AIRWISE Intervention for Cardiovascular Disease

Overseen By Ethan S Walker, PhD

Age: 18+

Sex: Any

Trial Phase: Academic

Sponsor: University of Montana

Disqualifiers: Smoking, HEPA use, Moving, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: 2

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to evaluate the implementation of an indoor air quality program, called AIRWISE, designed to reduce air pollution inside homes. The program involves using air filters, providing education, and offering advice on behaviors to improve air quality. It targets adults aged 55 and older who reside in one home most of the week and have internet access. Participants should not currently smoke or use high-efficiency air filters at home. The goal is to determine if these strategies can raise awareness and encourage better habits for cleaner indoor air. As an unphased trial, this study allows participants to contribute to innovative research that could lead to healthier living environments.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications. It focuses on improving indoor air quality and does not mention medication changes.

What prior data suggests that the AIRWISE intervention is safe for improving indoor air quality?

Research shows that the AIRWISE program aims to improve indoor air quality by using portable air cleaners and providing education. The goal is to reduce exposure to air pollution and increase awareness. As an environmental program, it involves no drugs or medical procedures, eliminating the risk of side effects associated with medication.

Previous studies have found that similar programs using portable air cleaners are well-received. Participants did not report any negative effects from the air quality tools. Instead, they often noticed benefits like easier breathing and fewer allergy symptoms.

Because the AIRWISE program focuses on education and air filtration, it is expected to be safe for participants. The study will examine how effectively people use the program and its tools, aiming to improve understanding of air quality and health outcomes. ^{1 2 3 4 5}

Why are researchers excited about this trial?

Researchers are excited about the AIRWISE intervention for cardiovascular disease because it targets air pollution, a major but often overlooked risk factor for heart problems. Unlike traditional treatments that focus on medication or lifestyle changes to manage symptoms, AIRWISE aims to reduce exposure to harmful air pollutants, potentially preventing cardiovascular issues before they start. This proactive approach could offer a new layer of protection for heart health, complementing existing treatments like medications and lifestyle adjustments. By tackling environmental factors directly, AIRWISE has the potential to significantly enhance overall cardiovascular care and prevention strategies.

What evidence suggests that the AIRWISE intervention is effective for improving indoor air quality?

Research shows that air pollution can harm heart health, leading to issues like asthma attacks and heart problems. In this trial, the AIRWISE program aims to improve indoor air quality by using portable air cleaners and educating participants about air quality. This approach helps people understand and follow air quality measures more effectively. Although data on the AIRWISE program is limited, studies have shown that air filters can reduce harmful indoor air pollution. Therefore, researchers believe that AIRWISE might improve heart health by making the air cleaner. ^{1 2 3 6 7}

Are You a Good Fit for This Trial?

This trial is for adults over 20 who've had a recent heart procedure called percutaneous coronary intervention at the Providence Heart Institute. They must live in one place most of the week, have electricity, an email address, and internet or cell service to participate in surveys.

Inclusion Criteria

I am 20 years old or older.

I had a heart procedure at Providence Heart Institute.

I live in one place most of the week.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Intervention

Participants receive the AIRWISE intervention, which includes air filtration, education, and behavioral recommendations

6 months

Electronic surveys every 2 weeks

Follow-up

Participants are monitored for safety and effectiveness after the intervention

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

• AIRWISE

Trial Overview The AIRWISE study tests an indoor air pollution intervention that includes air filtration systems, education, and behavior tips aimed at improving heart patients' health. All participants will try this approach to see if it's accepted and used effectively.

How Is the Trial Designed?

Group I: Air pollution intervention implementation Experimental Treatment 1 Intervention

AIRWISE intervention implementation

Who Is Running the Clinical Trial?

University of Montana

Lead Sponsor

Trials

29

Recruited

4,700+

Providence Heart Institute

Collaborator

Trials

1

Recruited

20+

Published Research Related to This Trial

In a study of over 214,000 patients, 55.8% reported using a wearable device for health tracking, indicating that these devices are widely adopted among individuals receiving cardiovascular care.

Most non-users (95.3%) expressed willingness to use a wearable device if provided for free, and nearly all respondents (98%) were open to sharing their device data for health research, highlighting a strong interest in integrating wearable technology into healthcare.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Characteristics and Attitudes of Wearable Device Users and Non-Users in a Large Healthcare System. Venn, RA., Khurshid, S., Grayson, M., et al.[2023]

An integrative review of 15 articles found that educational technologies, particularly those implemented as year-long programs, significantly improved cardiovascular health outcomes in adults, including reductions in blood pressure and weight.

The most effective programs utilized playful technologies, such as storytelling and smartphone applications, leading to decreased hospitalizations and increased longevity.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

[Educational technologies designed to promote cardiovascular health in adults: integrative review]. Souza, AC., Moreira, TM., Borges, JW.[2019]

Continuous monitoring of health indicators through wearable devices can significantly improve the assessment and management of cardiovascular diseases, which currently claim 18 million lives annually.

The review highlights three key areas for monitoring: physical activity, indoor home environments, and physiological parameters, each offering unique advantages and challenges for patient care.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Continuous Monitoring of Health and Mobility Indicators in Patients with Cardiovascular Disease: A Review of Recent Technologies. Shiwani, MA., Chico, TJA., Ciravegna, F., et al.[2023]

Smart wearables, like fitness bands and smartwatches, can continuously monitor heart health through photoplethysmography, which measures the arterial pulse wave influenced by cardiovascular function.

The survey highlights the potential of these devices to detect cardiovascular disease early and emphasizes the need for further research to fully harness their capabilities in clinical settings.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Wearable Photoplethysmography for Cardiovascular Monitoring. Charlton, PH., Kyriaco, PA., Mant, J., et al.[2023]

Wearable physical activity monitoring devices significantly increase daily walking activity in patients with cardiovascular disease (CVD), with a notable effect size of 0.85 based on a systematic review of 16 randomized controlled trials.

The most substantial improvements in daily steps were observed in interventions lasting less than 3 months, suggesting that shorter-term use of these devices may be more effective for enhancing physical activity in CVD patients.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Impact of wearable device-based interventions with feedback for increasing daily walking activity and physical capacities in cardiovascular patients: a systematic review and meta-analysis of randomised controlled trials. Heizmann, AN., Chapelle, C., Laporte, S., et al.[2023]

Mobile applications for cardiovascular disease self-management have shown effectiveness in improving various health outcomes, such as reducing rehospitalization rates and enhancing quality of life among 607 patients across 10 studies.

Key features of successful apps included tracking healthy behaviors and personalized content, but the overall evidence quality was low, highlighting the need for larger, longer-term studies to confirm these findings.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Effectiveness, acceptability and usefulness of mobile applications for cardiovascular disease self-management: Systematic review with meta-synthesis of quantitative and qualitative data. Coorey, GM., Neubeck, L., Mulley, J., et al.[2022]

Consumer technologies for monitoring cardiovascular health have expanded from exercise tracking to include various physiological measurements, reflecting a growing public interest in their potential to identify and manage cardiovascular diseases.

The review assesses the accuracy and validation of these devices, suggesting that when used correctly, they could enhance healthcare delivery and support research in conditions like hypertension and heart failure.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Wearable technology and the cardiovascular system: the future of patient assessment. Williams, GJ., Al-Baraikan, A., Rademakers, FE., et al.[2023]

This review aims to evaluate how effective activity-monitoring devices and mobile applications are in improving physical activity and health outcomes for patients with cardiovascular disease undergoing cardiac rehabilitation, highlighting their potential role in supporting long-term exercise habits.

The review will analyze systematic reviews and meta-analyses of randomized controlled trials, ensuring a comprehensive assessment of the impact of these technologies on patient outcomes, with a focus on varying effectiveness based on patient characteristics and rehabilitation stages.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Effectiveness of activity-monitoring devices in patients with cardiovascular disease participating in cardiac rehabilitation programs: an umbrella review protocol. Dafny, HA., Champion, S., Gebremichael, LG., et al.[2023]

A 6-week pedometer-based telephone intervention significantly increased physical activity levels in 215 cardiac patients who did not attend a cardiac rehabilitation program, with improvements in total activity time and walking sessions observed at both 6 weeks and 6 months.

This intervention could serve as an effective and accessible alternative for enhancing physical activity in cardiac patients post-hospitalization, potentially leading to major health benefits.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Randomised controlled trial of a pedometer-based telephone intervention to increase physical activity among cardiac patients not attending cardiac rehabilitation. Furber, S., Butler, L., Phongsavan, P., et al.[2022]

Citations

1. clinicaltrials.gov clinicaltrials.gov/study/NCT06384625

Developing and Evaluating an Indoor Air Pollution ... The central study hypothesis is that an intervention program with educational strategies and visual behavioral cues will increase knowledge and awareness of air ...

2. centerwatch.com centerwatch.com/clinical-trials/listings/NCT06384625/developing-and-evaluating-an-indoor-air-pollution-intervention-among-cardiovascular-patients-the-airwise-study?state=MT&city=Missoula

the AIRWISE Study | Clinical Research Trial Listing The central study hypothesis is that an intervention program with educational strategies and visual behavioral cues will increase knowledge and ...

3. reporter.nih.gov reporter.nih.gov/project-details/11097637

Wildfires and Cardiovascular Health - NIH RePORTER The AIRWISE intervention utilizes portable air cleaners (PACs) to filter indoor air with enhanced aspects focusing on improving PAC compliance. Key components ...

4. reporter.nih.gov reporter.nih.gov/search/Sz95MmEj-Uu3HV2keOw4Nw/project-details/10872312

Project Details Project Summary/Abstract This project aims to develop new analytic tools for understanding accumulation patterns of physical activity (PA), ...

5. stacks.cdc.gov stacks.cdc.gov/view/cdc/116882/cdc_116882_DS1.pdf

Improving Use of an Existing Air Quality and Health Tool An extensive body of scientific evidence shows that exposure to air pollution can cause cardiovascular effects, including asthma attacks, heart ...

6. stacks.cdc.gov stacks.cdc.gov/view/cdc/116882

Improving Use of an Existing Air Quality and Health Tool Exposure to air pollutants is a significant health risk for individuals with asthma, cardiovascular disease, and chronic obstructive pulmonary ...

7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov/articles/PMC11621042/

Enhancing cardiovascular patients' knowledge of air pollution This study aims to evaluate the effectiveness of an educational intervention within a cardiac rehabilitation (CR) context in enhancing patients' understanding ...