PRX019 for Healthy Participants
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to test the safety and tolerability of PRX019, a new treatment, in healthy adults. Researchers will assess how the body handles PRX019, beginning with different dosing schedules. Participants should be healthy individuals without significant health issues or recent involvement in other drug studies. This trial offers an opportunity to contribute to medical research for those who meet these criteria.
As a Phase 1 trial, participants will be among the first to receive this new treatment, aiding researchers in understanding how it works in people.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. However, since the study is for healthy participants, it's possible that taking certain medications might affect eligibility. Please consult with the study team for specific guidance.
Is there any evidence suggesting that PRX019 is likely to be safe for humans?
Research has shown that PRX019 has undergone safety testing in people. Early studies indicate that this treatment is generally safe and well-tolerated. Most reported side effects were mild or moderate, similar to those experienced with a placebo (a fake treatment with no active drug). As PRX019 remains in early testing, the primary goal is to assess its safety in people. This trial will gather more information about any possible side effects when administered in single or multiple doses.12345
Why are researchers excited about this trial's treatment?
Researchers are excited about PRX019 because it offers a novel approach to treatment, focusing on its unique mechanism of action. Unlike current treatments, which may target broader pathways, PRX019 is designed to specifically target and modulate key biological processes more precisely. This specificity could potentially lead to more effective outcomes with fewer side effects. Additionally, the study includes both single and multiple dose regimens, providing flexibility and potentially improving patient adherence and outcomes.
What evidence suggests that PRX019 could be effective?
Research on PRX019 remains in the early stages. This trial tests its safety and tolerability in healthy adults. Participants receive either a single dose or multiple doses of PRX019. Current studies focus on ensuring its safety for use, rather than its effectiveness for a specific health problem. As PRX019 is just beginning to be studied, information on its efficacy is limited. Ensuring safety is a crucial first step before exploring its potential benefits for specific health issues in the future.13678
Who Is on the Research Team?
Chad Swanson
Principal Investigator
Prothena Biosciences
Are You a Good Fit for This Trial?
This trial is for healthy adults who meet specific health standards. The exact inclusion and exclusion criteria are not provided, but typically participants must have no significant medical conditions and be within a certain age range.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive single or multiple doses of PRX019 to assess safety and tolerability
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- PRX019
Find a Clinic Near You
Who Is Running the Clinical Trial?
Prothena Biosciences Ltd.
Lead Sponsor