30 Participants Needed

Nutritional Biomarkers of Sarcopenia

DD
Overseen ByDavid D Church, Ph.D.
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial uses a drink with essential amino acids to check muscle health in older adults at risk of muscle loss. By seeing how muscles react to these amino acids, doctors can spot problems early, potentially preventing further muscle loss and weakness. Essential amino acids have been shown to effectively stimulate muscle growth and improve muscle mass, strength, and function in elderly individuals.

Will I have to stop taking my current medications?

The trial does not specify if you need to stop taking your current medications, but you cannot use protein or amino acid supplements for 7 days before Visit 2, and you cannot use corticosteroids, testosterone, or similar anabolic agents.

Who Is on the Research Team?

DD

David D Church, Ph.D.

Principal Investigator

University of Arkansas

Are You a Good Fit for This Trial?

Inclusion Criteria

Ages 18 - 30 and 70-89 yrs
For the sarcopenic group, a SARC-F score of ≥ 4 at the screening visit

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants ingest 10g of a commercially available nutritional supplement during a study visit to assess skeletal muscle amino acid kinetics

1 day
1 visit (in-person)

Follow-up

Participants are monitored for plasma leucine concentration over a 5-hour period after ingestion

5 hours

What Are the Treatments Tested in This Trial?

Interventions

  • XS Muscle Multiplier
How Is the Trial Designed?
1Treatment groups
Experimental Treatment
Group I: 10g of nutritional productExperimental Treatment1 Intervention
All subjects will ingest 10g of a commercially available nutritional supplement one time during a study visit.

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Arkansas

Lead Sponsor

Trials
500
Recruited
153,000+
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