Trust-based Relational Intervention Training for Opioid Use Disorder
This trial will test an intervention to prevent opioid misuse among older adolescents involved in the juvenile justice system.
- Opioid Use Disorder
- Substance Abuse
3 Primary · 15 Secondary · Reporting Duration: 15 months
7 Treatment Groups
Standard Reentry Practice
1 of 7
TBRI Group Training + TBRI In-Home Responsive Coaching
1 of 7
TBRI Group Training only
1 of 7
TBRI Group Training + TBRI In-Home Structured Coaching
1 of 7
TBRI Training only
1 of 7
TBRI Training + TBRI In-Home Structured Coaching
1 of 7
TBRI Training + TBRI In-Home Responsive Coaching
1 of 7
360 Total Participants · 7 Treatment Groups
Primary Treatment: Trust-based Relational Intervention Training · No Placebo Group · N/A
Who is running the clinical trial?
Age 15 - 20 · All Participants · 5 Total Inclusion CriteriaMark “Yes” if the following statements are true for you:
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- Stein, Michael D., Micah T. Conti, Shannon Kenney, Bradley J. Anderson, Jessica N. Flori, Megan M. Risi, and Genie L. Bailey. 2017. “Adverse Childhood Experience Effects on Opioid Use Initiation, Injection Drug Use, and Overdose Among Persons with Opioid Use Disorder”. Drug and Alcohol Dependence. Elsevier BV. doi:10.1016/j.drugalcdep.2017.07.007.
- Taxman, Faye S., Douglas W. Young, and Bennett W. Fletcher. 2007. “The National Criminal Justice Treatment Practices Survey: An Overview of the Special Issue”. Journal of Substance Abuse Treatment. Elsevier BV. doi:10.1016/j.jsat.2006.12.017.
- Tolou-Shams, Marina, Wendy Hadley, Selby M. Conrad, and Larry K. Brown. 2011. “The Role of Family Affect in Juvenile Drug Court Offenders’ Substance Use and HIV Risk”. Journal of Child and Family Studies. Springer Science and Business Media LLC. doi:10.1007/s10826-011-9498-4.
- Brown, Larry K., Nicholas Tarantino, Marina Tolou-Shams, Christianne Esposito-Smythers, Meredith G. Healy, and Lacey Craker. 2017. “Mental Health Symptoms and Parenting Stress of Parents of Court-involved Youth”. Journal of Child and Family Studies. Springer Science and Business Media LLC. doi:10.1007/s10826-017-0923-1.
- Laird, Robert D., Gregory S. Pettit, John E. Bates, and Kenneth A. Dodge. 2003. “Parents' Monitoring-relevant Knowledge and Adolescents' Delinquent Behavior: Evidence of Correlated Developmental Changes and Reciprocal Influences”. Child Development. Wiley. doi:10.1111/1467-8624.00566.
- Quinn, Kelly, Bartley C. Frueh, Joy Scheidell, Daniel Schatz, Faith Scanlon, and Maria R. Khan. 2019. “Internalizing and Externalizing Factors on the Pathway from Adverse Experiences in Childhood to Non-medical Prescription Opioid Use in Adulthood”. Drug and Alcohol Dependence. Elsevier BV. doi:10.1016/j.drugalcdep.2018.12.029.
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- Shin, Sunny H., Shelby Elaine McDonald, and David Conley. 2018. “Patterns of Adverse Childhood Experiences and Substance Use Among Young Adults: A Latent Class Analysis”. Addictive Behaviors. Elsevier BV. doi:10.1016/j.addbeh.2017.11.020.
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- Dube, Shanta R., Jacqueline W. Miller, David W. Brown, Wayne H. Giles, Vincent J. Felitti, Maxia Dong, and Robert F. Anda. 2006. “Adverse Childhood Experiences and the Association with Ever Using Alcohol and Initiating Alcohol Use During Adolescence”. Journal of Adolescent Health. Elsevier BV. doi:10.1016/j.jadohealth.2005.06.006.
- Fosco, Gregory M., Jennifer L. Frank, Elizabeth A. Stormshak, and Thomas J. Dishion. 2013. “Opening the “black Box”: Family Check-up Intervention Effects on Self-regulation That Prevents Growth in Problem Behavior and Substance Use”. Journal of School Psychology. Elsevier BV. doi:10.1016/j.jsp.2013.02.001.
- Nelis, Delphine, Ilios Kotsou, Jordi Quoidbach, Michel Hansenne, Fanny Weytens, Pauline Dupuis, and Moïra Mikolajczak. 2011. “Increasing Emotional Competence Improves Psychological and Physical Well-being, Social Relationships, and Employability.”. Emotion. American Psychological Association (APA). doi:10.1037/a0021554.
- STEINBERG, LAURENCE. 2004. “Risk Taking in Adolescence: What Changes, and Why?”. Annals of the New York Academy of Sciences. Wiley. doi:10.1196/annals.1308.005.
- Tolou‐Shams, Marina, Leah Brogan, Christianne Esposito‐Smythers, Meredith G. Healy, Ashley Lowery, Lacey Craker, and Larry K. Brown. 2018. “The Role of Family Functioning in Parenting Practices of Court‐involved Youth”. Journal of Adolescence. Wiley. doi:10.1016/j.adolescence.2017.12.016.
- Forster, Myriam, Timothy J. Grigsby, Christopher J. Rogers, and Stephanie M. Benjamin. 2018. “The Relationship Between Family-based Adverse Childhood Experiences and Substance Use Behaviors Among a Diverse Sample of College Students”. Addictive Behaviors. Elsevier BV. doi:10.1016/j.addbeh.2017.08.037.
- Kumpfer, Karol L., Rose Alvarado, and Henry O. Whiteside. 2003. “Family-based Interventions for Substance Use and Misuse Prevention”. Substance Use & Misuse. Informa UK Limited. doi:10.1081/ja-120024240.
- Wolff, Kevin T., Michael T. Baglivio, and Alex R. Piquero. 2015. “The Relationship Between Adverse Childhood Experiences and Recidivism in a Sample of Juvenile Offenders in Community-based Treatment”. International Journal of Offender Therapy and Comparative Criminology. SAGE Publications. doi:10.1177/0306624x15613992.
- Council of State Governments Justice Center. (2017, September). Dos and don'ts for reducing recidivism among young adults in the justice system. Retrieved February 15, 2019 from https://csgjusticecenter.org/wp-content/uploads/2017/09/Dos-and-Donts-for-Reducing- Recidivism-among-Young-Adults-in-the-Justice-System.pdf
- Marrow, M. T., Knudsen, K. J., Olafson, E., & Bucher, S. E. (2012). The value of implementing TARGET within a trauma-informed Juvenile Justice Setting. Journal of Child & Adolescent Trauma, 5(3), 257-270. DOI: 10.1080/19361521.2012.697105
- O'Connell, M. E., O'Connell, T. Boat, & K. E. Warner (Eds.). (2009). Preventing mental, emotional, and behavioral disorders among young people: Progress and possibilities. Washington, DC: The National Academies Press.
- Wills, T. A., Sandy, J. M., Shinar, O., & Yaeger, A. (1999). Contributions of positive and negative affect to adolescent substance use: Test of a bidimensional model in a longitudinal study. Psychology of Addictive Behaviors, 13(4), 327-338. http://dx.doi.org/10.1037/0893-164X.13.4.327
- Wright, K. N., & Wright, K. E. (1993). Family life and delinquency and crime: A policymakers' guide to the literature (NCJ 140517). Washington, DC: U.S. Department of Justice, Office of Juvenile Justice and Delinquency Prevention, National Institute of Justice. Retrieved March 8, 2019 from https://www.ncjrs.gov/pdffiles1/Digitization/140517NCJRS.pdf
- Murray, D. W., Rosanbalm, K., & Christopoulos, C. (2016, February). Self-Regulation and toxic stress report 3: A comprehensive review of self-regulation interventions from birth through young adulthood (OPRE Report # 2016-34). Washington, DC: Office of Planning, Research and Evaluation, Administration for Children and Families, U.S. Department of Health and Human Services. Retrieved February 14, 2019 from https://www.acf.hhs.gov/sites/default/files/opre/acf_report_3_approved_fromword_b508. pdf
- Texas Senate Bill 1356. (2013, September 1). About Texas Senate Bill 1356. Retrieved March 8, 2019 from https://www.crisisprevention.com/Blog/August-2013/Texas-Senate-Bill-1356?lang=en-US
- Zolkoski, S. M., & Bullock, L. M. (2012). Resilience in children and youth: A review. Children and Youth Services Review, 34(12), 2295-2303. http://dx.doi.org/10.1016/j.childyouth.2012.08.009
- Baglivio, M. T., & Epps, N. (2016). The interrelatedness of adverse childhood experiences among high-risk juvenile offenders. Youth Violence and Juvenile Justice, 14(3), 179-198.
- National Center for Mental Health and Juvenile Justice. (2016, September). Trauma among youth in the Juvenile Justice System. Retrieved March 7, 2019 from https://www.ncmhjj.com/wp-content/uploads/2016/09/Trauma-Among-Youth-in-the- Juvenile-Justice-System-for-WEBSITE.pdf
- Baglivio, M. T., Wolff, K. T., Piquero, A. R., & Epps, N. (2015). The relationship between Adverse Childhood Experiences (ACE) and juvenile offending trajectories in a juvenile offender sample. Journal of Criminal Justice, 43(3), 229-241.
- Hovdestad, W. E., Tonmyr, L., Wekerle, C., & Thornton, T. (2011). Why is childhood maltreatment associated with adolescent substance abuse? A critical review of explanatory models. International Journal of Mental Health Addiction, 9(5), 525-542. DOI: 10.1007/s11469-011-9322-9
- Frisman, L., Ford, J., Lin, H.-J., Mallon, S., & Chang, R. (2008). Outcomes of trauma treatment using the TARGET Model. https://doi.org/10.1080/15560350802424910
- Evans-Chase, M. (2014). Addressing trauma and psychosocial development in juvenile justice- involved youth: A synthesis of the developmental neuroscience, juvenile justice and trauma literature. Laws, 3(4), 744-758. DOI: 10.3390/laws3040744
- Ford, J. D., & Hawke, J. (2012). Trauma affect regulation psychoeducation group and milieu intervention outcomes in juvenile detention facilities. Journal of Aggression, Maltreatment & Trauma, 21(4), 365-384. https://doi.org/10.1080/10926771.2012.673538
- Knight, Danica Kalling, Yang Yang, Elizabeth D. Joseph, Elaine Tinius, Shatoya Young, Lillyan T. Shelley, David R. Cross, and Kevin Knight. 2021. “Preventing Opioid Use Among Justice-involved Youth as They Transition to Adulthood: Leveraging Safe Adults (lesa)”. BMC Public Health. Springer Science and Business Media LLC. doi:10.1186/s12889-021-12127-3.
- Preventing Mental, Emotional, and Behavioral Disorders Among Young People. 2009. Preventing Mental, Emotional, and Behavioral Disorders Among Young People. . National Academies Press. doi:10.17226/12480.
- National Research Council (US) and Institute of Medicine (US) Committee on the Prevention of Mental Disorders and Substance Abuse Among Children, Youth, and Young Adults: Research Advances and Promising Interventions; O'Connell ME, Boat T, Warner KE, editors. Preventing Mental, Emotional, and Behavioral Disorders Among Young People: Progress and Possibilities. Washington (DC): National Academies Press (US); 2009. Available from http://www.ncbi.nlm.nih.gov/books/NBK32775/
- Steinberg L. Risk taking in adolescence: what changes, and why? Ann N Y Acad Sci. 2004 Jun;1021:51-8. doi: 10.1196/annals.1308.005.
- Kumpfer KL, Alvarado R, Whiteside HO. Family-based interventions for substance use and misuse prevention. Subst Use Misuse. 2003 Sep-Nov;38(11-13):1759-87. doi: 10.1081/ja-120024240.
- Biederman J, Faraone SV, Monuteaux MC, Feighner JA. Patterns of alcohol and drug use in adolescents can be predicted by parental substance use disorders. Pediatrics. 2000 Oct;106(4):792-7. doi: 10.1542/peds.106.4.792.
- Tolou-Shams M, Hadley W, Conrad SM, Brown LK. The Role of Family Affect in Juvenile Drug Court Offenders' Substance Use and HIV Risk. J Child Fam Stud. 2012 Jun 1;21(3):449-456. doi: 10.1007/s10826-011-9498-4. Epub 2011 May 6.
- Laird RD, Pettit GS, Bates JE, Dodge KA. Parents' monitoring-relevant knowledge and adolescents' delinquent behavior: evidence of correlated developmental changes and reciprocal influences. Child Dev. 2003 May-Jun;74(3):752-68. doi: 10.1111/1467-8624.00566.
- Taxman FS, Young DW, Fletcher BW. The National Criminal Justice Treatment Practices survey: an overview of the special issue. J Subst Abuse Treat. 2007 Apr;32(3):221-3. doi: 10.1016/j.jsat.2006.12.017. Epub 2007 Mar 9. No abstract available.
- Dube SR, Miller JW, Brown DW, Giles WH, Felitti VJ, Dong M, Anda RF. Adverse childhood experiences and the association with ever using alcohol and initiating alcohol use during adolescence. J Adolesc Health. 2006 Apr;38(4):444.e1-10. doi: 10.1016/j.jadohealth.2005.06.006.
- 2021. "Preventing Opioid Use Among Justice-involved Youth as They Transition to Adulthood Leveraging Safe Adults (LeSA)". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04678960.
Frequently Asked Questions
Is it feasible for individuals aged 80 and above to participate in this trial?
"Accordingly, the requirements for inclusion in this medical study stipulate that applicants must be between 15 and 20 years old." - Anonymous Online Contributor
Is this research actively recruiting participants?
"According to the official clinicaltrials.gov page, this medical experiment is still recruiting participants. It was first advertised on February 15th 2021 and recent amendments were made as recently as August 26th 2022." - Anonymous Online Contributor
What criteria must be met for individuals to qualify to join this clinical trial?
"This medical experiment is currently looking for 360 participants aged 15 to 20 with a history of opioid abuse. Other prerequisites include being supervised or cared by the staff involved in this trial, not showing any signs of suicide risk and having access to one safe adult who will be part of the study as well." - Anonymous Online Contributor
What are the main aims of this clinical trial?
"This 15-month trial will evaluate the effectiveness of reducing opioid (and other substances) initiation amongst youth. Secondary outcomes include assessing self-regulation and executive functioning using Barkley Deficits in Executive Functioning Scale-Child and Adolescent Short Form, tracking behavioural misconduct, as well as social exposure to alcohol, marijuana, heroin, prescription opioids via Four items developed by HEAL Prevention Cooperative. Scores for all metrics range from 1 - 4 or 0 - 3 with higher scores indicating a worse outcome.." - Anonymous Online Contributor
What is the current rate of participation in this research endeavor?
"Affirmative. Data hosted on clinicaltrials.gov suggests that this medical study is still recruiting, having initially been posted on February 15th 2021 and last edited on August 26th 2022. 360 volunteers are needed for the 9 different sites running the trial." - Anonymous Online Contributor
How many separate sites are engaged in conducting this trial?
"This research is taking place at 9 different sites. Naperville, Harrisburg and Grafton are just three of the locations participants can choose from to reduce travel time." - Anonymous Online Contributor