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Cardiac MRI for Heart Issues After Sepsis in Pediatric Cancer Patients

N/A

Recruiting

Led By Anthony Merlocco, MD

Research Sponsored by St. Jude Children's Research Hospital

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Between 9 and 25 years of age at time of study enrollment

Be younger than 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up within 10 days of presentation

Awards & highlights

Study Summary

This trial aims to identify heart issues in kids with cancer after sepsis, and use MRI tests to guide treatment decisions.

Who is the study for?

This trial is for pediatric cancer patients at St. Jude, aged 9-25, who have recently suffered from severe sepsis. They must be stable enough post-sepsis to undergo a cardiac MRI without anesthesia and not have significant heart dysfunction or conditions that make MRI unsafe.Check my eligibility

What is being tested?

The study tests the use of cardiac MRI to detect heart issues in children with cancer after sepsis. It checks if MRIs can be done safely soon after sepsis and how often these scans show heart inflammation or dysfunction within 10 days of a severe sepsis episode.See study design

What are the potential side effects?

Cardiac MRI is generally safe but may include discomfort due to lying still during the scan, loud noises from the machine, and potential reactions to contrast agents used for clearer images if applicable.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am between 9 and 25 years old.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ within 10 days after onset of sepsis

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~within 10 days after onset of sepsis

This trial's timeline: 3 weeks for screening, Varies for treatment, and within 10 days after onset of sepsis for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Feasibility of cardiac MRI in pediatric oncology patients with sepsis

Frequency of subacute sepsis-associated cardiac disease

Trial Design

1Treatment groups

Experimental Treatment

Group I: Cardiac MRI after sepsisExperimental Treatment1 Intervention

Participants who meet the eligibility criteria of severe sepsis.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Cardiac MRI

2017

Completed Phase 4

~3280

0 / 1Eligibility criteria met

Find a Location

Who is running the clinical trial?

St. Jude Children's Research HospitalLead Sponsor

428 Previous Clinical Trials

5,306,593 Total Patients Enrolled

Anthony Merlocco, MDPrincipal InvestigatorSt. Jude Children's Research Hospital

Media Library

Cardiac MRI after sepsis Clinical Trial Eligibility Overview. Trial Name: NCT05930418 — N/A

Acute Respiratory Distress Syndrome Research Study Groups: Cardiac MRI after sepsis

Cardiac MRI after sepsis 2023 Treatment Timeline for Medical Study. Trial Name: NCT05930418 — N/A

Acute Respiratory Distress Syndrome Clinical Trial 2023: Cardiac MRI after sepsis Highlights & Side Effects. Trial Name: NCT05930418 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Would I be eligible to join this medical research project?

"This clinical trial seeks to recruit 20 participants aged between 9 and 25 that have been diagnosed with acute respiratory distress syndrome."

Answered by AI

Is the age range for acceptance in this experiment limited to only those over 35?

"The protocols established for this clinical trial stipulate that those queuing to take part in the research must be between 9 and 25 years old. Furthermore, there are 94 trials specifically designed for minors and 326 intended for individuals over 65."

Answered by AI

How many individuals are contributing to the data of this investigation?

"Yes, according to clinicaltrials.gov the trial is still recruiting subjects. This study was made available on April 14th 2023 and has been revised as recently as June 24th 2023. At present, there is an opening for up to twenty patients at a single medical facility."

Answered by AI

Are there any open slots for participants in this investigation?

"Affirmative. Records on clinicaltrials.gov attest to this medical trial's current recruitment efforts, which were kickstarted on April 14th of 2023 and more recently updated on June 24th 2023. In total, the study is hoping to source 20 individuals from a single site."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Cardiovascular Magnetic Resonance Prognosticators in Pediatric Oncology Patients With Sepsis

2023. "Cardiovascular Magnetic Resonance Prognosticators in Pediatric Oncology Patients With Sepsis". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05930418.

All > Sepsis > Ards