Tyrosol + Creatine for Endurance and Strength
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial explores how tyrosol (a natural compound) and creatine (a supplement often used to enhance muscle strength), both individually and combined, affect endurance, strength, and stamina. Researchers aim to determine if taking both supplements together yields better results than taking each one alone or a placebo (a harmless pill with no active ingredients). The 4-week study includes physical tests such as running a mile and lifting weights to measure changes. The trial seeks active individuals who exercise at least twice a week and have good cardiovascular fitness. Participants should not currently use supplements like creatine or those that boost muscle strength.
As an unphased trial, this study offers a unique opportunity to contribute to understanding how natural compounds and supplements can enhance physical performance.
Will I have to stop taking my current medications?
The trial requires you to stop taking any supplements that may increase muscle strength or endurance, like protein formulas, creatine, or amino acids. If you're on prescription medications that might affect exercise adaptation, you may not be eligible to participate.
Is there any evidence suggesting that this trial's treatments are likely to be safe?
Research has shown that creatine is usually safe for most people, with some studies suggesting it might help protect the heart, muscles, and nerves. Most users do not experience serious side effects.
Tyrosol, however, requires some caution. It might cause mild skin or eye irritation and could irritate the lungs if inhaled. These effects are generally mild and can be avoided with proper use. More information is needed about its effects when taken as a supplement.
Since this trial involves both tyrosol and creatine, these points are important to consider. Creatine is known to be safe, but less is known about tyrosol. Using them together might be safe, but monitoring for any reactions is crucial. Participants should report any unusual symptoms to the study team.12345Why are researchers excited about this trial's treatments?
Researchers are excited about the combination of Tyrosol and Creatine for enhancing endurance and strength because it introduces a novel approach to athletic performance. Unlike traditional supplements that often focus on a single mechanism, this combination leverages the muscle-building properties of creatine along with the antioxidant benefits of Tyrosol. Creatine supports muscle energy production, while Tyrosol, derived from olive oil, may help reduce oxidative stress and inflammation. This dual-action approach has the potential to deliver enhanced performance benefits and quicker recovery times, setting it apart from standard creatine-only supplements.
What evidence suggests that this trial's treatments could be effective for endurance and strength?
This trial will evaluate the effects of combining Tyrosol and Creatine on endurance and strength. Research has shown that this combination can significantly enhance both endurance and strength. One study found that endurance increased by 51.5% more with the combination than with Creatine alone. Additionally, participants taking both supplements completed over five times more exercise than those taking only Creatine. Tyrosol, found in olive oil, supports healthy blood flow and reduces inflammation. Creatine is already known for boosting muscle strength and energy. Together, they may offer greater benefits for endurance and reduce fatigue. Participants in this trial will be assigned to different groups: Tyrosol and Creatine together, Tyrosol with a placebo, Creatine with a placebo, or a double placebo group.678910
Who Is on the Research Team?
Eric Sikorski, PhD
Principal Investigator
Applied Science and Performance Institute
Are You a Good Fit for This Trial?
Healthy adults aged 18-50 who are moderately active at least twice a week, with good cardiovascular fitness (VO2 max in the top 50% for their age). They must not have had recent injuries or surgeries, be non-smokers and light drinkers, and avoid other supplements that affect muscle strength or endurance during the study. Women must share menstrual cycle information.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Baseline Testing
Participants undergo a series of baseline tests including body composition, cognitive testing, strength testing, and endurance testing
Treatment
Participants receive daily supplementation of tyrosol, creatine, or placebo for 4 weeks
Post-Treatment Testing
All baseline measures are repeated to assess the effects of the supplementation
Follow-up
Participants are monitored for recovery and any adverse events post-treatment
What Are the Treatments Tested in This Trial?
Interventions
- Creatine
- Tyrosol
Find a Clinic Near You
Who Is Running the Clinical Trial?
Applied Science & Performance Institute
Lead Sponsor