, Low amount, high intensity exercise, Control, Low amount, low intensity exercise
Exercise Clinical Trial 2023: High amount, high intensity exercise Highlights & Side Effects. Trial Name: NCT05496751 — N/A
High amount, high intensity exercise 2023 Treatment Timeline for Medical Study. Trial Name: NCT05496751 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there opportunities to participate in this research at the present time?

"Affirmative. There is information available on clinicaltrials.gov that provides evidence of this study's search for participants, which began on September 30th 2022 and was updated most recently on the 29th of that same month. The trial requires 200 individuals to take part at one site."

Answered by AI

Am I qualified to partake in this research study?

"200 people from the age range of 25 to 65 who have average cardiorespiratory fitness are being sought by this trial. The most pertinent criteria includes a body mass index between 20 and 40 kg/m2, no weight changes in excess of 2kg for 6 months before enrolment, and an inactive lifestyle (less than one day per week exercise)."

Answered by AI

Does this clinical experiment accept individuals above the age of fifty?

"This medical trial is looking to include individuals aged between 25 and 65 years old."

Answered by AI

What is the total number of participants for this research project?

"Indeed, the clinicaltrials.gov listing for this trial says that recruitment of participants is ongoing. It was first uploaded on September 30th 2022 and last adjusted on September 29th 2022. The research team must source 200 patients from one location to complete their study."

Answered by AI
Recent research and studies
clinicaltrials.govStudy
Response Variability to Exercise
Robert Ross, PhD 2022. "Response Variability to Exercise". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05496751.
~89 spots leftby Sep 2025
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