Behavioral Intervention for Heart Attack Rehabilitation

(ATTEND-CR Trial)

CS
CM
Overseen ByCian McCarthy, MB, BCh, BAO, SM
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Massachusetts General Hospital
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests whether the ATTEND-CR Intervention can help people attend and complete more cardiac rehabilitation sessions after a type 2 heart attack. The program includes clinician notifications and a motivational phone call to encourage attendance. Researchers compare it to the usual care received after a heart attack. Ideal participants are those who have had a type 2 heart attack, can walk without assistance, and are part of the Mass General Brigham network. As an unphased trial, this study offers a unique opportunity to contribute to innovative research that could improve cardiac rehabilitation outcomes.

What prior data suggests that this behavioral intervention is safe for heart attack rehabilitation?

Research has shown that cardiac rehabilitation (CR), including programs like ATTEND-CR, is generally safe for patients. A review of home-based cardiac rehabilitation found a very low chance of unexpected medical problems, indicating that participants usually tolerate these programs well. Another study found that individuals who complete a full CR program have a significantly lower risk of death and hospitalization. This underscores not only the safety but also the potential health benefits of participating in cardiac rehabilitation. Overall, evidence supports that CR programs are safe and beneficial for heart health.12345

Why are researchers excited about this trial?

Researchers are excited about the ATTEND-CR intervention because it takes a fresh approach to heart attack rehabilitation by focusing on behavioral change. Unlike standard care, which typically involves routine medical management and referral to cardiac rehabilitation, this intervention actively engages patients through motivational interviewing over the phone to boost their attendance at cardiac rehab sessions. By involving clinicians in sending informational messages about the importance of rehab, it aims to improve patient outcomes through enhanced participation and adherence. This innovative method could potentially transform the way post-heart attack care is delivered, making it more personalized and effective.

What evidence suggests that the ATTEND-CR intervention is effective for increasing cardiac rehabilitation attendance after a heart attack?

Research has shown that joining a cardiac rehabilitation (CR) program after a heart attack can improve health and lower the risk of another heart problem. Studies have found that attending CR can reduce the chance of death by 20% to 30% for people with coronary artery disease. However, many patients do not join these programs. In this trial, participants in the Intervention Arm will receive the ATTEND-CR intervention, which includes motivational strategies to increase participation. These strategies involve support from healthcare providers and motivational interviewing, both effective in encouraging participation in healthcare programs. By increasing CR attendance, the goal is to improve recovery and prevent future heart issues.678910

Who Is on the Research Team?

CP

Cian P McCarthy, MB, BCh, BAO, SM

Principal Investigator

Massachusetts General Hospital

Are You a Good Fit for This Trial?

Inclusion Criteria

Primary care provider (PCP) within the Mass General Brigham (MGB) network with at least one visit in the past 2 years
Ability to provide informed consent
I am 18 years old or older.
See 2 more

Exclusion Criteria

I have fallen two or more times, or had a fall with injury, in the past year.
I do not have physical or mental issues that stop me from exercising safely.
Anticipated discharge or discharged before enrollment measures can be completed
See 17 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Intervention

Participants receive the ATTEND-CR intervention, which includes clinician notifications and a motivational interviewing phone call to encourage cardiac rehabilitation attendance

140 days
Remote follow-up calls and EHR review

Follow-up

Participants are monitored for safety and effectiveness after the intervention, including tracking of CR attendance, clinical events, and health outcomes

140 days
Remote follow-up calls and EHR review

What Are the Treatments Tested in This Trial?

Interventions

  • ATTEND-CR Intervention

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: Intervention Arm (ATTEND-CR):Experimental Treatment2 Interventions
Group II: Usual Care ArmActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Massachusetts General Hospital

Lead Sponsor

Trials
3,066
Recruited
13,430,000+

National Heart, Lung, and Blood Institute (NHLBI)

Collaborator

Trials
3,987
Recruited
47,860,000+

Citations

Effectiveness of quality improvement interventions in cardiac ...

Exercise-based cardiac rehabilitation for coronary heart disease. Cochrane ... Improved treatment of hospitalized coronary artery disease patients with ...

Cardiac Rehabilitation Attendance and Outcomes in ...

Cardiac rehabilitation (CR) is an efficacious yet underused treatment for patients with coronary artery disease. The objective of this study was to ...

Cardiac Rehabilitation (CRE)

... disease. Participation in CR can decrease recurrent cardiac-related events ... Compared with usual care, CR cost-effectiveness ratios range from $1,065 ...

Uptake and Effectiveness of Outpatient vs. Residential ... - PMC

Cardiac rehabilitation attendance and outcomes in coronary artery disease patients. ... Effectiveness of comprehensive cardiac rehabilitation ...

Use of Outpatient Cardiac Rehabilitation Among Heart ...

Each year, approximately 210,000 heart attacks are recurrent events. Outpatient cardiac rehabilitation among heart attack survivors helps to ...

Safety and long-term outcomes of remote cardiac ... - PMC

To systematically review the safety and the long-term mortality and morbidity risk-rates of the remotely-delivered cardiac rehabilitation (RDCR) interventions ...

Mortality Benefits of Cardiac Rehabilitation in Coronary ...

Cardiac rehabilitation (CR) is a multicomponent intervention to reduce adverse outcomes from coronary artery disease, but its mechanisms are ...

The role of cardiac rehabilitation in improving cardiovascular ...

This meta-analysis showed that participation in cardiac rehabilitation was associated with reduced rates of all-cause and heart-failure-specific hospitalization ...

Safety of home-based cardiac rehabilitation: A systematic ...

The risk of AEs during HBCR seems very low. Our results concerning the safety of HBCR should induce cardiac patients to be more active in their environment and ...

People who attend a full program of cardiac rehabilitation ...

People who attend a full program of cardiac rehabilitation (typically 36 sessions) have a 47 percent lower risk of death and a 31 percent lower ...