Preoperative Diet for Surgical Outcomes
Trial Summary
What is the purpose of this trial?
The aim of the study is to evaluate the gut microbiome (i.e. bacteria, viruses, and fungi that reside in the gut) of people undergoing abdominal surgery, evaluate whether specific diets can change the gut microbiome, and, if so, whether those changes translate into better surgical outcomes.
Eligibility Criteria
This trial is for English or Spanish-speaking individuals scheduled for major abdominal colorectal surgery with intestinal resection in at least two weeks. It excludes those who are hearing impaired, without smartphone access, homeless, decisionally impaired, lacking an ileostomy prior to surgery, or having a procedure without intestinal resection.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Enrollment
Participants are enrolled and randomized to dietary interventions
Intervention
Participants follow assigned diet (low-fat/high-fiber, high-fermented, or control) for 10-14 days before surgery
Surgery
Participants undergo abdominal surgery and samples are collected
Follow-up
Participants are monitored for surgical outcomes and microbiome changes for 30 days post-surgery
Treatment Details
Interventions
- Fermented Diet
- High-Fiber/Low Fat Diet
Find a Clinic Near You
Who Is Running the Clinical Trial?
Stanford University
Lead Sponsor