Surgery Techniques for Ulnar Nerve Entrapment
Trial Summary
What is the purpose of this trial?
This trial aims to determine which of two surgeries is more effective in treating ulnar neuropathy at the elbow and reducing symptoms.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
What data supports the effectiveness of the treatment for ulnar nerve entrapment?
Research shows that both simple decompression and anterior transposition are effective treatments for ulnar nerve entrapment at the elbow. Studies indicate that simple decompression can be as effective as anterior transposition, especially for less severe cases, while modified submuscular transposition may be better for more severe cases.12345
Is surgery for ulnar nerve entrapment generally safe?
Research shows that surgeries like simple decompression and anterior transposition for ulnar nerve entrapment are generally safe, with improvements in nerve function observed after surgery. These techniques have been studied in many patients and are considered effective and safe for treating this condition.12345
How does the treatment for ulnar nerve entrapment differ from other treatments?
The treatment for ulnar nerve entrapment, which includes simple decompression and subcutaneous anterior transposition, is unique because it can be performed using minimally invasive techniques, such as endoscopic decompression, which may offer similar effectiveness to more invasive methods. Additionally, for mild cases (grade I), subcutaneous transposition is recommended, while more severe cases (grades II and III) may benefit more from modified submuscular transposition.12678
Research Team
Kevin Chung, MD, MS
Principal Investigator
University of Michigan
Eligibility Criteria
This trial is for people with ulnar nerve entrapment at the elbow who have tried non-surgical treatments like night splinting. They must meet specific diagnostic criteria and be able to follow study procedures. It's not for those with previous elbow surgery, other neuropathies, or conditions that make surgery too risky.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Surgery
Participants undergo one of two surgical procedures: subcutaneous anterior transposition or simple decompression
Post-Surgery Follow-up
Participants are monitored for recovery and complications at various time points
Treatment Details
Interventions
- Simple decompression
- Subcutaneous anterior transposition
Simple decompression is already approved in United States, European Union, Canada for the following indications:
- Ulnar neuropathy at the elbow (UNE)
- Cubital tunnel syndrome
- Ulnar neuropathy at the elbow (UNE)
- Cubital tunnel syndrome
- Ulnar neuropathy at the elbow (UNE)
- Cubital tunnel syndrome
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Michigan
Lead Sponsor
University of Oklahoma
Collaborator
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Collaborator
Curtis National Hand Center
Collaborator
Emory Healthcare
Collaborator
Ohio State University
Collaborator
University of Pittsburgh Medical Center
Collaborator
Norton Healthcare
Collaborator
OrthoCarolina Research Institute, Inc.
Collaborator
Wake Forest University Health Sciences
Collaborator