XS Muscle Multiplier for Sarcopenia

DD
Overseen ByDavid D Church, Ph.D.
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to explore how muscles process amino acids, the building blocks of protein, to assess muscle health. It involves an oral amino acid test similar to a glucose test for diabetes, using a supplement called XS Muscle Multiplier. This method could provide an easy way for doctors to check muscle health before any loss of function occurs. Suitable participants include those who have been using protein supplements and are willing to stop for a week before the test, and who do not have certain medical conditions like diabetes requiring insulin. As an unphased trial, this study offers participants the chance to contribute to groundbreaking research that could enhance muscle health assessments.

Will I have to stop taking my current medications?

The trial does not specify if you need to stop taking your current medications, but you cannot use protein or amino acid supplements for 7 days before Visit 2, and you cannot use corticosteroids, testosterone, or similar anabolic agents.

What prior data suggests that this oral amino acid tolerance test is safe?

Research has shown that the XS Muscle Multiplier is generally safe for users. NSF International, a global organization focused on public health and safety, has certified the supplement. This certification confirms that the product meets safety standards.

The XS Muscle Multiplier contains important nutrients such as essential amino acids (EAAs), branched-chain amino acids (BCAAs), L-Glutamine, and L-Arginine, which aid in muscle growth and recovery. No major side effects have been reported from these ingredients.

The product undergoes testing to ensure it does not contain banned substances, making it safe for athletes and others who must adhere to substance regulations. Overall, based on available data, the XS Muscle Multiplier is considered safe.12345

Why are researchers excited about this trial?

XS Muscle Multiplier is unique because it focuses on enhancing muscle mass through a nutritional approach, which is different from the standard treatments for sarcopenia like resistance exercise and protein supplementation. This treatment stands out due to its use of a commercially available nutritional supplement that can be ingested in a single 10g dose, making it potentially more convenient and accessible. Researchers are excited about XS Muscle Multiplier because it might offer a simpler, more direct way to support muscle health, potentially addressing sarcopenia more efficiently than existing methods.

What evidence suggests that the XS Muscle Multiplier might be an effective treatment for assessing muscle health?

Research shows that essential amino acids (EAAs), such as those in XS Muscle Multiplier, are crucial for building and repairing muscles. Studies have found that EAA supplements aid muscle recovery and growth after exercise by boosting muscle protein production. Additionally, adequate EAA intake may enhance muscle health and recovery in athletes. This trial will evaluate the effects of XS Muscle Multiplier, with participants ingesting 10g of the nutritional product. Although more research is needed, these findings provide a hopeful outlook for those seeking to support muscle health with EAA supplements.678910

Who Is on the Research Team?

DD

David D Church, Ph.D.

Principal Investigator

University of Arkansas

Are You a Good Fit for This Trial?

Inclusion Criteria

Ages 18 - 30 and 70-89 yrs
For the sarcopenic group, a SARC-F score of ≥ 4 at the screening visit

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants ingest 10g of a commercially available nutritional supplement during a study visit to assess skeletal muscle amino acid kinetics

1 day
1 visit (in-person)

Follow-up

Participants are monitored for plasma leucine concentration over a 5-hour period after ingestion

5 hours

What Are the Treatments Tested in This Trial?

Interventions

  • XS Muscle Multiplier
How Is the Trial Designed?
1Treatment groups
Experimental Treatment
Group I: 10g of nutritional productExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Arkansas

Lead Sponsor

Trials
500
Recruited
153,000+

Citations

XS™ Muscle Multiplier Scientific Rationale by Marissa ...An oral essential amino acid-carbohydrate supplement enhances muscle protein anabolism after resistance exercise. J Appl Physiol. 2000; 88: 386- ...
XS™ Muscle Multiplier™EAAs are essential to stimulating and producing vital proteins in the body, and protein is important to help your body repair cells and make new ones1.
Nutritional Biomarkers of Sarcopenia - ClinicalTrials.VeevaThis study proposes to characterize skeletal muscle amino acid ... Dietary Supplement: XS Muscle Multiplier. Study type. Interventional.
XS Muscle MultiplierClinical studies demonstrate that adequate EAA intake can significantly enhance muscle recovery and overall health outcomes in athletes and ...
A Dietary Supplement Containing Essential Amino Acids in ...Conclusions: These results demonstrate the potential value of EAA supplementation as part of a comprehensive approach to support physical.
XS™ Muscle Multiplier - Berry Blast | NutritionXS™ Muscle Multiplier*† supplement is also Contents Certified by NSF International, a global organization dedicated to public health and safety. This ...
Banned Substance Tested Supplement ListInformed Sport has more than 1200 banned substance tested and certified sports nutrition products from brands around the world. View the full list here!
XS™ Muscle Multiplier*† – Watermelon | NutritionXS™ Muscle Multiplier*† supplement is also Contents Certified by NSF International, a global organization dedicated to public health and safety. This ...
XS Muscle Multiplier_e-leaflet_ENG.pdfXS Muscle Multiplier contains EAA, BCAA, L-Glutamine & L-Arginine, boosts muscle mass growth, supports muscle protein synthesis, and fuels muscle recovery.
Are the ingredients in XS Energy drinks any good/unhealthy?The only ingredient that is of significant levels is Vitamin B12. A safe upper limit for B12 has not been established as no adverse effects have ...
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