Music for Opioid Use Disorder
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to explore how music might influence cravings and recovery for people with opioid use disorder. Participants will listen to music or silence and then evaluate their cravings for opioids after viewing images related to drug use. The goal is to determine if music can lessen cravings and aid in recovery. Individuals currently receiving stable treatment for opioid use disorder with buprenorphine or methadone might be a good fit.
As an unphased trial, this study offers a unique opportunity to contribute to innovative research that could enhance recovery strategies for opioid use disorder.
Will I have to stop taking my current medications?
The trial requires participants to be on a stable dose of buprenorphine or methadone for at least 30 days, so you will not need to stop these medications. However, you cannot participate if you are currently prescribed naltrexone or require prescription opioid painkillers during the trial.
What prior data suggests that this music intervention is safe for individuals with opioid use disorder?
Research has shown that music is safe for people. In some studies, patients who listened to music felt better and experienced less stress. Evidence also suggests that music might help reduce the use of drugs, including opioids. Other research has demonstrated that music can lower pain and the need for pain medication after surgery. Overall, listening to music appears well-tolerated, with no major side effects reported. This suggests it could be a safe option for those seeking help with opioid cravings.12345
Why are researchers excited about this trial?
Researchers are excited about using music as a treatment for opioid use disorder because it offers a non-pharmacological approach that could complement existing therapies like medication-assisted treatment (MAT) and behavioral therapy. Unlike traditional medications that target the brain's chemistry, music intervention may help manage cravings through emotional and psychological engagement, providing a soothing, personalized experience. This method could be particularly appealing as it avoids the side effects associated with drugs and could be easily integrated into various treatment settings, offering a holistic approach to recovery.
What evidence suggests that this music intervention might be an effective treatment for opioid use disorder?
Research has shown that music therapy can help reduce cravings for drugs, including opioids. In this trial, one group of participants will receive a music intervention, listening to songs of their choice to assess its impact on opioid cravings. Studies have found that combining music with regular treatment often reduces the desire to use drugs. Music therapy appears to help by affecting brain processes related to cravings. Listening to music might also boost mood and serve as a positive distraction from addiction triggers. This suggests that music could be useful in managing opioid use disorder.678910
Who Is on the Research Team?
Scott G Weiner, MD, MPH
Principal Investigator
Brigham and Women's Hospital
Are You a Good Fit for This Trial?
This trial is for individuals who are dealing with opioid addiction or dependence. The study aims to understand if music can influence their cravings and recovery process.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants undergo a single session at the Center for Clinical Investigation, where they complete questionnaires, listen to music or silence, and are exposed to drug-related and neutral cues.
Qualitative Interview
Participants engage in a qualitative interview discussing their relationship with music and its impact on their opioid use and recovery.
Follow-up
Participants are monitored for any feedback on the trial and potential strategies for music use in clinical settings.
What Are the Treatments Tested in This Trial?
Interventions
- Music Intervention
Trial Overview
The trial is exploring the effect of music on opioid cravings by comparing reactions to silence versus a music intervention in participants with opioid use disorder.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Placebo Group
In this arm, subjects will rate their cravings for opioids on a 0-100 point visual analog scale. They will then listen to 2 songs of their choosing. They will then be shown a series of images "cues" related to drug use, and will again be asked their cravings for opioids.
In this arm, subjects will rate their cravings for opioids on a 0-100 point visual analog scale. They will then listen to 10 minutes of silence. They will then be shown a series of images "cues" related to drug use, and will again be asked their cravings for opioids.
Find a Clinic Near You
Who Is Running the Clinical Trial?
Brigham and Women's Hospital
Lead Sponsor
Published Research Related to This Trial
Citations
Music therapy for people with substance use disorders - PMC
Results from this review suggest that MT as 'add on' treatment to standard care can lead to moderate reductions in substance craving and can increase ...
A qualitative inquiry into music consumption at drug ...
This qualitative study offers a retrospective perspective on clients with SUD at treatment centers, exploring the impact of music consumption and music therapy ...
Music therapy for people with substance use disorders
Our findings suggest that music therapy added to standard care likely reduces substance craving when compared to standard care alone for people ...
Music therapy, neural processing, and craving reduction
Music therapy has been shown to be effective for multiple clinical endpoints associated with substance use disorder such as craving reduction, ...
Music as an Adjunct to Opioid-Based Analgesia - PMC
These concepts may alter the efficacy of music in substance abuse treatment if deployed as a part of group therapy in comparison to individual therapy sessions.
Effect and safety of listening to music or audiobooks as a ...
This study's primary objective is to provide the first evidence on the distinct (separate) effects of music listening as a coadjuvant ...
Is Music Therapy Efficacious in Treating Patients with ...
Findings show that few descriptions of music therapies, and even fewer studies reporting outcomes of music therapies exist for the treatment of patients with ...
Virtual Music Therapy for Substance Use Disorders in a ...
Patients reported an improvement in mood and their ability to manage stress, and a decrease in substance use. Conclusion: We wish to build on ...
The psychophysiology of music-based interventions and ...
Some trials report decreased opioid use after music-based therapy ... Endogenous opioid systems alterations in pain and opioid use disorder. Front ...
Implementation of Music Intervention for Acute ...
The result demonstrated that music is statistically and clinically significant in reducing the postoperative pain score and opioids administered ...
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