Trust-based Relational Intervention Training for Opioid Use Disorder
Phase-Based Progress Estimates
Effectiveness
Safety
Grayson County Juvenile Center/Boot Camp, Denison, TXOpioid Use Disorder+1 MoreTrust-based Relational Intervention Training - Behavioral
Study Summary
This trial will test an intervention to prevent opioid misuse among older adolescents involved in the juvenile justice system.
Eligible Conditions
- Opioid Use Disorder
- Substance Abuse
Treatment Effectiveness
Effectiveness Progress
Study Objectives
3 Primary · 15 Secondary · Reporting Duration: 15 months
15 months
Anxiety (both youth and caregivers)
Behavioral problems (youth)
Depression (both youth and caregivers)
Family relationship
Frequency of opioid overdose
Frequency of receiving substance use treatment
Monthly check-ins on anxiety, depression, and stress in the relationship with caregiver/safe adult (youth)
Monthly check-ins on behavioral misconduct (youth)
Pain (both youth and caregivers)
Prosocial behavior (youth)
Receipt of Narcan for opioid overdose
Recidivism
Self-efficacy (youth)
Self-regulation (youth) - delayed discounting
Self-regulation (youth) - emotion regulation
Self-regulation (youth) - executive functioning
Self-regulation (youth) - positive and negative urgency
Social exposure to alcohol, marijuana, heroin, and prescription opioids (youth)
Times of hospital visits related to substance use
Times of treatment referral for substance use
Youth and caregiver relationship
Youth days to opioid (and other substance use) initiation
Youth months to opioid (and other substance use) initiation
Alcohol or Other Drugs use
Trial Safety
Safety Progress
Trial Design
7 Treatment Groups
Standard Reentry Practice
1 of 7
TBRI Group Training + TBRI In-Home Responsive Coaching
1 of 7
TBRI Group Training only
1 of 7
TBRI Group Training + TBRI In-Home Structured Coaching
1 of 7
TBRI Training only
1 of 7
TBRI Training + TBRI In-Home Structured Coaching
1 of 7
TBRI Training + TBRI In-Home Responsive Coaching
1 of 7
Active Control
Experimental Treatment
360 Total Participants · 7 Treatment Groups
Primary Treatment: Trust-based Relational Intervention Training · No Placebo Group · N/A
TBRI Group Training + TBRI In-Home Responsive CoachingExperimental Group · 2 Interventions: Trust-based Relational Intervention Group Training, Trust-based Relational Intervention In-Home Responsive Coaching · Intervention Types: Behavioral, Behavioral
TBRI Group Training only
Behavioral
Experimental Group · 1 Intervention: Trust-based Relational Intervention Group Training · Intervention Types: BehavioralTBRI Group Training + TBRI In-Home Structured CoachingExperimental Group · 2 Interventions: Trust-based Relational Intervention Group Training, Trust-based Relational Intervention In-Home Structured Coaching · Intervention Types: Behavioral, Behavioral
TBRI Training only
Behavioral
Experimental Group · 1 Intervention: Trust-based Relational Intervention Training · Intervention Types: BehavioralTBRI Training + TBRI In-Home Structured CoachingExperimental Group · 2 Interventions: Trust-based Relational Intervention Training, Trust-based Relational Intervention In-Home Structured Coaching · Intervention Types: Behavioral, Behavioral
TBRI Training + TBRI In-Home Responsive CoachingExperimental Group · 2 Interventions: Trust-based Relational Intervention Training, Trust-based Relational Intervention In-Home Responsive Coaching · Intervention Types: Behavioral, Behavioral
Standard Reentry PracticeNoIntervention Group · 1 Intervention: Standard Reentry Practice · Intervention Types:
Trial Logistics
Trial Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 15 months
Who is running the clinical trial?
Texas Christian UniversityLead Sponsor
24 Previous Clinical Trials
3,094 Total Patients Enrolled
Danica K Knight, Ph.D.Principal InvestigatorTexas Christian University
1 Previous Clinical Trials
839 Total Patients Enrolled
Eligibility Criteria
Age 15 - 20 · All Participants · 5 Total Inclusion Criteria
Mark “Yes” if the following statements are true for you:You are not currently at risk of harming yourself.
References
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Frequently Asked Questions
Is it feasible for individuals aged 80 and above to participate in this trial?
"Accordingly, the requirements for inclusion in this medical study stipulate that applicants must be between 15 and 20 years old." - Anonymous Online Contributor
Unverified Answer
Is this research actively recruiting participants?
"According to the official clinicaltrials.gov page, this medical experiment is still recruiting participants. It was first advertised on February 15th 2021 and recent amendments were made as recently as August 26th 2022." - Anonymous Online Contributor
Unverified Answer
What criteria must be met for individuals to qualify to join this clinical trial?
"This medical experiment is currently looking for 360 participants aged 15 to 20 with a history of opioid abuse. Other prerequisites include being supervised or cared by the staff involved in this trial, not showing any signs of suicide risk and having access to one safe adult who will be part of the study as well." - Anonymous Online Contributor
Unverified Answer
What are the main aims of this clinical trial?
"This 15-month trial will evaluate the effectiveness of reducing opioid (and other substances) initiation amongst youth. Secondary outcomes include assessing self-regulation and executive functioning using Barkley Deficits in Executive Functioning Scale-Child and Adolescent Short Form, tracking behavioural misconduct, as well as social exposure to alcohol, marijuana, heroin, prescription opioids via Four items developed by HEAL Prevention Cooperative. Scores for all metrics range from 1 - 4 or 0 - 3 with higher scores indicating a worse outcome.." - Anonymous Online Contributor
Unverified Answer
What is the current rate of participation in this research endeavor?
"Affirmative. Data hosted on clinicaltrials.gov suggests that this medical study is still recruiting, having initially been posted on February 15th 2021 and last edited on August 26th 2022. 360 volunteers are needed for the 9 different sites running the trial." - Anonymous Online Contributor
Unverified Answer
How many separate sites are engaged in conducting this trial?
"This research is taking place at 9 different sites. Naperville, Harrisburg and Grafton are just three of the locations participants can choose from to reduce travel time." - Anonymous Online Contributor
Unverified Answer