Olive oil and Dietary Guideline recommendations for Trigeminal Neuralgia

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Food Science and Human Nutrition Department, University of Florida, Gainesville, FL
Trigeminal Neuralgia+2 More
Olive oil and Dietary Guideline recommendations - DietarySupplement
Eligibility
18+
Female
Eligible conditions
Select

Study Summary

This study is evaluating whether an olive oil dietary intervention might help reduce facial pain in people with trigeminal neuralgia.

See full description

Eligible Conditions

  • Trigeminal Neuralgia

Treatment Effectiveness

Effectiveness Progress

1 of 3

Other trials for Trigeminal Neuralgia

Study Objectives

This trial is evaluating whether Olive oil and Dietary Guideline recommendations will improve 1 primary outcome in patients with Trigeminal Neuralgia. Measurement will happen over the course of 12 weeks.

12 weeks
Compliance to olive oil intervention

Trial Safety

Safety Progress

1 of 3

Other trials for Trigeminal Neuralgia

Trial Design

2 Treatment Groups

Control
1 of 2
Olive Oil
1 of 2
Active Control
Experimental Treatment

This trial requires 70 total participants across 2 different treatment groups

This trial involves 2 different treatments. Olive Oil And Dietary Guideline Recommendations is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

Olive Oil
DietarySupplement
Incorporating 60 mL of olive oil into usual diet and Dietary Guidelines recommendations
Control
Other
Dietary Guidelines recommendations

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 12 weeks
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly 12 weeks for reporting.

Who is running the study

Principal Investigator
W. D.
Prof. Wendy Dahl, Associate Professor
University of Florida

Closest Location

Food Science and Human Nutrition Department, University of Florida - Gainesville, FL

Eligibility Criteria

This trial is for female patients aged 18 and older. There are 9 eligibility criteria to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
Diagnosed with Trigeminal Neuralgia
Able to provide written informed consent in English
Self-identifying females 18-99 years of age
Willing to consume 60 mL (4 tablespoons) of olive oil and accommodating dietary changes, and thereby achieve weight maintenance.
Willing to provide information about dietary intake at baseline, at the study midpoint, and at the end of the study to assess dietary changes.
Willing to complete online questionnaires associated with the study.
Willing and able to provide a valid social security for study payment purposes.
Have access to the internet to complete online questionnaires
Willing to maintain confidentiality of the Penn Facial Pain Scale

Patient Q&A Section

What is trigeminal neuralgia?

"TGN is a very painful chronic neuropathic condition affecting the trigeminal nerve; characterized by pain that can spread to the scalp, neck, face, and shoulder and is usually constant for more than one year. In the first 2-3 years, most TGN cases are mild and are not seen by the patient, usually by the physician only. The cause of TGN is unknown, but many people with the disease attribute their pain to triggers on regular days or nights that have not been clearly identified. Patients have a poorer quality of life than normal people." - Anonymous Online Contributor

Unverified Answer

What causes trigeminal neuralgia?

"Trigeminal neuralgia is most commonly initiated by compression of cranial nerves, particularly the trigeminal nerve but also the ophthalmic nerve. The exact location and mechanism of compression have been difficult to determine but have included the foramen magnum and superior petrosal sinus. The high resolution magnetic resonance imaging, combined with radiographic, computerized tomography, and the angiographic studies, are useful tools in confirming the diagnosis of trigeminal neuralgia, but there is not yet evidence to support surgical decompression of the superior petrosal sinus as a treatment for trigeminal neuralgia. The pain is rarely relieved just by inserting an electrode at the trigeminal nerve root." - Anonymous Online Contributor

Unverified Answer

Can trigeminal neuralgia be cured?

"Recent findings suggests that there is no cure for trigeminal neuralgia. Patients must be aware of this fact and must continue to treat their condition effectively to avoid the debilitating effects of constant pain." - Anonymous Online Contributor

Unverified Answer

What are the signs of trigeminal neuralgia?

"Each of the symptoms of trigeminal neuralgia (continuous or ‘stoat’ cheek pain, facial sensory loss, and post-facial or post-neck pains) are not always present. Therefore, not presenting with the symptoms of trigeminal neuralgia implies that the facial pain is in fact due to a non-neuralgic source (e.g., trauma or tumour). In most cases, the cause of the facial pain is either a tumour or an inflammatory lesion. The history and characteristics of the headache may be of importance in differentiating the neuralgia headaches from non-neuralgic headaches." - Anonymous Online Contributor

Unverified Answer

What are common treatments for trigeminal neuralgia?

"Current treatments for [trigeminal neuralgia](https://www.withpower.com/clinical-trials/trigeminal-neuralgia) include drug and neurorehabilitation in combination with transections, and some people have complete relief of their symptoms over the long-term. Other options can be surgery, radiosurgery, transnasal electrical stimulation, nerve block, and the Gamma Knife. There is no single definitive treatment, but a multi-disciplinary approach including medical, surgical, and neuropsychological counseling are generally needed to achieve total pain relief." - Anonymous Online Contributor

Unverified Answer

How many people get trigeminal neuralgia a year in the United States?

"The number of patients with trigeminal neuralgia in the United States who suffer from the condition for more than three months is 5.5 per thousand. In the United Kingdom, however, the lifetime prevalence of trigeminal neuralgia is 2.5 per thousand." - Anonymous Online Contributor

Unverified Answer

What does olive oil and dietary guideline recommendations usually treat?

"Recent findings show that it seems that olive oil has no role in the management of TGN patients with some exceptions: TGN patients who are treated with olive oil have no better results. In TGN patients, dietary guideline treatment is helpful in terms of a lower need for narcotics and a better quality of life." - Anonymous Online Contributor

Unverified Answer

Who should consider clinical trials for trigeminal neuralgia?

"If an individual or his/her family does not want to try medication, then they should ask for clinical trials at their clinician's clinic before turning to a surgical treatment. Otherwise, this approach should be considered when surgical treatment is not considered technically achievable." - Anonymous Online Contributor

Unverified Answer

What are the common side effects of olive oil and dietary guideline recommendations?

"Despite the recommendations of an olive oil intake of 2-3 oz/day, we found no correlation between dietary consumption of olive oil and common side effects. Future nutrition education sessions should include this specific advice and discuss the nutritional aspects of olive oil and its possible side-effects\n" - Anonymous Online Contributor

Unverified Answer

How serious can trigeminal neuralgia be?

"Many patients with trigeminal neuropathies have little facial pain without neurologic signs and signs. The clinician should be aware of these findings. Trigeminal neuropathies involving both large and small trigeminal nerves should be considered as candidates for surgical therapy. Trigeminal neuropathies can be potentially disabling and disabling or disabling in many respects." - Anonymous Online Contributor

Unverified Answer

Is olive oil and dietary guideline recommendations safe for people?

"Olive oil and DGI guidelines may not pose a risk for cardiovascular diseases in healthy population. Moreover, people on DGI have no more risk to CVD. It is important for consumers to know that there is no reason to eliminate DGI from eating a healthy and healthy diet." - Anonymous Online Contributor

Unverified Answer

Have there been any new discoveries for treating trigeminal neuralgia?

"While we continue the search relentlessly, some important breakthroughs have been recently made. We should keep up with their pace as they keep on emerging. The most recent and most important is the discovery of a new kind of medical treatment, known as microstimulation. It is a sort of mini-surgery which can cure trigeminal neuralgia for a few months. Microstimulation may also help patients with other types of chronic pain." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
See if you qualify for this trial
Get access to this novel treatment for Trigeminal Neuralgia by sharing your contact details with the study coordinator.