Feedback Program for Reducing Antibiotic Overprescription

ER
DS
Overseen ByDana Stanley, MET
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: University of British Columbia
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

The goal of this study is to evaluate an educational intervention that aims to reduce the number of unnecessary antibiotics prescribed by family physicians and nurse practitioners in British Columbia, Canada.

The intervention materials include a confidential personalized prescribing "portrait" and an evidence-based educational summary (therapeutics letter), accompanied by an introduction letter.

The main research questions are:

1. Will the intervention lead to a reduction in the overall number of antibiotics prescriptions started?

2. Will the intervention lead to a reduction in the proportion of antibiotics prescribed that are likely unnecessary, especially prescriptions for upper respiratory tract infections, acute bronchitis, acute sinusitis?

Researchers will conduct an intervention study with family physicians and nurse practitioners in British Columbia, Canada. Participant clinicians will be randomly assigned to one of two groups. The Early Group will consist of 80% of the participants and will receive the intervention (prescribing portrait, evidence summary, and introduction letter) at the start of the study. The Delayed Group will consist of 20% of participants and will receive the intervention about nine months later. This study design allows most practitioners to receive the intervention early while still allowing time to compare the two groups to assess the impact. To estimate the impact of the intervention, researchers will use administrative health data to compare the prescribing of the Early Group with prescribing of the Delayed Group.

Who Is on the Research Team?

CD

Colin Dormuth, ScD

Principal Investigator

University of British Columbia

Are You a Good Fit for This Trial?

Inclusion Criteria

Registered in 2024 with the BC Medical Services Plan (MSP) with a valid MSP billing number
Status of Salaried, Private Practice, Temporary Licence, or Post Graduate
Prescribed more than 100 dispensed medications in 2024

Exclusion Criteria

I have chosen not to participate in the Therapeutics Initiative Portrait program before.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Intervention

Early Group receives the prescribing portrait audit-and-feedback intervention at study initiation

9 months
Intervention materials mailed

Delayed Intervention

Delayed Group receives the prescribing portrait audit-and-feedback intervention approximately 9 months after the Early Group

9 months
Intervention materials mailed

Follow-up

Participants are monitored for changes in antibiotic prescribing rates and unnecessary prescriptions

39 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Prescribing portrait audit and feedback

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Group I: Early Group - Prescribing portrait audit and feedbackExperimental Treatment1 Intervention
Group II: Delayed control - Prescribing portrait audit-and-feedbackExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of British Columbia

Lead Sponsor

Trials
1,506
Recruited
2,528,000+

Ministry of Health, British Columbia

Collaborator

Trials
11
Recruited
15,600+

British Columbia Centre for Disease Control

Collaborator

Trials
11
Recruited
2,600+