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Electric Stimulation for Neurogenic Bladder

AS
EB
Overseen ByEduardo Bauer, MD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: The University of Texas Health Science Center, Houston
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

Trial Summary

What is the purpose of this trial?

The purpose of this study is to assess and optimize the Avation electric stimulation system output and electromyography (EMG) processing to stimulate the tibial nerve in people with chronic Spinal Cord Injury (SCI) who have foot muscle atrophy and edema, both of which may affect proper device operations, to evaluate the safety, feasibility, and effectiveness of Avation Electric Stimulation System for bladder neuromodulation in people with SCI and identify barriers to implementation of the existing Avation Electric Stimulation System to help with developing it towards a new indication for routine care of SCI NB.

Research Team

AS

Argyrios Stampas, MD, MS

Principal Investigator

The University of Texas Health Science Center and Houston

Eligibility Criteria

This trial is for individuals with chronic Spinal Cord Injury who experience bladder control issues (neurogenic bladder). Participants should have muscle weakness or swelling in the foot, which could impact device use. Specific eligibility details are not provided.

Inclusion Criteria

No adverse events during the Vivally 5-minute trial
I use a catheter sometimes due to bladder nerve issues.
Toe flexion upon tibial nerve stimulation with transcutaneous electric stimulation
See 1 more

Exclusion Criteria

Known intolerance to leg electric stimulation
Pregnancy or breastfeeding
Known allergy to electrode or device materials
See 4 more

Timeline

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive the Avation electric stimulation system for bladder neuromodulation

12 weeks
Weekly visits for monitoring and adjustments

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

Treatment Details

Interventions

  • Vivally system stimulation
Trial Overview The study tests the Avation Electric Stimulation System's ability to stimulate the tibial nerve and improve bladder function in SCI patients. It aims to assess safety, feasibility, effectiveness, and identify barriers to its routine use.
Participant Groups
1Treatment groups
Experimental Treatment
Group I: Vivally systemExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

The University of Texas Health Science Center, Houston

Lead Sponsor

Trials
974
Recruited
361,000+

Mission Connect

Collaborator

Trials
1
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