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Neuroprosthetic Device

Neuroprosthetic System for Spinal Cord Injury (NNP-UE+T Trial)

N/A
Recruiting
Research Sponsored by Kevin Kilgore
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Age > 16 years
Diagnosis of cervical level spinal cord injury, either complete or incomplete; International Standards for Neurological Classification of Spinal Cord Injury (INCSCI) motor level of C4 through C8; American Spinal Injury Impairment Scale (AIS) grade A, B, C, or D; six months or more post-injury
Timeline
Screening 3 weeks
Treatment Varies
Follow Up three months post-implant
Awards & highlights

NNP-UE+T Trial Summary

This trial is to test a new, fully implanted device that could help people with cervical spinal cord injuries regain hand function, reach, and trunk function. It is funded by the FDA, NIH, and NINDS.

Who is the study for?
This trial is for individuals over 16 years old with cervical spinal cord injuries (C4-C8 level, AIS grade A-D) who are at least six months post-injury. Participants must have some arm and trunk muscle strength, be medically stable for surgery, and willing to participate. Pregnant women, those with certain neurological conditions or severe diseases, active infections, or other implantable devices are excluded.Check my eligibility
What is being tested?
The study tests a fully implanted neuroprosthetic system designed to restore hand function, reach ability, and trunk control in people with cervical spinal cord injuries. It aims to evaluate the device's effectiveness in improving motor functions that were affected by the injury.See study design
What are the potential side effects?
While specific side effects aren't listed here, potential risks may include surgical complications like infection or bleeding; device malfunction; discomfort; adverse reactions from the body towards the implant; and possible interference with other electronic devices.

NNP-UE+T Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I am older than 16 years.
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I have a spinal cord injury at the neck level and it's been over 6 months since the injury.
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I have a spinal cord injury at the neck level and it's been over 6 months since the injury.
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I can move my arms against some resistance.
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I have a spinal cord injury at the neck level and it's been 6 months since my injury.
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My arm and trunk muscles respond well to stimulation.
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I can move my arm and some upper body muscles with some strength.
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I can move my arm against gravity.
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I am medically cleared for surgery.
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I can move my arm and some upper body muscles with some strength.
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I am older than 16 years.
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I am medically cleared for surgery.

NNP-UE+T Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~pre-implant and three months post-implant
This trial's timeline: 3 weeks for screening, Varies for treatment, and pre-implant and three months post-implant for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Activities of Daily Living Abilities Test
Secondary outcome measures
Grasp-Release Test

NNP-UE+T Trial Design

1Treatment groups
Experimental Treatment
Group I: Intervention - implant neuroprosthesisExperimental Treatment1 Intervention
Receives implanted networked neuroprosthetic system for hand, arm, and trunk function. Undergoes functional training and assessment.

Find a Location

Who is running the clinical trial?

National Institute of Neurological Disorders and Stroke (NINDS)NIH
1,337 Previous Clinical Trials
648,814 Total Patients Enrolled
Case Western Reserve UniversityOTHER
299 Previous Clinical Trials
260,064 Total Patients Enrolled
Congressionally Directed Medical Research ProgramsFED
47 Previous Clinical Trials
7,019 Total Patients Enrolled

Media Library

Networked Neuroprosthetic System for Grasp and Trunk (Neuroprosthetic Device) Clinical Trial Eligibility Overview. Trial Name: NCT02329652 — N/A
Spinal Cord Injury Research Study Groups: Intervention - implant neuroprosthesis
Spinal Cord Injury Clinical Trial 2023: Networked Neuroprosthetic System for Grasp and Trunk Highlights & Side Effects. Trial Name: NCT02329652 — N/A
Networked Neuroprosthetic System for Grasp and Trunk (Neuroprosthetic Device) 2023 Treatment Timeline for Medical Study. Trial Name: NCT02329652 — N/A
Spinal Cord Injury Patient Testimony for trial: Trial Name: NCT02329652 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are applicants able to apply to this experiment currently?

"Affirmative. The clinical trial database indicates that this research program, which was first opened on December 1st 2014, is currently seeking participants. Around 10 individuals will be necessary to enrol at a single site."

Answered by AI

To what extent is this medical investigation being conducted by participants?

"Affirmative. The information hosted on clinicaltrials.gov confirms that this medical study, which was initially announced on December 1st 2014, is actively searching for participants. At present 10 patients are required from a single site."

Answered by AI

Who else is applying?

What state do they live in?
Pennsylvania
Louisiana
What site did they apply to?
MetroHealth Medical Center
What portion of applicants met pre-screening criteria?
Met criteria
Did not meet criteria
How many prior treatments have patients received?
0

Why did patients apply to this trial?

I’m motivated by my children and the desire to live. There is so much more I want to do in this lifetime and giving up isn’t an option. These are just a few reasons why I contacted you.
PatientReceived no prior treatments
Recent research and studies
~4 spots leftby Aug 2025